Renal Disease Epidemiology Training Grant

肾病流行病学培训补助金

• 批准号: 8300050
• 负责人: LAWRENCE JOHN APPEL
• 金额: $ 31.51万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-20 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8300050
• 关键词: Epidemiology; Grant; Kidney Diseases; Training

DESCRIPTION (provided by applicant): The incidence and prevalence of treated end-stage renal disease (ESRD) has increased relentlessly in the U.S. since initiation of the Medicare ESRD Program in 1973. Many more Americans have less severe forms of chronic kidney disease. Thus there is a national need to train more scientists to study this societal health problem. Renal disease epidemiology offers the potential to help reduce the morbidity, mortality and societal costs associated with kidney disease and is a natural complement to the substantial strengths in basic science research in renal disease. This proposal is a competitive renewal application, years 16 to 20, for a NRSA to fund a Renal Disease Epidemiology Training Program at The Johns Hopkins Medical Institutions. The Program is based in the Welch Center for Prevention, Epidemiology, and Clinical Research and the Department of Epidemiology; it takes advantage of the faculty's strengths in the application of epidemiologic methods to important issues in renal disease and their ability to bridge the disciplines of basic science and epidemiology. A program Director (Dr. Klag), co-director (Dr. Appel), and 10 other nationally recognized renal disease epidemiologists serve as faculty advisers; 3 other faculty with experience in renal disease epidemiology are also available for mentorship. An Advisory Committee of institutional leaders and internationally recognized researchers advise the directors and monitor progress. We have demonstrated our ability to recruit high quality candidates and rigorously train them in clinical and epidemiologic renal research methods. Over the last 10 years, a total of 18 trainees have been supported, 5 of whom are still in training. Of the remaining 13, 12 are pursuing academic careers. These trainees have published 155 papers. This funding has revitalized the Pediatric Nephrology fellowship at our institution, forged close collaborative relations between the participating units, and produced a cadre of successful young investigators who are doing innovative research at Johns Hopkins and other institutions across the US.. PUBLIC HEALTH RELEVANCE: This program provides rigorous training in statistics, epidemiology, and clinical research methods to future leaders who will find new ways to prevent and treat kidney disease. The faculty and trainees form collaborations and use state-of-the art methods to characterize risk factors, including genes, for kidney disease as well as to design and carry out clinical trials. This program has profoundly influenced the curriculum and research agenda of the Johns Hopkins Medical Institutions.

描述（由申请人提供）：自1973年启动Medicare ESRD计划以来，在美国，治疗的终末期肾脏疾病（ESRD）的发病率和患病率不断增加。更多的美国人的慢性肾脏疾病形式较少。因此，国家需要培训更多的科学家来研究这个社会健康问题。肾脏疾病流行病学提供了帮助降低与肾脏疾病相关的发病率，死亡率和社会成本的潜力，并且自然地补充了肾脏疾病基础科学研究的实质优势。 该提案是16至20年的竞争性更新申请，供NRSA资助约翰·霍普金斯医疗机构的肾脏疾病流行病学培训计划。该计划设在韦尔奇预防，流行病学和临床研究中心以及流行病学系；它利用教师在将流行病学方法应用于肾脏疾病的重要问题及其桥接基础科学和流行病学学科的能力方面的优势。计划主任（KLAG博士），联合导演（Appel博士）和其他10位全国认可的肾脏疾病流行病学家担任教职顾问； 3其他具有肾脏疾病流行病学经验的教师也可以供指导。机构领导人和国际认可的研究人员的咨询委员会建议董事并监督进度。 我们已经证明了我们招募高质量候选者并严格培训他们的能力，以临床和流行病学的肾脏研究方法进行培训。在过去的十年中，总共支持18名学员，其中5名仍在接受培训。在其余的13个中，有12个正在从事学术职业。这些学员发表了155篇论文。这项资金使我们机构的小儿肾脏病奖学金振兴了参与单位之间的密切合作关系，并培养了一群成功的年轻调查员，他们正在约翰·霍普金斯（Johns Hopkins）和美国其他机构进行创新研究。 公共卫生相关性：该计划在统计，流行病学和临床研究方法方面提供了严格的培训，以寻找可以预防和治疗肾脏疾病的新方法的未来领导者。教师和学员组建了合作，并使用最先进的方法来表征肾脏疾病在内的风险因素，以及设计和进行临床试验。该计划深远影响了约翰·霍普金斯医疗机构的课程和研究议程。