FASEB SRC on Epigenetics, Chromatin & Transcription

FASEB SRC 表观遗传学、染色质

• 批准号: 8525736
• 负责人: RAMIN SHIEKHATTAR
• 金额: $ 0.5万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-15 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8525736
• 关键词: Address; Aging; Area; Bahamas; Biology; Cells; Chromatin; Chromatin Structure; Collaborations; DNA Packaging; DNA Sequence; Development; Developmental Biology; Discipline; Disease; Environmental Exposure; Epigenetic Process; Fostering; Functional RNA; Funding; Gene Expression; Gene Expression Regulation; Genetic Transcription; Genome; Genomics; Goals; Heritability; Inherited; International; Lead; Malignant Neoplasms; Molecular Profiling; Organism; Postdoctoral Fellow; Predisposition; Process; Proteins; Reading; Research; Research Personnel; Scientist; Signal Transduction; Specificity; Stem cells; System; Therapeutic Intervention; abstracting; cell type; cohort; environment related cancer; fundamental research; interest; medical specialties; meetings; novel; protein expression; public health relevance; response; symposium

DESCRIPTION (provided by applicant): This application seeks partial funding for a FASEB Summer Conference on "Epigenetics Chromatin & Transcription", to be held June 16-21, 2013 in Nassau, Bahamas. The major goal of this conference is provide a forum to bring together several disciplines addressing the epigenetic changes that occur across the genome in response to signals (developmental and environmental) and in disease. This meeting will provide a much needed venue for researchers whose interests converge on these important questions, so that they can review key developments in this growing field, and to foster and inspire new research directions. Importantly, epigenetic research encompasses a wide diversity of specialties, ranging from those studying the fundamental biology underlying epigenetic inheritance to those focusing on the influences of intra- and extra-cellular signals. This meeting is unique in endeavoring to bring together these multiple aspects. From its inception in 1991, this FASEB conference has regularly attracted a strong international group of attendees and speakers, and, indeed, is one of the most consistently successful FASEB meetings. Moreover, to reflect this dynamic field, the focus of the meeting continually evolves. This year, we are emphasizing genomic approaches to understanding how transient signals can lead to persistent chromatin regulatory states in both the normal development of an organism and in disease. In addition, to expand the interest area, we have included a new cohort of speakers focusing on non-coding RNAs and their influence on chromatin and epigenetic features of the genome. Finally, we plan to markedly diversify the speaker group by selecting 8-12 additional speakers, especially promising post-doctoral scientists, from abstracts. The specific objectives of the meeting are: 1.To provide a comprehensive and critical review of the field of epigenetic regulation of gene expression. The meeting extends from basic biology of epigenetic heritability into other key areas, such as genomic and systems approaches, non-coding RNAs, windows of susceptibility (e.g. developmental biology and the use of stem cells), as well as disease areas (e.g. environmental exposures and cancer). 2. To advance cutting-edge research in this expanding field, through presentation and lively discussion of novel breakthroughs. 3. To bring together senior and junior scientists of all ranks, encouraging wide- ranging discussions and promoting the development of young scientists.

描述（由申请人提供）：本申请为将于 2013 年 6 月 16 日至 21 日在巴哈马拿骚举行的 FASEB 夏季会议“表观遗传学染色质和转录”寻求部分资助。本次会议的主要目标是提供一个论坛，将多个学科聚集在一起，讨论基因组中响应信号（发育和环境）和疾病而发生的表观遗传变化。这次会议将为那些对这些重要问题感兴趣的研究人员提供一个急需的场所，以便他们能够回顾这个不断发展的领域的关键进展，并培育和启发新的研究方向。重要的是，表观遗传学研究涵盖了广泛的专业领域，从研究表观遗传基础生物学的研究到关注细胞内和细胞外信号影响的研究。这次会议的独特之处在于努力将这些多个方面结合在一起。自 1991 年召开以来，本次 FASEB 会议定期吸引了众多国际与会者和演讲者，事实上，它是最持续成功的 FASEB 会议之一。此外，为了反映这个动态领域，会议的焦点不断变化。今年，我们强调基因组方法来了解瞬态信号如何在生物体的正常发育和疾病中导致持久的染色质调节状态。此外，为了扩大兴趣领域，我们邀请了一批新的演讲者，重点关注非编码 RNA 及其对染色质和基因组表观遗传特征的影响。最后，我们计划通过从摘要中选择 8-12 位额外的演讲者，特别是有前途的博士后科学家，使演讲者群体显着多样化。会议的具体目标是： 1.对基因表达的表观遗传调控领域进行全面和批判性的回顾。会议从表观遗传性的基础生物学扩展到其他关键领域，例如基因组和系统方法、非编码RNA、易感性窗口（例如发育生物学和干细胞的使用）以及疾病领域（例如环境暴露）和癌症）。 2. 通过对新突破的展示和热烈讨论，推进这一不断扩展的领域的前沿研究。 3. 汇聚各级高级和青年科学家，鼓励广泛讨论，促进青年科学家的发展。