An innovative tool for assessment of gait dysfunction in the clinical setting

用于评估临床环境中步态功能障碍的创新工具

• 批准号: 8058282
• 负责人: Brian Stewart Randall Armstrong
• 金额: $ 21.54万
• 依托单位: METRIA INNOVATION, INC.
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8058282
• 关键词: 3-Dimensional; Activities of Daily Living; Affect; Agreement; Businesses; Cardiopulmonary; Clinic; Clinical; Communities; Computer software; Data; Data Collection; Data Reporting; Dependence; Development; Diagnostic; Disease; Environment; Evaluation; Functional disorder; Funding; Gait; Goals; Health Professional; Healthcare; Human; Impairment; Intervention; Laboratory Research; Lead; Lighting; Measurement; Methods; Moire Patterns; Motion; Movement; Neurologic; Observational Study; Optics; Orthopedics; Outcome; Patients; Persons; Phase; Physical therapy; Population; Positioning Attribute; Protocols documentation; Rehabilitation therapy; Resolution; Role; Site; Small Business Innovation Research Grant; Staging; System; Technical Expertise; Technology; Testing; Time; Validity and Reliability; Video Recording; Walking; base; clinical efficacy; clinical research site; commercialization; cost; cost effective; disability; gait examination; improved; innovation; instrument; kinematics; meetings; mortality; neuromuscular; novel; operation; portability; tool; treatment planning; two-dimensional

DESCRIPTION (provided by applicant): The overall goal of this SBIR Phase I proposal is to establish the measurement reliability and the clinical feasibility of the RGR-GAIT instrumented gait analysis system. Gait dysfunction can dramatically affect a person's ability to perform activities of daily living, and assessment of gait is a critical component of physical therapy practice. Currently, instrumented gait analysis is inaccessible to the vast majority of physical therapy clinics. Because of this, most clinicians depend on observational gait analysis, which has been shown to have inadequate reliability and validity. Further, two-dimensional gait analysis does not capture many critical three- dimensional (3-D) gait features. Clinical outcomes could be improved if three-dimensional gait deviations could be more objectively quantified in a typical clinic, but current 3-D systems are too space intensive, costly, and technically demanding. The Retro-Grate Reflector (RGR) 3-D motion capture system is a novel single-camera 3-D motion tracking technology that fills the gap between clinical need and currently available 3-D systems. Through innovation in the use of moire patterns generated by a lightweight, multi-layer passive optical target, the RGR technology is able to determine 3-D information with a single camera. The RGR system's single camera operation, automatic tracking of multiple targets and robustness to lighting conditions make it less technically demanding and overcomes the barriers for broad clinical use of instrumented gait analysis. Metria Innovation is developing the RGR-GAIT system for clinical deployment. The two aims of this proposal are to establish the inter-trial, inter-session, and inter-tester repeatability and to demonstrate the clinical feasibility of the RGR-GAIT system. A system will be constructed and deployed to a physical therapy clinic where the testing will take place. For the first aim, two therapists will collect 3-D gait data on ten healthy subjects across two days. In addition, ten orthopedic patients will be assessed by two therapists on a single day. These reliability data will inform aim 2, which will objectively quantify gait deviations in the ten orthopedic patients. The results of this study will lead to Phase II, which will focus on establishing measurement reliability between clinical sites and within clinical populations. Phase II will also refine the technology, software, and technical support for full commercialization. PUBLIC HEALTH RELEVANCE: Assessment of walking is a critical component of rehabilitation for a variety of orthopedic, neurological, and cardiopulmonary conditions. Improved assessment of walking and other movement in the clinical setting can dramatically improve patient outcomes and reduce costs by improving treatment planning. The result of this project will be an innovative gait analysis system to meet this need.

描述（由申请人提供）：该 SBIR 第一阶段提案的总体目标是建立 RGR-GAIT 仪表化步态分析系统的测量可靠性和临床可行性。步态功能障碍会极大地影响一个人进行日常生活活动的能力，步态评估是物理治疗实践的重要组成部分。目前，绝大多数物理治疗诊所无法进行仪器化步态分析。因此，大多数临床医生依赖观察性步态分析，但事实证明这种分析的可靠性和有效性不足。此外，二维步态分析无法捕获许多关键的三维 (3-D) 步态特征。如果能够在典型诊所中更客观地量化三维步态偏差，则可以改善临床结果，但当前的 3D 系统空间过于密集、成本高昂且技术要求较高。 Retro-Grate Reflector (RGR) 3-D 运动捕捉系统是一种新颖的单摄像头 3-D 运动跟踪技术，填补了临床需求与当前可用 3-D 系统之间的空白。通过对轻质多层无源光学目标生成的莫尔图案的使用进行创新，RGR 技术能够使用单个摄像头确定 3D 信息。 RGR 系统的单摄像头操作、多个目标的自动跟踪以及对照明条件的鲁棒性使其技术要求较低，并克服了仪器化步态分析广泛临床应用的障碍。 Metria Innovation 正在开发用于临床部署的 RGR-GAIT 系统。该提案的两个目的是建立试验间、会话间和测试者间的可重复性，并证明 RGR-GAIT 系统的临床可行性。将构建一个系统并将其部署到将进行测试的物理治疗诊所。对于第一个目标，两名治疗师将在两天内收集 10 名健康受试者的 3D 步态数据。此外，两名治疗师将在一天内对十名骨科患者进行评估。这些可靠性数据将为目标 2 提供信息，目标 2 将客观地量化 10 名骨科患者的步态偏差。这项研究的结果将进入第二阶段，重点是建立临床地点之间和临床人群内的测量可靠性。第二阶段还将完善技术、软件和技术支持，以实现全面商业化。 公共卫生相关性：步行评估是各种骨科、神经和心肺疾病康复的重要组成部分。改进临床环境中步行和其他运动的评估可以通过改进治疗计划来显着改善患者的治疗效果并降低成本。该项目的成果将是一个创新的步态分析系统来满足这一需求。