Cap snatching mechanism of arenaviruses

沙粒病毒的抢帽机制

• 批准号: 8293447
• 负责人: Hinh Ly
• 金额: $ 2.35万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2011-10-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8293447
• 关键词: 3-Dimensional; Acute; Antiviral Agents; Arenavirus; Binding; Biochemical; Biological; Biological Assay; Cell Nucleus; Cells; Cellular Structures; Complex; Cytoplasm; Development; Disease; Divalent Cations; Endoribonucleases; Genetic Transcription; Goals; Human; In Vitro; Infection; Influenza; Knowledge; Laboratories; Lassa fever virus; Lassa virus; Lead; Life Cycle Stages; Mediating; Messenger RNA; Molecular; Molecular Cloning; Molecular Virology; Mutagenesis; Nucleic Acid Cleavage; Nucleoproteins; Nucleotides; Pichinde; Polymerase; Process; Protein Biochemistry; Proteins; RNA; RNA Caps; RNA Viruses; Replicon; Role; Structural Models; Structure; System; Theft; Therapeutic; Time; Vaccines; Viral; Viral Genome; Viral Hemorrhagic Fevers; Viral Physiology; Viral Proteins; Virus; Virus Diseases; Zinc; abstracting; base; effective therapy; endoribonuclease; in vitro activity; in vivo; influenzavirus; insight; mRNA Precursor; mRNA capping; novel; positional cloning; therapeutic development; therapeutic vaccine; viral RNA