Columbia University/Aga Khan University Global Network Research Unit

哥伦比亚大学/阿迦汗大学全球网络研究中心

基本信息

批准号：
8519731
负责人：
ROBERT L GOLDENBERG
金额：
$ 66.95万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-09-30 至 2018-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8519731
关键词：
Age Award Birth Caring Cellular Phone Cessation of life Child Child health care Childhood Clinics and Hospitals Collaborations Commit Communities Community Health Country Data Data Collection Data Quality Developing Countries Enrollment Environment Feedback Fetal Mortality Statistics Foundations Funding Goals Grant Growth and Development function Health Health Sciences Hospitals Income Industry Infant Institution International Intervention Intervention Trial Leadership Manuscripts Maternal Mortality Maternal and Child Health Mentors Mission Morbidity - disease rate Mothers Neonatal Mortality Newborn Infant Outcome Pakistan Participant Performance Perinatal Population Population Study Pregnancy Outcome Pregnant Women Preparation Principal Investigator Protocols documentation Quality of Care Recruitment Activity Registries Research Research Design Research Personnel Research Support Resources Rural Rural Population Senior Scientist Services Site Sum System Universities Urban Hospitals Urban Population Woman Women&apos s Health base follow-up improved intrapartum mortality neonatal death population based programs protocol development public health relevance quality assurance randomized trial research study stillbirth

Age Award Birth Caring Cellular Phone Cessation of life Child Child health care Childhood Clinics and Hospitals Collaborations Commit Communities Community Health Country Data Data Collection Data Quality Developing Countries Enrollment Environment Feedback Fetal Mortality Statistics Foundations Funding Goals Grant Growth and Development function Health Health Sciences Hospitals Income Industry Infant Institution International Intervention Intervention Trial Leadership Manuscripts Maternal Mortality Maternal and Child Health Mentors Mission Morbidity - disease rate Mothers Neonatal Mortality Newborn Infant Outcome Pakistan Participant Performance Perinatal Population Population Study Pregnancy Outcome Pregnant Women Preparation Principal Investigator Protocols documentation Quality of Care Recruitment Activity Registries Research Research Design Research Personnel Research Support Resources Rural Rural Population Senior Scientist Services Site Sum System Universities Urban Hospitals Urban Population Woman Women&apos s Health base follow-up improved intrapartum mortality neonatal death population based programs protocol development public health relevance quality assurance randomized trial research study stillbirth

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项目摘要

DESCRIPTION (provided by applicant): This application to the Global Network (GN) for Women's and Children's Research asks for the Global Network Research Unit of Aga Khan and Columbia Universities to be renewed for a third 5 year term. We believe that our track record, especially over the last 5 years, as documented in the full application, justifies an award for the next 5 years. The strengths of this application include a stable and highly productive team devoted to carrying out meaningful research to improve the health of women and children, large and varied populations for study, and an ongoing birth outcomes registry of 20 rural clusters of 500 deliveries per year each with excellent follow up. Pakistan, with a population of 180,000,000 people and some of the highest maternal, fetal and neonatal mortality rates anywhere in the world, provides every type of population that could be considered for GN studies. We have the largest number of rural clusters of any site in the GN with an active birth registry in each, and have also demonstrated access to a number of urban hospitals for deliveries and access to urban children for research purposes as well. To date we have recruited more than 220,000 subjects for GN studies. In the next 5 years, we plan to bring substantial external resources to the GN by building strong relationships between industry, foundations and the GN to do research meaningful to all three institutions. We will actively participate in the deliberations of the GN Steering Committee and continue to mentor more junior investigators at our site and other sites in the GN in research study design, and manuscript and grant preparation. One of our major goals is to improve facility performance in the care of mothers and infants. Our proposed common protocol alms to reduce facility fetal and neonatal mortality using a defined outcome related to facility care, e.g., the sum of intrapartum stillbirths and early (pre- discharg) neonatal deaths. Using a simple cellular telephone-based data collection system, rapid feedback on the defined outcome, and a quality assurance program aimed at reducing intrapartum related deaths; it is our hope to achieve a substantial improvement in facility-based pregnancy outcomes.

描述（由申请人提供）：针对妇女和儿童研究的全球网络（GN）申请要求将AGA Khan和哥伦比亚大学的全球网络研究部门续签第三年期。我们认为，正如完整申请中所记录的那样，我们的往绩，尤其是在过去的5年中，证明了奖励接下来的5年。该应用程序的优势包括一个稳定且高产的团队，致力于进行有意义的研究，以改善妇女和儿童的健康，大量和多样化的研究，以及每年有20个农村群集的持续分娩结果注册表，每年有500个送货，并进行了出色的随访。巴基斯坦，人口为180万人，世界上任何地方的母亲，胎儿和新生儿死亡率最高的人口都提供了所有类型的人口，可以考虑使用GN研究。我们拥有GN的任何地点的农村集群数量最多，每个地点都有活跃的出生注册表，并且还显示出了许多城市医院的送货服务，以送货和去城市儿童，以进行研究。迄今为止，我们已经招募了22万多名GN研究。在接下来的5年中，我们计划通过在行业，基金会和GN之间建立牢固的关系来为GN带来大量的外部资源，以对所有三个机构进行有意义的研究。我们将积极参加 GN指导委员会，并继续在我们的网站和GN研究设计中的其他站点以及手稿和赠款准备中指导更多的初级调查员。我们的主要目标之一是提高母亲和婴儿护理方面的设施表现。我们提出的通用方案施舍使用与设施护理相关的定义结果，例如，胎儿护理的胎儿和新生儿死亡率，例如，产后死亡人数和早期（前（前出院）新生儿死亡的总和）。使用简单的基于蜂窝电话的数据收集系统，对定义结果的快速反馈以及旨在减少与内部相关死亡的质量保证计划；我们希望能够在基于设施的怀孕结局上取得重大改善。