Group Phone-based Weight Control among Rural Breast Cancer Survivors
农村乳腺癌幸存者通过电话进行团体体重控制
基本信息
- 批准号:8478064
- 负责人:
- 金额:$ 53.34万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-08-01 至 2016-05-31
- 项目状态:已结题
- 来源:
- 关键词:AddressArthralgiaBehavioralBioavailableBiological MarkersBiomarker of Dietary IntakeBody Weight ChangesBody Weight decreasedC-reactive proteinCancer SurvivorCancer SurvivorshipCessation of lifeChargeChronicCounselingCountyDeteriorationDiagnosisDietEducationEmotionalEstradiolFastingFatigueFutureHigh PrevalenceHigh Risk WomanIndividualInsulinInterventionLeptinLifeLife StyleLong-Term CareLymphedemaMailsMaintenanceMalignant NeoplasmsMenopausal SymptomMethodsObesityOutcomeOverweightParticipantPersonal SatisfactionPhasePhysical activityPrivacyProviderPsyche structureQuality of lifeRandomized Controlled TrialsRecurrenceReportingResearchRiskRuralSecond Primary CancersServicesSocial supportSurvivorsSymptomsTelephoneTestosteroneTimeUninsured Medical ExpenseWeightWeight GainWeight maintenance regimenWomanWorkadiponectinbasebreast cancer diagnosiscancer recurrencecancer riskcancer therapycostcost effectivecost effectivenesscost efficientdepressive symptomsgroup supporthealth disparityimprovedinnovationmalignant breast neoplasmmetropolitanmortalitymulti-site trialnovelprogramsrural areasecondary outcomesocialsymposiumtreatment effect
项目摘要
DESCRIPTION (provided by applicant): Women who are obese at breast cancer diagnosis have a 1.5 to 2.5 increased risk of recurrence and death compared to their normal weight counterparts. Moreover, weight gain and decreased physical activity are common after diagnosis and also increase the likelihood of breast cancer recurrence and death. Rural women suffer from health disparities in breast cancer diagnosis and treatment. Women of the most rural counties also have the highest prevalence of obesity compared to urban women. To address these disparities, the overarching objective of this application is to develop a clinically effective and cost efficient strategy for delivering a weight control intervention to rural breast cancer survivors. Group phone-based treatment via conference call is a novel treatment delivery approach that we have shown to be effective for initial weight loss among rural breast cancer survivors and more effective than the standard individual phone-based approach among rural women. This innovative method of providing group treatment addresses access barriers in rural areas and may be especially ideal for rural breast cancer survivors because it provides social support in conjunction with a level of anonymity. Rural breast cancer survivors are more likely to be isolated, to have heightened concerns about privacy, and to report difficulty adjusting to breast cancer. At the same time, they have less access to professional support services, and thus are more likely to have unmet support needs surrounding both cancer and weight management. The opportunity to engage in lifestyle change with other survivors by phone may provide social support in a confidential setting at the same time it enhances diet, physical activity, and weight, as well as quality of life. However, the impact of group phone counseling during extended care for weight loss maintenance beyond six months remains unknown. Weight loss maintenance is the more challenging phase of treatment when weight regain is common, and this regain presents a potential risk for breast cancer recurrence. This randomized controlled trial will evaluate the effects of group phone-based treatment for weight loss maintenance among rural breast cancer survivors, compared to an established mail- based education comparison condition, subsequent to a six month group phone-based weight loss phase for both conditions. In addition to the intervention impact on weight loss maintenance, the study will provide estimates of incremental cost-effectiveness per kg loss between the two conditions and the impact on secondary outcomes including quality of life, breast cancer risk biomarkers, dietary intake, and physical activity. We aim to produce long-term weight loss maintenance, associated biomarker modulation, and improved quality of life in a cost-effective way that can be extended to hard-to-reach rural survivors.
描述(由申请人提供):与正常体重对应物相比,在乳腺癌诊断时肥胖的妇女的复发风险和死亡风险增加了1.5至2.5。此外,诊断后体重增加和体育活动减少是常见的,也增加了乳腺癌复发和死亡的可能性。农村妇女在乳腺癌诊断和治疗中患有健康差异。与城市妇女相比,大多数农村县的妇女的肥胖症患病率也最高。为了解决这些差异,本应用的总体目标是制定一种临床有效且具有成本效益的策略,以对农村乳腺癌幸存者进行体重控制干预。通过电话会议进行基于电话的治疗是一种新型的治疗方法,我们证明它对农村乳腺癌幸存者的初始体重减轻有效,并且比农村妇女的标准基于电话的方法更有效。这种提供小组治疗的创新方法解决了农村地区的访问障碍,对于农村乳腺癌幸存者来说尤其是理想的选择,因为它与一定程度的匿名性提供了社会支持。农村乳腺癌幸存者更有可能被隔离,对隐私的担忧加剧,并报告难以适应乳腺癌。同时,他们获得了专业支持服务的访问权,因此更有可能在癌症和体重管理方面具有未满足的支持需求。通过电话与其他幸存者进行生活方式改变的机会,可以在机密环境中提供社会支持,同时它可以增强饮食,体育锻炼和体重以及生活质量。但是,在扩展护理期间,小组电话咨询对减肥维持六个月的影响仍然未知。当体重恢复很普遍时,减肥维持是更具挑战性的治疗阶段,并且这种恢复会带来乳腺癌复发的潜在风险。这项随机对照试验将与建立的基于邮寄的教育比较状况相比,将基于小组电话治疗对农村乳腺癌幸存者的减肥维持的影响,这是两种情况下的六个月基于组的基于电话的减肥阶段。除了对减肥维持的影响外,这项研究还将估计两种情况之间每公斤损失的成本效益以及对次要结果的影响,包括生活质量,乳腺癌风险生物标志物,饮食摄入量和体育活动。我们旨在以具有成本效益的方式生产长期减肥,相关的生物标志物调制以及改善生活质量,可以扩展到难以到达的农村幸存者。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Christie Befort其他文献
Christie Befort的其他文献
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{{ truncateString('Christie Befort', 18)}}的其他基金
Rural Engagement in TelemedTeam for Options in Obesity Treatment Solutions (RE-TOOL)
农村参与远程医疗团队寻求肥胖治疗解决方案选择 (RE-TOOL)
- 批准号:
10372530 - 财政年份:2022
- 资助金额:
$ 53.34万 - 项目类别:
Rural Engagement in TelemedTeam for Options in Obesity Treatment Solutions (RE-TOOL)
农村参与远程医疗团队寻求肥胖治疗解决方案选择 (RE-TOOL)
- 批准号:
10573294 - 财政年份:2022
- 资助金额:
$ 53.34万 - 项目类别:
Group Phone-based Weight Control among Rural Breast Cancer Survivors
农村乳腺癌幸存者通过电话进行团体体重控制
- 批准号:
8676721 - 财政年份:2011
- 资助金额:
$ 53.34万 - 项目类别:
Group Phone-based Weight Control among Rural Breast Cancer Survivors
农村乳腺癌幸存者通过电话进行团体体重控制
- 批准号:
8274657 - 财政年份:2011
- 资助金额:
$ 53.34万 - 项目类别:
Group Phone-based Weight Control among Rural Breast Cancer Survivors
农村乳腺癌幸存者通过电话进行团体体重控制
- 批准号:
8185106 - 财政年份:2011
- 资助金额:
$ 53.34万 - 项目类别:
Biological Signals of Weight Loss in African-American Women
非裔美国女性减肥的生物信号
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8143075 - 财政年份:2010
- 资助金额:
$ 53.34万 - 项目类别:
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