Comparative effects of resistance training protocols in older adults at risk of m

阻力训练方案对有 m 风险的老年人的比较效果

• 批准号: 8366661
• 负责人: Summer B. Cook
• 金额: $ 36.02万
• 依托单位: UNIVERSITY OF NEW HAMPSHIRE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8366661
• 关键词: Activities of Daily Living; Acute; Adult; Affect; Age-Years; Area; Arthritis; Attenuated; Blood flow; Chronic; Comorbidity; Control Groups; Coupled; Elderly; Equilibrium; Exercise; Exertion; Female; Flexor; Hypertrophy; Individual; Intervention; Interview; Japan; Joints; Knee; Leg; Light; Measures; Muscle Weakness; Pain; Participant; Perception; Performance; Physical Function; Physiological; Protocols documentation; Quality of life; Recommendation; Regimen; Reporting; Research Personnel; Resistance; Risk; Self Efficacy; Structure; Surveys; Testing; Training; Training Programs; United States; Walking; World Health Organization; age related; aging population; base; combat; comparative; design; disability; experience; fitness; improved; innovation; male; muscle form; muscle strength; pressure; research study; response; satisfaction; strength training; young adult

DESCRIPTION (provided by applicant): Maintaining and improving muscle strength can positively affect an older adult's ability to perform activities of daily living and in turn could esult in greater physical independence and quality of life. Currently it is recommended that older adults perform bouts of high-load (HL) resistance exercise at 60-80% of their maximum strength. However, HL training may not be feasible or safe for individuals who are very weak, frail, arthritic, or in a diseased state. The overall purpose of this study is to directly compare he training adaptations and perceptions of an innovative resistance training program to the currently recommended HL training regimen in older adults. Resistance training at very light loads and volumes (~20-30% of maximum strength) coupled with a blood flow restriction (LLBFR) has resulted in increased muscle mass and strength in young and old individuals, and these improvements are of similar magnitude to that seen with traditional HL resistance exercise. This type of resistance exercise is regularly performed in Japan, where it is referred to as KAATSU (meaning literally: strength training "with the addition of pressure"). Yet KAATSU (henceforth referred to as LLBFR resistance exercise) remains an unfamiliar concept in the United States. There are a limited number of studies that have investigated the use of LLBFR training to increase muscle strength in the aging population, but it is unknown whether this exercise regimen has any impact on functional capacity or quality of life. Therefore, the specific purposes of this study are to determine 1) if LLBFR resistance training is as tolerable and feasible as HL resistance training in older adults; and 2) whether similar adaptations in muscle strength, functional capacity and quality of life in older adults are evident after HL resistance training and LLBFR resistance training. To answer these questions, 45 males and females over 65 years of age who are classified as "at risk of developing mobility limitations" will be studied. The subjects will be placed randomly into one of 3 groups: HL resistance training, LLBFR resistance training, and a control group. Subjects will undergo muscle strength testing, tests of physical functioning and qualitative interviews before, midway and after 12 weeks of resistance training on the upper legs. Establishing the efficacy and tolerance of LLBFR training programs in older adults at risk of mobility limitations would lay the groundwork for implementation of LLBFR resistance exercise in older and weaker adults that cannot engage in HL resistance training. Muscle weakness and subsequent disability and decreased quality of life could be attenuated in older adults if LLBFR exercise is shown to be an effective alternative to HL resistance training. PUBLIC HEALTH RELEVANCE: While high-load resistance training is often prescribed to combat muscle weakness by increasing muscle strength and size, this type of exercise may not be appropriate for all older adults, particularly those with joint discomfort. Resistance training t a low-load coupled with a moderate blood flow restriction may be a practical alternative. The proposed study aims to determine if these two training regimens have similar effects on older adults' muscle strength and size, their ability to perform everyday tasks (functional capacity), and their quality of life.

描述（由申请人提供）：维持和改善肌肉力量会对老年人进行日常生活活动的能力产生积极影响，进而可以使身体独立和生活质量更大。目前，建议老年人以最大强度的60-80％进行高负载（HL）抵抗运动。但是，对于非常虚弱，脆弱，关节炎或患病状态的人来说，HL培训可能不可行或安全。这项研究的总体目的是直接将他对创新抵抗培训计划的培训适应和看法与当前建议的HL培训方案进行比较。与血流限制（LLBFR）相连的非常轻的载荷和体积（〜20-30％的最大强度）的阻力训练已导致年轻人和老年人的肌肉质量和力量增加，并且这些改善的幅度与传统的HL耐药性运动相似。这种类型的抵抗运动定期在日本进行 如Kaatsu（从字面意思是：力量训练“加压力”）。然而，在美国，Kaatsu（此后称为LLBFR抵抗运动）仍然是一个陌生的概念。有限数量的研究研究了使用LLBFR训练来增加人口老龄化的肌肉力量，但是尚不清楚该运动方案是否对功能能力或生活质量有任何影响。因此，本研究的具体目的是确定1）LLBFR耐药训练是否与老年人的HL耐药性训练一样可耐受和可行； 2）在HL抵抗训练和LLBFR耐药训练后，老年人的肌肉力量，功能能力和生活质量是否相似。为了回答这些问题，将研究45岁以上65岁以上的男性和女性，他们将被列为“有可能发展出流动性限制的风险”。 这些受试者将被随机分为3组之一：HL耐药性训练，LLBFR耐药训练和对照组。受试者将接受肌肉力量测试，进行身体功能的测试以及在上腿进行12周的抵抗训练之前，进行定性访谈。建立LLBFR培训计划在具有行动能力限制风险的老年人中的疗效和容忍度将为实施LLBFR耐药性运动的基础奠定了基础，而较老的和较弱的成年人无法进行HL抵抗训练。如果LLBFR运动被证明是进行HL耐药性训练的有效替代方法，则老年人的肌肉无力和随后的残疾和降低生活质量可能会减弱。 公共卫生相关性：虽然通常会开出高负载抵抗训练来通过增加肌肉力量和大小来打击肌肉无力，但这种类型的运动可能并不适合所有老年人，尤其是那些患有联合不适的老年人。耐药性训练t低负载加上适中的血流限制可能是实际的选择。拟议的研究旨在确定这两种训练方案是否对老年人的肌肉力量和大小，执行日常任务（功能能力）的能力以及其生活质量的能力是否具有相似的影响。

项目成果

Knee extensor power asymmetry is unrelated to functional mobility of older adults.

• DOI: 10.1016/j.exger.2017.08.008
• 发表时间: 2017-11
• 期刊: Experimental gerontology
• 影响因子: 3.9
• 作者: LaRoche DP;Villa MR;Bond CW;Cook SB
• 通讯作者: Cook SB