Advances in Plasmodium Vivax Malaria Research

间日疟原虫疟疾研究进展

• 批准号: 8529293
• 负责人: JANE M CARLTON
• 金额: $ 0.6万
• 依托单位: NEW YORK ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-10 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8529293
• 关键词: Academia; Academy; Accounting; Address; Age; Asia; Asian Americans; Award; Awareness; Biology; Cessation of life; Child; Child Care; Clinical; Clinical Research; Clinical Trials; Collaborations; Communication; Communities; Congresses; Consensus; Country; Data; Development; Diagnosis; Disabled Persons; Disease; Doctor of Philosophy; Drug Industry; Drug resistance; Electronics; Ensure; Europe; Fellowship; Fostering; Foundations; Future; Generations; Genetic; Genomics; Goals; Government; Health Policy; In Vitro; Individual; Infection; International; Knowledge; Latin America; Life; Literature; Malaria; Mentors; Minority; Minority Groups; Mission; Molecular Biology; Molecular Genetics; Multimedia; Museums; National Institute of Child Health and Human Development; New York; Online Systems; Oral; Parasites; Participant; Plasmodium vivax; Prevention; Prevention Research; Prevention strategy; Printing; Process; Public Health; Publications; Reporting; Research; Research Personnel; Research Technics; Science; Severities; Spain; Technical Expertise; Technology; Translations; Travel; United States; Vivax Malaria; Woman; abstracting; career; data exchange; design; disability; drug discovery; economic impact; improved; in vivo; international center; lectures; meetings; neglect; novel; posters; prevent; public health relevance; symposium

DESCRIPTION (provided by applicant): Plasmodium vivax is the most widely distributed malaria parasite. There has been growing evidence that P. vivax is responsible for a significant proportion of global disease, and half of all malaria cases in Latin America and Asia. Despite recent recognition that the overall burden, economic impact, and severity of P. vivax disease have been underestimated, this species remains underrepresented in the scientific literature and fora. To address this unmet need, the New York Academy of Sciences, "la Caxia" Foundation, and International Center for Scientific Debate will jointly present a 2.5-day scientifi conference, Advances in Plasmodium Vivax Malaria Research, to be held at the CosmoCaixa science museum in Barcelona, Spain on June 5-7, 2013. The main objectives of the conference are to: (i) Provide a neutral forum for exchange of novel scientific knowledge and expertise among P. vivax investigators; (ii) Foster collaborations between complementary research groups and implementation teams, to enhance and leverage knowledge and technical expertise, and to prevent experimental redundancy; (iii) Showcase early career and underrepresented investigators (i.e. women, ethnic/racial minorities, and persons with disabilities) in P. vivax research via short talks, poster sessions, travel fellowships, and career mentoring; (iv) Disseminate the conference proceedings; and (v) Foster partnerships among academia, clinicians, government and regulatory agencies, to promote the global imperative of malaria control and eradication through the discussion and design of existing and future strategies. The conference is anticipated to attract approximately 150 international attendees from the United States and Europe, as well as Latin American and Asian countries in which P. vivax is endemic. Sessions will explore P. vivax molecular biology and genomics, host-parasite interactions, novel research techniques ('omics) to overcome barriers to in vitro, in vivo, and clinical study of P. vivax; drug resistance and drug discovery; and recent clinical trial and in-field efforts in P. vivx prevention, treatment, and control. Thematically, the conference goals align well with the NIAID's mission to find effective means by which to control and ultimately eliminate malaria. The majority of life-threatening P. vivax infections occur in children under the age of five years, consistent with the imperative of the NICHD to ensure the ability of children to live healthy, productive, disease-free lives. Lectures, interactive discussions, networking breaks, and a conference reception will provide a neutral forum for interaction of an international community who may not otherwise regularly interact at a single scientific meeting, ensuring that recent advances in P. vivax biology and public health strategies are disseminated among those at the forefront of vivax research. The dissemination of knowledge originating from the conference via an open-access, online multimedia report and additional print publication will ultimately foster advancement in the diagnosis, prevention, and treatment of this neglected parasite.

描述（由申请人提供）：间日疟原虫是分布最广泛的疟疾寄生虫。越来越多的证据表明，间日疟原虫造成了全球很大一部分疾病，以及拉丁美洲和亚洲所有疟疾病例的一半。尽管最近认识到间日疟原虫病的总体负担、经济影响和严重程度被低估，但该物种在科学文献和论坛中的代表性仍然不足。为了解决这一未满足的需求，纽约科学院、“la Caxia”基金会和国际科学辩论中心将在 CosmoCaixa 科学博物馆联合举办为期 2.5 天的科学会议“间日疟原虫疟疾研究进展” 2013 年 6 月 5 日至 7 日在西班牙巴塞罗那举行。会议的主要目标是： (i) 提供一个中立的论坛，以便 P.间日疫苗研究者； (ii) 促进互补研究小组和实施团队之间的合作，以增强和利用知识和技术专长，并防止实验重复； (iii) 通过简短演讲、海报会议、旅行奖学金和职业指导，展示间日疟原虫研究中早期职业和代表性不足的研究人员（即妇女、少数民族/种族和残疾人）； (iv) 传播会议记录； (v) 促进学术界、临床医生、政府和监管机构之间的伙伴关系，通过讨论和设计现有和未来战略，促进全球控制和消灭疟疾的必要性。此次会议预计将吸引约 150 名来自美国和欧洲以及间日疟原虫流行的拉丁美洲和亚洲国家的国际与会者。会议将探讨间日疟原虫分子生物学和基因组学、宿主-寄生虫相互作用、克服间日疟原虫体外、体内和临床研究障碍的新研究技术（“组学”）；耐药性和药物发现；以及最近在间日疟原虫预防、治疗和控制方面的临床试验和现场工作。从主题上看，会议目标与 NIAID 的使命高度契合，即寻找控制并最终消除疟疾的有效方法。大多数危及生命的间日疟原虫感染发生在五岁以下的儿童中，这符合 NICHD 确保儿童能够过上健康、富有成效、无疾病的生活的要求。讲座、互动讨论、交流休息和会议招待会将为国际社会的互动提供一个中立的论坛，否则他们可能不会在一次科学会议上定期互动，确保传播间日疟原虫生物学和公共卫生战略的最新进展是间日疫苗研究的前沿人士之一。通过开放获取的在线多媒体报告和其他印刷出版物传播会议产生的知识，最终将促进这种被忽视的寄生虫的诊断、预防和治疗方面的进步。