University of New Mexico Health Sciences Center Animal Resource Facility Improvem

新墨西哥大学健康科学中心动物资源设施改善

• 批准号: 8183595
• 负责人: Kevin C O'Hair
• 金额: $ 49.99万
• 依托单位: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8183595
• 关键词: Accreditation; Air; Award; Behavioral; Biomedical Research; Brain; Breeding; Cardiovascular Diseases; Center for Translational Science Activities; Child health care; Clinical; Clinical Sciences; Communicable Diseases; Community Health Centers; Core Facility; Development; Environmental Health; Equipment; Failure; Floor; Frequencies; Genetic; Goals; Health Sciences; Housing; Image; Immunity; Maintenance; Malignant Neoplasms; Mechanics; Medical; Metabolic Diseases; Mus; New Mexico; Plumbing; Resources; Science; Services; Technology; Temperature; Time; United States National Institutes of Health; Universities; Water; animal care; animal facility; animal resource; cost; exhaust; improved; meetings; programs; research facility

DESCRIPTION (provided by applicant): The aim of this G20 application is to request $499,885.80 to support purchase of a new tunnel washer, 13 ventilated mouse racks and associated renovation of 2,197 gsf / 2,197 nsf to support installation of this equipment at the University of New Mexico (UNM) Health Sciences Center (HSC) Animal Resource Facility (ARF). This project is located in contiguous space within the Biomedical Research Facility (BRF) and the Basic Medical Sciences Building (BMSB). The BRF/BMSB animal facilities comprise the major component of ARF but the core also includes housing in two HSC satellite imaging facilities. This project builds upon improvements from two previous renovations completed in the BRF and BMSB ARF in 2002 and 2008, respectively. Those renovations upgraded mechanical (HVAC with DDC controls and environmental alarms), floors, finishes and roofing. Although past projects modernized the ARF, we have additional needs: To replace a failing tunnel washer which supports all cage washing for HSC and continue to transition from static microisolator mouse cages to ventilated cages. This project is critical for us to continue meeting our ongoing strategic and programmatic goals which are to: Expand a productive partnership between the NIH and UNM HSC; enhance our support to the HSC Signature Programs (Brain and Behavioral Illnesses, Cancer, Cardiovascular and Metabolic Disease, Child Health, Environmental Health, and Infectious Diseases and Immunity); expand development of new emerging synergies with ARF as one of the technology cores in our newly awarded Clinical and Translational Science Center (CTSC); improve animal care compliance; and sustain AAALAC accreditation which HSC have continued since 1973. This proposal includes renovation (connection to existing plumbing/electrical service and adjacent finishes) to install/replace a 26 year old tunnel washer in BMSB room G10 (1608 gsf/nsf) and to extend exhaust ports from room exhaust and add electrical outlets that will support use of the 13 ventilated mouse racks to be located in BRF G82E and G82F (589 gsf / 589 nsf), which are the primary breeding rooms located in our genetic mouse breeding barrier. The exiting tunnel washer does not sustain required temperatures, leaks water, has a non-functional dryer and requires extensive maintenance making the unit nonfunctional at critical times. New equipment under this project will improve animal care and enhance UNM'S sustainability goals by saving energy and water and improving indoor (cage/room) air quality - specifically due to higher efficiency of the new washer with fewer failures and no water leaks and fresh air to mouse cages is exhausted from the building which improves air quality and enables reduced cage change frequency with less washing, fewer resources, reduced labor and lower costs to core users. This project is critical if we are to excel the pace of discoveries through our interdisciplinary CTSC with a primary goal to continue to promote a healthier public.

描述（由申请人提供）：该G20申请的目的是要求$ 499,885.80，以支持购买新的隧道洗衣机，13个通风的鼠标架以及2,197 GSF / 2,197 NSF的相关装修，以支持新墨西哥大学（UNM）健康科学中心（HSC）动物资源（HSC）动物资源（HSC）动物资源（HSC）动物资源（ARF）在此设备上安装此设备。该项目位于生物医学研究机构（BRF）和基本医学大楼（BMSB）内的连续空间中。 BRF/BMSB动物设施是ARF的主要组成部分，但核心还包括两个HSC卫星成像设施中的外壳。该项目的基础是分别在2002年和2008年在BRF和BMSB ARF完成的两次翻新基础上进行了改进。这些翻新升级的机械（带有DDC控件和环境警报的HVAC），地板，饰面和屋顶。尽管过去的项目现代化了ARF，但我们还有其他需求：替换失败的隧道洗衣机，该隧道洗衣机支持HSC的所有笼子洗涤物，并继续从静态微型弹药鼠标笼子过渡到通风的笼子。对于我们来说，继续实现我们正在进行的战略和程序化目标至关重要的是：扩大NIH和UNM HSC之间的富有成效的伙伴关系；增强我们对HSC签名计划的支持（大脑和行为疾病，癌症，心血管和代谢疾病，儿童健康，环境健康以及传染病和免疫力）；扩大与ARF新兴协同作用的开发，是我们新授予的临床和转化科学中心（CTSC）的技术核心之一；改善动物护理依从性；并维持HSC自1973年以来一直持续的AAAALAC认证。该提议包括翻新（与现有的管道/电气服务和相邻饰面的连接），以安装/更换26岁的隧道垫圈在BMSB室G10（1608 GSF/NSF）（1608 GSF/NSF）（1608 GSF/NSF）（1608 GSF/NSF）（1608 GSF/NSF），并延长了室内排气端口和添加型号的架子，并将其添加到8号电气库中，并将其置于13通道的鼠标，以供应鼠标的速度，以置于13通道的鼠标。 （589 GSF / 589 NSF），它是位于我们遗传小鼠繁殖屏障的主要繁殖室。退出的隧道洗衣机不维持所需的温度，泄漏水，具有非功能干燥机，需要大量维护，使该单元在关键时期非功能。该项目下的新设备将通过节省能源和水来改善UNM的可持续性目标，并改善室内（CAGE/ROOM）空气质量 - 特别是由于新垫圈的效率更高，较少的故障效率较少，没有漏水和新鲜的空气到鼠标上耗尽了建筑物，从而可以改善空气质量，从而减少CAGE的频率，从而减少了较少的洗涤频率，从而减少了减少劳动力的劳动力，从而减少了劳动力和少量的劳动，从而减少了劳动力和劳动力，从而降低了劳动力和劳动力，从而可以减少劳动力，从而降低了劳动力和少量的劳动，从而可以减少型号。如果我们要通过我们的跨学科CTSC以继续促进更健康的公众的主要目标，这将是至关重要的。