Efficiency of Various Devices and Theories to Collect Nanoparticles Directly onto

直接收集纳米颗粒的各种设备和理论的效率

• 批准号: 9282836
• 负责人: Candace SuJung Tsai
• 金额: $ 6.48万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-02 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9282836
• 关键词: Efficiency; Various; Devices; Theories; Collect

DESCRIPTION (provided by applicant): Transmission electron microscope (TEM) is a very useful technique for evaluating nanoparticle morphology, for elemental analysis, and for particle counting and sizing. This technique has recently become a required tool to characterize exposure to airborne nanoparticles. The specific aim of this proposed research is to compare the available methods using TEM diffusive sampler (TDS), electrostatic precipitation sampler (EPS) and thermophoretic sampler (TPS) for directly depositing airborne engineered nanoparticles (ENPs) onto grids for material characterization. Research objectives include: comparison of size distributions, deposition uniformity and the ease of use. Test nanoparticle aerosols will be generated and samples will be collected side-by-side with three devices using each method, along with the NanoScan SMPS (TSI Model 3910, 10-420 nm) and Optical Particle Counter (OPC) (TSI Model 3330, 300 nm- 10 �m) to record the particle concentration. Experiments will be performed in the Birck Nanotechnology cleanroom laboratory at Purdue University. This research will test the following hypotheses: (1) Basic aerosol theory can be used to predict particle collection onto TEM grids; (2)TPS is more efficient than TDS and EPS for collecting particles less than 200 nm directly onto a TEM grid, EPS is more efficient than TPS and TDS for collecting particles from 200 nm - 10 �m, and none of the techniques are efficient at collecting particles larger than 1 �m; and (3) Nanoparticles collected by all three mechanisms are randomly distributed across a grid surface. The results from this research will provide informative technical results to develop the adequate use of samplers for collecting nanoparticles. In addition, the results will provide the input for further modifications to existin samplers or the development of a newly-designed sampler which can provide better performance for future research.

描述（由适用提供）：传输电子显微镜（TEM）是一种非常有用的技术，用于评估纳米颗粒形态，用于元素分析以及粒子计数和尺寸。最近，该技术已成为表征暴露于机载纳米颗粒的必需工具。这项拟议的研究的具体目的是使用TEM差异采样器（TDS），静电沉淀采样器（EPS）和热疗法采样器（TPS）比较可用的方法，以直接沉积空气中的工程纳米颗粒（ENP）（ENPS）到网格上以进行材料表征。研究对象包括：大小分布，沉积均匀性和易用性的比较。将生成测试纳米颗粒气雾剂，并使用每种方法与三种设备并排收集样品，以及纳米SMP（TSI模型3910，10-420 nm）和光学粒子计数器（OPC）（TSI 3330，3330，300 nm-10 mm-10 mm），以记录颗粒浓度。实验将在普渡大学的Birck纳米技术清洁室实验室进行。这项研究将检验以下假设：（1）基本的气溶胶理论可用于预测粒子在TEM网格上的收集； （2）TPS比将小于200 nm的颗粒直接收集到TEM网格的TDS和EPS更有效，EPS比从200 nm -10 m -10 m收集颗粒的TPS和TDS效率更高，并且这些技术在收集大于1.m的颗粒方面都不是有效的； （3）通过所有三种机制收集的纳米颗粒均随机分布在网格表面上。这项研究的结果将提供信息丰富的技术结果，以开发适当使用样品来收集纳米颗粒。此外，结果将为现有样本或新设计的采样器的开发提供进一步修改的输入，该样本可以为将来的研究提供更好的性能。