Maintaining Cognitive Health in Aging Veterans

保持老年退伍军人的认知健康

• 批准号: 8634918
• 负责人: Maureen Katheleen O'Connor
• 金额: --
• 依托单位: EDITH NOURSE ROGERS MEMORIAL VETERANS HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-02-01 至 2016-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8634918
• 关键词: Activities of Daily Living; Affective; Age; Age Factors; Aging; Aging-Related Process; Alzheimer disease prevention; Alzheimer' s Disease; American; Anxiety; Appointment; Attitude; Belief; Brain; Caring; Centers for Disease Control and Prevention (U.S.); Clinic; Clinical; Clinical Services; Clinical Trials Design; Cognition; Cognition Disorders; Cognitive; Cognitive aging; Complex; Control Groups; Dementia; Diagnosis; Distress; Education; Effectiveness; Elderly; Emotional; Evaluation; Fright; Goals; Happiness; Health; Health Personnel; Hour; Impaired cognition; Intervention; Intervention Studies; Investigation; Knowledge; Life; Literature; Measures; Memory; Mental Depression; Mental Health; Minor; National Institute of Neurological Disorders and Stroke; Neuropsychological Tests; Occupational; Older Population; Outcome; Outcome Measure; Perception; Performance; Population; Prospective Studies; Psychological Factors; Psychological Transfer; Questionnaires; Randomized; Randomized Controlled Trials; Recommendation; Research Personnel; Risk Factors; Signal Transduction; Sleep; Social Welfare; Specificity; Staging; Time; Training; Veterans; Well in self; Work; age related; cognitive change; cognitive function; cognitive training; design; diet and exercise; effective intervention; emotional distress; follow-up; functional outcomes; group intervention; health administration; improved; informant; intervention effect; lifestyle factors; mild cognitive impairment; multi-component intervention; normal aging; pathological aging; prevent; psychoeducation; psychological distress; psychological outcomes; public health relevance; response; skills; skills training; social

DESCRIPTION (provided by applicant): The proportion of Veterans over age 65 has risen from 11% to 26% from 1980 to 1990, and is estimated to rise to over 50% by 2030 (Hisnanik, 1994). Due to the growing number of older Veterans, health issues specific to the aging Veteran population is a primary concern for the Veterans Health Administration. Fear of developing dementia is common among older adults (Commisseris, Ponds, & Jollees, 1998; Corner & Bond, 2004) and minor memory lapses that were previously of little concern may be misinterpreted as signaling the beginning stages of dementia (Commissaris et al., 1994). Although normal cognitive aging is not the same as pathological aging, the impact of normal age-related changes warrants intervention since it can cause emotional distress and functional difficulties impacting occupational, recreational, and social pursuits (Royall et al., 2004, 2005; Dodge et al., 2008) and subjective cognitive impairment, defined as a noticed cognitive change without objective evidence of decline on neuropsychological testing may be the earliest precursor for dementia (Reisberg, et al., 2010). While cognitive changes can be expected as we age, there is a growing body of literature demonstrating that modifiable lifestyle factors can influence functional ability and quality of lif as one ages (Depp, Vahia, & Jeste, 2010; LaRue, 2010). In addition, cognitive training may result in improvements in cognition and functioning in older adults (Unverzagt et al., 2009; Papp et al., 2009; Lustig et al., 2009). Unfortunately, many older adults lack knowledge about cognitive aging and the factors that contribute to successful cognitive aging, which limits their ability to make changes that can improve the odds of successful cognitive aging (Anderson et al., 2009). The need to disseminate information related to brain health has recently been recognized by key agencies involved in promoting the welfare of older adults, including the National Institutes of Neurological Disorders and Stroke, Mental Health, and Aging (the Cognitive and Emotional Health Project; Hendrie et al., 2006) as well as the Centers for Disease Control and Prevention and the Alzheimer's Association (the Healthy Brain Initiative; 2007). The current study builds upon previous work on cognitive intervention in older adults by investigating a multi-component intervention which includes psychoeducation about cognitive aging, presentation of lifestyle factors that contribute to successful cognitive aging, and broad cognitiv skills training. Using a randomized controlled trial design, 72 Veterans will be assigned to either the intervention group (36) or a no treatment control group (36). Veterans will undergo baseline assessment, which will be used for comparison immediately following the intervention and at 3 and 6 month follow- up. Outcomes include knowledge of cognitive aging, measures of psychological wellness, and indicators of cognitive and functional ability.

描述（由申请人提供）： 从 1980 年到 1990 年，65 岁以上退伍军人的比例从 11% 上升到 26%，预计到 2030 年将上升到 50% 以上（Hisnanik，1994）。由于老年退伍军人数量不断增加，老龄化退伍军人人口特有的健康问题是退伍军人健康管理局的主要关注点。对患上痴呆症的恐惧在老年人中很常见（Commisseris, Ponds, & Jollees, 1998；Corner & Bond, 2004），以前很少关注的轻微记忆衰退可能会被误解为痴呆症开始阶段的信号（Commissaris et al. 2004）。 ，1994）。尽管正常的认知衰老与病理性衰老不同，但与年龄相关的正常变化的影响值得干预，因为它可能导致情绪困扰和功能困难，影响职业、娱乐和社会追求（Royall等人，2004年，2005年；Dodge）等人，2008）和主观认知障碍，定义为注意到的认知变化，但没有神经心理学测试下降的客观证据，可能是痴呆症的最早前兆（Reisberg，等人， 2010）。虽然随着年龄的增长，认知能力会发生变化，但越来越多的文献表明，随着年龄的增长，可改变的生活方式因素可以影响功能能力和生活质量（Depp、Vahia 和 Jeste，2010 年；LaRue，2010 年）。此外，认知训练可能会改善老年人的认知和功能（Unverzagt 等，2009；Papp 等，2009；Lustig 等，2009）。不幸的是，许多老年人缺乏关于认知老化和有助于成功认知老化的因素的知识，这限制了他们做出改变以提高成功认知老化几率的能力（Anderson等，2009）。最近，参与促进老年人福利的主要机构认识到传播与大脑健康相关的信息的必要性，其中包括美国国家神经疾病和中风、心理健康和老龄化研究所（认知和情绪健康项目；Hendrie 等） al.，2006）以及疾病控制与预防中心和阿尔茨海默病协会（健康大脑倡议；2007）。目前的研究建立在以前对老年人认知干预的研究基础上，通过调查多成分干预措施，其中包括关于认知衰老的心理教育、介绍有助于成功认知衰老的生活方式因素以及广泛的认知技能培训。使用随机对照试验设计，72 名退伍军人将被分配到 干预组（36）或无治疗对照组（36）。退伍军人将接受基线评估，该评估将在干预后立即以及 3 个月和 6 个月的随访中用于比较。结果包括认知衰老知识、心理健康测量以及认知和功能能力指标。