SEQUENCE DETERMINANTS OF PROTEIN STRUCTURE AND FUNCTION

蛋白质结构和功能的序列决定因素

• 批准号: 8169212
• 负责人: Robert T Sauer
• 金额: $ 0.52万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169212
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Enzymes; Funding; Grant; Institution; Proteins; Research; Research Personnel; Resources; Source; United States National Institutes of Health; protein structure function

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are studying how AAA+ enzymes including ClpXP, HslUV, and Lon catalyze ATP-dependent denaturation and subsequent degradation of specific target proteins.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 我们正在研究 AAA+ 酶（包括 ClpXP、HslUV 和 Lon）如何催化 ATP 依赖性变性以及随后特定靶蛋白的降解。