Archiving Additional Waves of the Swedish Adoption/Twin Study of Aging (SATSA)

归档瑞典收养/双胞胎老龄化研究 (SATSA) 的其他浪潮

基本信息

批准号：
8368292
负责人：
NANCY L PEDERSEN
金额：
$ 5.4万
依托单位：
KAROLINSKA INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-08-01 至 2013-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8368292
关键词：
Activities of Daily Living Address Adoption Adult Age Aging Aging-Related Process Archives Behavioral Behavioral Genetics California Cognition Cognitive Collaborations Communities Complex Confidentiality Data Data Analyses Data Collection Data Files Data Set Deposition Development Documentation Educational workshop Elderly Emotional Ensure Florida Foundations Funding Genetic Genetic Risk Gerontology Grant Half-Life Health behavior Impaired cognition Indiana Individual Institutes Institution Knowledge Life Style Linear Models Longitudinal Studies Los Angeles Mails Measurement Measures Meta-Analysis Michigan Minnesota Mission NIH Program Announcements National Institute on Aging Occupational Outcome Participant Patient Self-Report Pennsylvania Personal Satisfaction Personality Persons Phenotype Physical Function Probability Process Psychosocial Stress Public Health Questionnaires Registries Research Research Personnel Resources Sample Size Sampling Social Environment Social Impacts Socioeconomic Status Source Sweden Testing Twin Multiple Birth Twin Studies United States National Institutes of Health Universities Virginia Well in self West Virginia Work aged cognitive function computerized data modeling experience healthy aging improved interest lifestyle factors member physical conditioning psychologic ranpirnase resilience response social socioeconomics trait user-friendly

项目摘要

DESCRIPTION (provided by applicant): The purpose of the work described in this application is to archive the Swedish Adoption/Twin Study of Aging (SATSA) data collected by NIH Grant No. R01AG10175 with the Inter-University Consortium for Political and Social Research (ICPSR) and in collaboration with the National Archive of Computerized Data on Aging (NACDA) at the University of Michigan. Data archiving serves the purpose of enabling other investigators to make use of this resource, both by itself and in multi-study efforts across different studies with similar information. Increasing the availability of these data may facilitat additional harmonization activities, as highlighted in NIA harmonization workshops in Los Angeles (May 2011) and Bethesda (November 2011). The archiving activities described here entail converting the complex questionnaire and in-person testing data into controlled access public use files with user-friendly formats that facilitate data use. SATSA includes multiple longitudinal waves of assessment of cognitive functioning, physical health, and well-being, via both self-report questionnaire (Q) and in-person testing (IPT). Previously, the first 4 questionnaire waves and the first 3 waves of in-person testing have been archived at the ICPSR. The data archiving proposed here adds 2 more Q waves and 2 more IPT waves, and would make available data from 2174 participants with up to 6 waves of questionnaire data and from a subset of 859 individuals aged 50 and older with up to 5 in-person assessments. Whereas 3 waves of assessment are adequate to support modeling linear changes with age, 5 waves of assessment provide sufficient data for modeling more complex trajectories of change with age: accelerating decline and multiple change points. Assessment in multiple domains allows for testing cross-domain relationships. Importantly, adding 2 more waves of IPT and Q data to the data archive increases the proportion of the sample that has participated in at least 3 waves of measurement. The activities described in this application include formatting datasets and creating documentation consistent with ICPSR standards. Direct identifiers are already removed; in the course of preparing data files for archiving, we will further de-identify the data o protect the confidentiality of participants. The completed SATSA data archive thus has a potential to address many secondary analysis questions concerning psychological and social processes in aging and the behavior genetics of aging. PUBLIC HEALTH RELEVANCE: Data archiving is encouraged by NIH as a way to make data as widely and freely available as possible to the research community while safeguarding the confidentiality of participants. Those participating in the original study were motivated to contribute to knowledge about the aging process and sources of cognitive decline in older adults. Archiving serves the aspirations of those participants and the interests of public health by permitting the fullest possible use of the information that was collected. The research questions that can be addressed by those using the data archive are of intense public interest, namely, discovering potentially modifiable lifestyle factors and health behaviors that improve the probability for maintaining functioning across domains in old age.

描述（由申请人提供）：本申请中描述的工作的目的是存档由 NIH 拨款号 R01AG10175 与大学间政治和社会研究联盟 ( ) 收集的瑞典收养/双胞胎老龄化研究 (SATSA) 数据。 ICPSR）并与密歇根大学国家老龄化计算机化数据档案馆（NACDA）合作。数据归档的目的是使其他研究人员能够利用该资源，无论是单独使用还是在具有相似信息的不同研究的多项研究工作中使用。正如在洛杉矶（2011 年 5 月）和贝塞斯达（2011 年 11 月）举行的 NIA 协调研讨会所强调的那样，增加这些数据的可用性可能会促进额外的协调活动。这里描述的归档活动需要将复杂的调查问卷和现场测试数据转换为受控访问的公共使用文件，这些文件具有用户友好的格式，便于数据使用。 SATSA 包括通过自我报告问卷 (Q) 和现场测试 (IPT) 对认知功能、身体健康和幸福感进行多次纵波评估。此前，前 4 波问卷调查和前 3 波现场测试已在 ICPSR 存档。这里提出的数据归档增加了 2 个 Q 波和 2 个 IPT 波，并将提供来自 2174 名参与者的数据（最多 6 波问卷数据）以及来自 859 名 50 岁及以上个人的子集（最多 5 次现场调查）的数据评估。虽然 3 波评估足以支持对随年龄的线性变化进行建模，但 5 波评估提供了足够的数据来建模更复杂的随年龄变化的轨迹：加速衰退和多个变化点。多个域中的评估允许测试跨域关系。重要的是，在数据存档中再添加 2 波 IPT 和 Q 数据会增加参与至少 3 波的样本比例测量波。此应用程序中描述的活动包括格式化数据集和创建符合 ICPSR 标准的文档。直接标识符已被删除；在准备数据文件归档的过程中，我们将进一步对数据进行去标识化处理，保护参与者的机密。因此，完整的 SATSA 数据档案有可能解决许多有关衰老的心理和社会过程以及衰老行为遗传学的二次分析问题。公共卫生相关性：NIH 鼓励数据归档，以此作为向研究界尽可能广泛、免费提供数据的一种方式，同时保护参与者的机密性。参与最初研究的人有动力为了解衰老过程和老年人认知能力下降的根源做出贡献。归档通过允许尽可能充分地使用所收集的信息来满足这些参与者的愿望和公共健康的利益。使用数据档案的人可以解决的研究问题引起了公众的强烈兴趣，即发现潜在的可改变的生活方式因素和健康行为，以提高在老年时维持跨领域功能的可能性。