Advanced Technology QA Center

先进技术质量保证中心

• 批准号: 8690240
• 负责人: Jeff M Michalski
• 金额: $ 128.78万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-22 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8690240
• 关键词: Architecture; Archives; Bioinformatics; Biology; Brachytherapy; Caring; Clinical Trials; Clinical Trials Cooperative Group; Clinical trial protocol document; Collaborations; Computer software; Conformal Radiotherapy; Credentialing; Custom; Data; Data Collection; Databases; Development; Electronic Health Record; Environment; Evaluation; Evolution; Future; Goals; Image; Information Management; Institution; Instruction; Intensity-Modulated Radiotherapy; Link; Maintenance; Malignant Neoplasms; Medical Informatics; Medicine; Methods; Modality; Online Systems; Organ; Outcome; Physics; Procedures; Process; Protocols documentation; Radiation Oncology; Radiation Therapy Oncology Group; Radiation therapy; Radiosurgery; Research Infrastructure; Research Personnel; Resources; Risk; Services; System; Technology; Testing; Therapy Clinical Trials; Training and Education; Vision; base; design; digital; electronic data; image guided radiation therapy; image guided therapy; improved; meetings; multidisciplinary; multimodality; novel; open source; programs; quality assurance; tool; treatment planning; tumor

DESCRIPTION (provided by applicant): Advanced Technology QA Center Our plan is to capitalize on the infrastructure and strengths of the nation's existing quality assurance (QA) programs that comprise our Advanced Technology QA Consortium (ATC), including the Image-Guided Therapy Center (ITC), Radiation Therapy Oncology Group (RTOG), Radiological Physics Center (RPC), and the Quality Assurance Review Center (QARC) to maintain/develop an advanced medical informatics infrastructure that provides an environment in which institutions can submit, and QA Centers can receive, share, and analyze volumetric multimodality imaging/treatment planning/verification (ITPV) digital data. Specifically, we will (1) maintain/manage (and make incremental improvements as required to) the current electronic data submission of advanced technology (3DCRT, IMRT, SBRT, and brachytherapy) protocol credentialing and case data, archival storage, and remote QA review process utilizing ATC Method-1 (now referred to as the QuASAR-1 (Quality Assurance Submission, Analysis, and Review-1) system); (2) develop novel web-based remote-review tools that will enhance the efficient and effective review of protocols utilizing advanced technologies. The design infrastructure of these tools will assist the development of future protocol processes such as image-guided radiation therapy (IGRT) and adaptive radiation therapy (ART). The proposed system is referred to as QuASAR-2 and will be modular in design to promote efficient tools and subsystems development that achieve compatibility with existing software standards, including the Cancer Bioinformatics Grid (caBIG) and DICOM RT, and maintain/develop archival ITPV, credentialing/QA databases that can be linked with the cooperative group's clinical outcomes database; (3) assist cooperative groups in the development and management of advanced technology clinical trials protocols including (a) tumor/target volume and organ at risk definitions; (b) credentialing requirements and evaluation criteria; (c) electronic data submission requirements/instructions; (d) QA review procedures; and (4) serve as an educational resource to the nation's clinical trial cooperative groups and participating institutions for support of advanced technology radiation therapy clinical trials. Our ATC QA consortium approach will help avoid duplication of service/developmental efforts and promote development of uniform credentialing/QA criteria for clinical trials throughout all Cooperative Groups.

