CADENCE-KIDS: Cadence and Intensity in Children and Adolescents

CADENCE-KIDS：儿童和青少年的节奏和强度

• 批准号: 8582718
• 负责人: CATRINE E. TUDOR-LOCKE
• 金额: $ 18.5万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8582718
• 关键词: 10 year old; 15 year old; 20 year old; Adolescent; Adolescent Behavior; Adult; Age; Age-Years; Biological Neural Networks; Biomedical Research; Child; Classification; Clinical; Communities; Complex; Data; Development; Devices; Digit structure; Equation; Exercise stress test; Exploratory/Developmental Grant; Frequencies; Frustration; Future; Gait; Generic Drugs; Guidelines; Health Benefit; Indirect Calorimetry; Individual; Investigation; Laboratories; Length; Life; Life Style; Link; Measurement; Measures; Memory; Metabolic; Methods; Metric; Monitor; Movement; Output; Oxygen; Pattern; Pattern Recognition; Physical activity; Positioning Attribute; Public Health; Recommendation; Recruitment Activity; Research; Research Design; Running; Schools; Science; Signal Transduction; Source; Speed; Statistical Models; Techniques; Technology; Testing; Time; Touch sensation; Translating; Variant; Walking; base; boys; design; experience; girls; heuristics; improved; instrument; instrumentation; interest; markov model; novel; programs; public health relevance; real world application; sex; trend; uptake; user-friendly

DESCRIPTION (provided by applicant): Cadence-Kids is an R21 exploratory/developmental study designed to 1) measure and link cadence (steps/minute) to intensity cut points across age in 6-20 year olds, and 2) describe children's and adolescents' behavior in free-living using these cut points. Cadence is just one of the temporal-spatial parameters of gait. Cadence multiplied by stride length equals speed. Capture and expression of physical activity in terms of cadence represents an overlooked opportunity to examine free-living patterns of ambulatory intensity. To achieve our primary aim, we will identify and recruit 10 children and adolescents (5 boys, 5 girls) from each age-year between 6-20 years (a span of 10 age-years for a total of 150 children and adolescents) to a lab- based study of cadence (assessed on a treadmill) followed by a week-long free-living study of habitual physical activity. Under laboratory conditions we will calibrate different treadmill cadences with indirect calorimetry. We will subsequently monitor these same individuals' habitual minute-by-minute cadence for one week. We hypothesize that children's intensity will increase as cadence increases in a linear or nonlinear fashion such that we will be able to develop novel statistical models for predicting markers (cut points) of intensity from cadence. We further hypothesize that free-living estimates of children's time in at least moderate intensity activity will be higher using sex and age-calibrated cadence results compared to that obtained from more generic activity count cut points. We are uniquely positioned at the Pennington Biomedical Research Center to successfully conduct Cadence Kids as designed in a 2-year time period. We have established recruiting methods, excellent connections with schools and the community, and are fully experienced in exercise testing and accelerometry. The information derived from this R21 exploratory/developmental study will inform future R01 investigations related to cadence as an indicator of intensity in determining healthful levels of children's free-living physical activity. If successful, we expect that cadence cut points will be used both to assess ambulatory intensity, but also to inform program design focused on increasing not only the volume of physical activity (e.g., steps/day) but also its intensity (e.g., cadence) in user-friendly metrics.

描述（由申请人提供）：Cadence-Kids 是一项 R21 探索性/发展性研究，旨在 1) 测量 6-20 岁年龄段的步频（步数/分钟）并将其与强度削减点联系起来，2) 描述儿童和青少年的情况' 使用这些切点进行自由生活的行为。步频只是步态的时空参数之一。步频乘以步幅等于速度。以节奏来捕捉和表达身体活动代表了一个被忽视的检查自由生活的行走强度模式的机会。为了实现我们的主要目标，我们将确定并招募 10 名儿童和青少年（5 名男孩，5 名女孩） 从 6 至 20 岁之间的每个年龄段（总共 150 名儿童和青少年，共 10 个年龄段）到基于实验室的节奏研究（在跑步机上评估），然后进行为期一周的自由生活习惯性身体活动的研究。在实验室条件下我们将校准 不同的跑步机节奏与间接测热法。随后，我们将在一周内监测这些人的习惯性每分钟节奏。我们假设儿童的强度会随着节奏以线性或非线性方式增加而增加，这样我们将能够开发新的统计模型来预测节奏强度的标记（切点）。我们进一步假设，与通过更通用的活动计数切点获得的结果相比，使用性别和年龄校准的节奏结果对儿童至少在中等强度活动中的时间进行自由生活的估计将会更高。我们在彭宁顿生物医学研究中心拥有独特的地位，能够在 2 年时间内成功开展 Cadence Kids 的设计。我们建立了招募方法，与学校和社区建立了良好的联系，并且在运动测试和加速度测量方面拥有丰富的经验。从这项 R21 探索性/发展性研究中获得的信息将为未来与节奏相关的 R01 调查提供信息，作为确定儿童自由生活身体活动的健康水平的强度指标。如果成功，我们预计步频切点将不仅用于评估步行强度，而且还为计划设计提供信息，重点不仅是增加体力活动量（例如，步数/天），而且还包括其强度（例如， 节奏）以用户友好的指标。