A QUANTITATIVE COMPARISON OF NIRS AND FMRI ACROSS MULTIPLE COGNITIVE TASKS

跨多个认知任务的 NIRS 和 FMRI 的定量比较

• 批准号: 8362914
• 负责人: Xu Cui
• 金额: $ 1.3万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362914
• 关键词: Adult; Age; Annual Reports; Back; Brain; Cognitive; Disadvantaged; Fingers; Functional Magnetic Resonance Imaging; Funding; Grant; Hemoglobin; Inferior; Judgment; Left; Magnetic Resonance; Magnetic Resonance Imaging; Measures; National Center for Research Resources; Near-Infrared Spectroscopy; Noise; Principal Investigator; Reading; Relative (related person); Research; Research Infrastructure; Resolution; Resources; Short-Term Memory; Signal Transduction; Source; Stimulus; Structure; Technology; United States National Institutes of Health; Visit; Visuospatial; abstracting; cost; male

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. INTRODUCTION: Near-infrared spectroscopy (NIRS) is an increasingly popular technology for studying brain function. NIRS offers several advantages relative to functional magnetic resonance imaging (fMRI), including the ability to measure concentration changes of both oxygenated and deoxygenated hemoglobin, finer temporal resolution, and ease of administration, as well as disadvantages, most prominently inferior spatial resolution, inability to directly measure signals from deep-brain structures, and decreased signal-to-noise ratio (SNR). In this study, we compared NIRS and fMRI signals to assess spatial and temporal similarities. METHODS: Thirteen healthy adults (mean age 27.9, age range 21-42, 6 males) underwent simultaneous NIRS and fMRI scanning while they completed four experimental paradigms: left finger tapping (tap), go/no-go (nog), judgment of line orientation (jlo), and an N-back working memory task using visuospatial stimuli (vis). We performed detailed comparisons of the signals in both temporal and spatial domains. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的首席研究员可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 简介：近红外光谱 (NIRS) 是一种日益流行的研究大脑功能的技术。近红外光谱仪 与功能磁共振成像 (fMRI) 相比，具有多种优势，包括能够测量 含氧血红蛋白和脱氧血红蛋白的浓度变化、更精细的时间分辨率以及易于 管理以及缺点，最突出的是空间分辨率较差，无法直接测量信号 来自深部大脑结构，并降低了信噪比（SNR）。在本研究中，我们比较了 NIRS 和 fMRI 信号 评估空间和时间相似性。 方法：13 名健康成年人（平均年龄 27.9 岁，年龄范围 21-42，6 名男性）同时接受 NIRS 和 fMRI 扫描时他们完成了四个实验范式：左手指敲击（tap）、走/不走（nog）、线条判断 定向（jlo）和使用视觉空间刺激（vis）的 N 回工作记忆任务。我们进行了详细的比较 时域和空间域中的信号。 要了解卢卡斯中心正在进行的其他项目，请访问 http://rsl.stanford.edu/（卢卡斯年度报告和 ISMRM 2011 摘要）