Sensorimotor Training to Affect Balance, Engagement and Learning in Children with

感觉运动训练可影响儿童的平衡、参与和学习

基本信息

  • 批准号:
    8526293
  • 负责人:
  • 金额:
    $ 19.24万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2009
  • 资助国家:
    美国
  • 起止时间:
    2009-09-30 至 2014-11-30
  • 项目状态:
    已结题

项目摘要

Project Summary / Abstract RFA-MH-09-161: Novel Interventions for Neurodevelopmental Disorders R21/R33 Prenatal exposure to alcohol can increase the risk for lifelong neurobehavioral problems, as well as developmental disabilities that fall under the umbrella term of fetal alcohol spectrum disorders (FASD). Poor sensorimotor function, specifically balance deficits, is one area of neurodevelopmental impairment described among children with FASD. Efficient balance and postural control are important foundations for engagement in higher level functional skills such as maintaining attention, navigating an environment, controlling complex movements, and participating in childhood activities that promote physical and behavioral health and development. Balance is a complex process involving the integration sensory information and the coordination of neuromuscular responses. Despite evidence that balance deficits are problematic among children with FASD and preliminary reports that poor sensorimotor integration is suspect, the nature of these balance and postural control deficits are not fully understood. Nor have interventions to improve daily function and behavior through the remediation of underlying sensorimotor deficits been considered and tested among this population, Yet, evidence from alcohol exposed animal models indicates the capacity for neural plasticity, motor learning, and improved motor performance following complex rehabilitative training. Therefore, the overarching goal of this combined R21/R33 proposal is to determine the preliminary effectiveness of a sensorimotor intervention to improve balance and related functional and behavioral outcomes among children with FASD. Our proposed intervention will employ the use of virtual reality computer technology to train the ability to weight and reweight sensory information during balance perturbations invoked by simulated conditions of sensory conflict. As a first step, this research (R21) proposes to more fully describe balance impairments and subsequent functional impact of sensorimotor problems in children with FASD. This will be done by comparing the performance of children with FASD ages 7.0-14.9 years to a matched group of children with typical development on a battery of clinical tests and a novel assessment system that specifically examines how visual, vestibular and somatosensory information is used during balance. This data will shape the development of our proposed sensorimotor intervention technology and preliminary intervention protocol, which will be tested with a small group of children with FASD to gauge initial feasibility and responsiveness. Data from the R21 will lay the groundwork for the next phase of research (R33) that aims to refine the sensorimotor training for balance intervention technology and establish and test the effectiveness of the intervention delivered via a short-term intensive laboratory protocol or a longer term home-based protocol. Collectively, these studies lay the essential groundwork for a larger multisite efficacy study to determine the effectiveness of the intervention with a larger sample of children with FASD and other groups of children with neurodevelopmental disabilities.
项目摘要 /摘要 RFA-MH-09-161:神经发育障碍的新颖干预措施R21/R33 产前暴露于酒精会增加终身神经行为问题的风险 发育障碍属于胎儿酒精谱系障碍(FASD)的伞。贫穷的 感觉运动功能,特别是平衡缺陷,是描述的神经发育障碍的一个领域 在有FASD的孩子中。有效的平衡和姿势控制是参与的重要基础 更高级别的功能技能,例如保持注意力,导航环境,控制复合物 运动,并参与促进身体和行为健康的童年活动, 发展。平衡是一个复杂的过程,涉及集成感官信息和协调 神经肌肉反应。尽管有证据表明平衡不足是有问题的 FASD和初步报告说,感觉不良的整合是可疑的,这些平衡的性质和 姿势控制缺陷尚未完全理解。也没有干预措施来改善日常功能和行为 通过修复潜在的感觉运动缺陷,并在该人群中进行了测试, 然而,酒精暴露的动物模型的证据表明神经可塑性,运动学习, 并在复杂的康复训练后改善了运动性能。因此,总体目标 该组合的R21/R33建议是确定感觉运动干预的初步效率 改善FASD儿童的平衡以及相关的功能和行为结果。我们提出的 干预将利用虚拟现实计算机技术来训练重量和重量的能力 在平衡扰动过程中,感官信息是通过感觉冲突的模拟条件引用的。首先 步骤,这项研究(R21)建议更充分地描述平衡障碍和随后的功能 感觉运动问题对FASD儿童的影响。这将通过比较 FASD年龄在7.0-14.9岁的FASD的儿童,与一组典型的电池开发的儿童 临床测试和新的评估系统,该系统专门研究视觉,前庭和 平衡期间使用体感信息。这些数据将塑造我们提议的开发 感觉运动干预技术和初步干预方案,将通过少量测试 一组FASD的儿童以衡量最初的可行性和响应能力。 R21的数据将放置 下一阶段研究的基础(R33),旨在完善感觉运动训练以保持平衡 干预技术并建立和测试通过短期提供的干预措施的有效性 密集实验室协议或长期家庭协议。总的来说,这些研究是必不可少的 大型多站点功效研究的基础工作,以确定干预措施的有效性 患有FASD的儿童和其他神经发育残疾儿童的样本。

项目成果

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TRACY L JIRIKOWIC其他文献

TRACY L JIRIKOWIC的其他文献

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{{ truncateString('TRACY L JIRIKOWIC', 18)}}的其他基金

Sensorimotor Training to Affect Balance, Engagement and Learning in Children with
感觉运动训练可影响儿童的平衡、参与和学习
  • 批准号:
    7941997
  • 财政年份:
    2009
  • 资助金额:
    $ 19.24万
  • 项目类别:
Sensorimotor Training to Affect Balance, Engagement and Learning in Children with
感觉运动训练可影响儿童的平衡、参与和学习
  • 批准号:
    8290692
  • 财政年份:
    2009
  • 资助金额:
    $ 19.24万
  • 项目类别:
Sensorimotor Training to Affect Balance, Engagement and Learning in Children with
感觉运动训练可影响儿童的平衡、参与和学习
  • 批准号:
    8320854
  • 财政年份:
    2009
  • 资助金额:
    $ 19.24万
  • 项目类别:

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