描述（由申请人提供）： 高级技术质量检查中心 我们的计划是利用国家现有质量保证（QA）计划的基础设施和优势，包括我们先进的技术QA联盟（ATC），包括图像引导治疗中心（ITC），放射治疗肿瘤学集团（RTOG）（RTOG）（RTOG）（RTOG）（RTOG），用于维护ASSINF/QUALITAT AN INDAT AN CERTAR AN CERTAR AN CERTAR AN CERTAR ANCIRES（QARC）（QARC）（QARC）（QARC）（QARC）（QARC）（QARC）机构可以提交的环境可以接收，共享和分析体积多模式成像/治疗计划/验证（ITPV）数字数据。具体而言，（1）将（1）维护/管理（并根据需要进行逐步改进）当前的电子数据提交（3DCRT，IMRT，SBRT和近距离治疗）协议证书和案例数据，档案存储和远程QA审查流程，利用ATC方法1（现在称为Quasar-1（Quasar-1）（Quasar-1）（质量Assurance consightance Syscrance cissiberance cissible，分析，分析，分析）; （2）开发新型的基于Web的远程浏览工具，以增强利用高级技术的协议的有效审查。这些工具的设计基础设施将有助于开发未来的协议过程，例如图像引导的放射疗法（IGRT）和自适应放射疗法（ART）。拟议的系统被称为Quasar-2，在设计中将是模块化的，以促进有效的工具和子系统开发，这些工具和子系统开发与现有软件标准相兼容，包括癌症生物信息信息电网（CABIG）和DICOM RT，并维护/开发/开发档案ITPV，资格/QA数据库，这些数据库可以与合作集团的Cliner Clinial Clinical的Clinial Clinical的Clinial Clinial Clinial Clinical的Clinicy Clinicals Casuse相连； （3）协助合作小组的发展和管理高级技术临床试验方案的开发和管理，包括（a）肿瘤/目标量和风险定义的器官； （b）凭证要求和评估标准； （c）电子数据提交要求/说明； （d）质量检查程序； （4）作为美国临床试验合作组织和参与机构的教育资源，以支持先进的技术放射治疗临床试验。我们的ATC QA联盟方法将有助于避免重复服务/发展工作，并促进在所有合作团体中为临床试验的统一证书/质量检查标准的发展。

项目成果

Accuracy and sources of error of out-of field dose calculations by a commercial treatment planning system for intensity-modulated radiation therapy treatments.

• DOI: 10.1120/jacmp.v14i2.4139
• 发表时间: 2013-03-04
• 期刊: Journal of applied clinical medical physics
• 影响因子: 2.1
• 作者: Huang JY;Followill DS;Wang XA;Kry SF
• 通讯作者: Kry SF

Variability in clinical target volume delineation for intensity modulated radiation therapy in 3 challenging cervix cancer scenarios.

在 3 种具有挑战性的宫颈癌场景中调强放射治疗的临床靶区描绘的可变性。

• DOI: 10.1016/j.prro.2015.06.011
• 发表时间: 2015
• 期刊: Practical radiation oncology
• 影响因子: 3.3
• 作者: Lim,Karen;Erickson,Beth;Jürgenliemk-Schulz,InaM;Gaffney,David;Creutzberg,CarienL;Viswanathan,Akila;Portelance,Lorraine;Beriwal,Sushil;Wolfson,Aaron;Bosch,Walter;DeLosSantos,Jennifer;Yashar,Catheryn;Jhingran,Anuja;Varia,Mahes
• 通讯作者: Varia,Mahes

Development of a modified head and neck quality assurance phantom for use in stereotactic radiosurgery trials.

• DOI: 10.1120/jacmp.v14i4.4313
• 发表时间: 2013-07-08
• 期刊: Journal of applied clinical medical physics
• 影响因子: 2.1
• 作者: Faught AM;Kry SF;Luo D;Molineu A;Bellezza D;Gerber RL;Davidson SE;Bosch W;Drzymala RE;Galvin J;Timmerman R;Sheehan J;Gillin MT;Ibbott GS;Followill DS
• 通讯作者: Followill DS

In Reply to O'Sullivan et al.

回复奥沙利文等人。

• DOI: 10.1016/j.ijrobp.2012.05.038
• 发表时间: 2012
• 期刊: International journal of radiation oncology, biology, physics
• 作者: Wang,Dian;Bosch,Walter;Roberge,David;Finkelstein,StevenE;Petersen,Ivy;Haddock,Michael;Chen,Yen-LinE;Delaney,ThomasF;Saito,NaoyukiG;Kirsch,DavidG;Hitchcock,YingJ;Wolfson,AaronH
• 通讯作者: Wolfson,AaronH

Dosimetric evaluation of heterogeneity corrections for RTOG 0236: stereotactic body radiotherapy of inoperable stage I-II non-small-cell lung cancer.

• DOI: 10.1016/j.ijrobp.2008.11.019
• 发表时间: 2009-03-15
• 期刊: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
• 影响因子: 7
• 作者: Xiao, Ying;Papiez, Lech;Paulus, Rebecca;Timmerman, Robert;Straube, William L.;Bosch, Wailter R.;Michalski, Jeff;Galvin, James M.
• 通讯作者: Galvin, James M.