Electrophysiological/ Computational Core

电生理/计算核心

基本信息

批准号：
7980645
负责人：
Jose Luis Contreras-Vidal
金额：
$ 34.54万
依托单位：
UNIV OF MARYLAND, COLLEGE PARK
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-10 至 2015-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7980645
关键词：
Adult Animal Housing Animals Attention Behavioral Brain Callithrix jacchus jacchus Capuchin Monkey Child Child Development Collection Computer Interface Computer software Computers Cornea Custom Data Data Analyses Data Collection Data Storage and Retrieval Devices Electrodes Electroencephalography Electronics Electrophysiology (science)Equipment Ethology Eye Foxes Funding Glass Grant Head Housing Human Human Development Imagery Individual Infant Israel Kinesiology Laboratories Location Macaca mulatta Maps Maryland Methods Microelectrodes Modeling Monitor Monkeys Motion Motor Movement National Institute of Child Health and Human Development Neonatal Neurons Neurosciences Neurosciences Research Nurseries Performance Postdoctoral Fellow Process Public Health Schools Research Research Project Grants Running Saimiri Services Site Source Specialist Staging Students System Testing Time United States National Institutes of Health Universities Wing Work analog base comparative design digital experience foot graduate student independent component analysis meetings mirror neuron system neurophysiology nonhuman primate programs research facility research study response social group sound square foot

项目摘要

Objectives Core B, the electrophysiology and computational core, will develop standard methods for processing and analysis of EEG data from both human and non-human primate studies that can be used to identify mirror neuron system (MNS) activity. Both standard nonparametric spectral estimation methods and more recent methods based on parametric modeling, wavelet analysis, and independent component analysis of brain activity will be used to identify mu like responses in infants, children and adults and in the non-human primate studies. Moreover, cortical source analysis will also provide a window to the generators of the mu activity as described below. This core will provide foundational support to each of the Projects for collecfing electrophysiological data examining the mirror system during observafion and performance of action in human infants (Projects I and II), human children (Project I and IV) and human adults (Projects I and IV) as well as non-human primate infants (Projects I and III) and non-human primate adults (Project III).

目标核心 B，即电生理学和计算核心，将开发处理和计算的标准方法。分析来自人类和非人类灵长类动物研究的脑电图数据，可用于识别镜像神经元系统（MNS）活动。标准非参数谱估计方法和更新的方法基于大脑参数建模、小波分析和独立成分分析的方法活动将用于识别婴儿、儿童、成人以及非人类灵长类动物的 mu 样反应研究。此外，皮层源分析还将为 mu 活动的生成器提供一个窗口：如下所述。该核心将为每个收集项目提供基础支持在观察和执行人类动作时检查镜像系统的电生理数据婴儿（项目 I 和 II）、人类儿童（项目 I 和 IV）和人类成人（项目 I 和 IV）以及非人类灵长类婴儿（项目 I 和 III）和非人类灵长类成年动物（项目 III）。