Delaware/Christiana Care Community Clinical Oncology Program

特拉华州/克里斯蒂安娜护理社区临床肿瘤学计划

基本信息

批准号：
8850965
负责人：
Stephen S. Grubbs
金额：
$ 23.73万
依托单位：
CHRISTIANA CARE HEALTH SERVICES, INC.
依托单位国家：
美国
项目类别：
财政年份：
1987
资助国家：
美国
起止时间：
1987-08-05 至 2014-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8850965
关键词：
Advocate American Society of Clinical Oncology Awareness Cancer Control Cancer Control Research Cancer and Leukemia Group B Caring Catchment Area Clinical Clinical Research Clinical Trials Commit Communities Community Clinical Oncology Program Controlled Study County Data Delaware Discipline Disease Doctor of Medicine Eastern Cooperative Oncology Group Ensure Funding Goals Grant Gynecologic Oncology Group Health Services Health Services Accessibility Health system Hospitals Human Resources Incidence Individual Investigational Drugs Leadership Malignant Neoplasms Maryland Mission Morbidity - disease rate National Surgical Adjuvant Breast and Bowel Project New Jersey Outcome Participant Pediatric Hospitals Pennsylvania Population Positioning Attribute Prevention Principal Investigator Process Protocols documentation Quality of life Radiation Therapy Oncology Group Research Research Methodology Research Personnel Role Time Underrepresented Minority Work anticancer research base cancer prevention cancer site cancer therapy data management forest improved mortality outreach population based programs quality assurance treatment trial

项目摘要

Delaware/Christiana Care CCOP was originally funded by the NCI in 1987 and has continued to be an exemplary participant since that time. Currently, CALGB, NSABP, ECOG, RTOG, GOG, COG, Wake Forest, URCC and CTSU are utilized as research bases. ACOS-OG trials have also been accessed although not through the CCOP mechanism. Our extensive catchment area includes all of Delaware and portions of New Jersey, northeastern Maryland and southeastern Pennsylvania (Delaware and Chester counties). Delaware ranks 3rd in the nation for all cancer site disease incidence, Maryland ranks 35th, New Jersey 5th and Pennsylvania 6th (2007 USCS Data). Our research base represents a population base in excess of 2 million people with extensive protocol entry potential. Under the leadership of Stephen S.Grubbs, M.D., Principal Investigator and Kandie Dempsey, MS, RN, OCN, Director, CCOP investigators, project coordinators and data managers will continue to participate in cooperative group core committees and leadership positions. Our mission is to continue accruals to both treatment and cancer control studies. In addition, CCHS is committed to having personnel continue to provide significant contributions in leadership roles on cooperative group core committees and as cooperative group protocol study chairs. The overall impact of this grant will be to ensure continuation and stimulate expansion of CCOP activities, including treatment and cancer control research, at Christiana Care Health Services and its affiliates throughout the catchment area.

特拉华州/克里斯蒂安娜（Christiana Care CCOP）最初是由NCI资助的自那时以来的示例参与者。目前，CALGB，NSABP，ECOG，RTOG，GOG，COG，WAKE 森林，URCC和CTSU被用作研究基础。 ACOS-og试验也已访问尽管不是通过CCOP机制。我们广泛的集水区包括特拉华州和新泽西州，马里兰州东北部和宾夕法尼亚州东南部的部分地区（特拉华州和切斯特县）。特拉华州在所有癌症现场疾病发病率的全国排名第三，马里兰州排名第35 泽西岛第五和宾夕法尼亚州第6（2007年USCS数据）。我们的研究基础代表了人口基础超过200万人具有广泛的协议进入潜力。在斯蒂芬的领导下 S.Grubbs，M.D。，首席研究员和坎迪·登普西（Kandie Dempsey）项目协调员和数据经理将继续参加合作集团核心委员会和领导职位。我们的任务是继续进行治疗和癌症控制研究。此外，CCHS致力于让人员继续为领导在合作小组核心委员会和合作小组协议研究主持人中的角色。总体这笔赠款的影响将是确保继续并刺激CCOP活动的扩展，包括克里斯蒂安娜（Christiana Care Health Services）及其分支机构的治疗和癌症控制研究集水区。

项目成果

期刊论文数量（13）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

DOI：
10.1002/cncr.24140
发表时间：
2009-03-01
期刊：
CANCER
影响因子：
6.2
作者：
Paskett, Electra;Herndon, James, II;Donohue, Kathleen;Naughton, Michelle;Grubbs, Stephen;Pavy, Michael;Hensley, Martee;Stark, Nancy;Kornblith, Alice;Bittoni, Marisa
通讯作者：
Bittoni, Marisa

Comparative analysis of NFAT (nuclear factor of activated T cells) complex in human T and B lymphocytes.

人 T 和 B 淋巴细胞中 NFAT（活化 T 细胞核因子）复合物的比较分析。

DOI：
发表时间：
1993
期刊：
The Journal of biological chemistry
影响因子：
0
作者：
Yaseen,NR;Maizel,AL;Wang,F;Sharma,S
通讯作者：
Sharma,S

Sentinel node staging of resectable colon cancer: results of a multicenter study.

可切除结肠癌的前哨淋巴结分期：多中心研究的结果。

DOI：
10.1097/01.sla.0000140753.41357.20
发表时间：
2004
期刊：
Annals of surgery
影响因子：
9
作者：
Bertagnolli,Monica;Miedema,Brent;Redston,Mark;Dowell,Jeannette;Niedzwiecki,Donna;Fleshman,James;Bem,Jiri;Mayer,Robert;Zinner,Michael;Compton,Carolyn
通讯作者：
Compton,Carolyn

Loss of transforming growth factor beta 1 receptors and its effects on the growth of EBV-transformed human B cells.

转化生长因子 β1 受体的丧失及其对 EBV 转化的人类 B 细胞生长的影响。