An innovative tool for assessment of gait dysfunction in the clinical setting

用于评估临床环境中步态功能障碍的创新工具

• 批准号: 8058282
• 负责人: Brian Stewart Randall Armstrong
• 金额: $ 21.54万
• 依托单位: METRIA INNOVATION, INC.
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8058282
• 关键词: 3-Dimensional; Activities of Daily Living; Affect; Agreement; Businesses; Cardiopulmonary; Clinic; Clinical; Communities; Computer software; Data; Data Collection; Data Reporting; Dependence; Development; Diagnostic; Disease; Environment; Evaluation; Functional disorder; Funding; Gait; Goals; Health Professional; Healthcare; Human; Impairment; Intervention; Laboratory Research; Lead; Lighting; Measurement; Methods; Moire Patterns; Motion; Movement; Neurologic; Observational Study; Optics; Orthopedics; Outcome; Patients; Persons; Phase; Physical therapy; Population; Positioning Attribute; Protocols documentation; Rehabilitation therapy; Resolution; Role; Site; Small Business Innovation Research Grant; Staging; System; Technical Expertise; Technology; Testing; Time; Validity and Reliability; Video Recording; Walking; base; clinical efficacy; clinical research site; commercialization; cost; cost effective; disability; gait examination; improved; innovation; instrument; kinematics; meetings; mortality; neuromuscular; novel; operation; portability; tool; treatment planning; two-dimensional

DESCRIPTION (provided by applicant): The overall goal of this SBIR Phase I proposal is to establish the measurement reliability and the clinical feasibility of the RGR-GAIT instrumented gait analysis system. Gait dysfunction can dramatically affect a person's ability to perform activities of daily living, and assessment of gait is a critical component of physical therapy practice. Currently, instrumented gait analysis is inaccessible to the vast majority of physical therapy clinics. Because of this, most clinicians depend on observational gait analysis, which has been shown to have inadequate reliability and validity. Further, two-dimensional gait analysis does not capture many critical three- dimensional (3-D) gait features. Clinical outcomes could be improved if three-dimensional gait deviations could be more objectively quantified in a typical clinic, but current 3-D systems are too space intensive, costly, and technically demanding. The Retro-Grate Reflector (RGR) 3-D motion capture system is a novel single-camera 3-D motion tracking technology that fills the gap between clinical need and currently available 3-D systems. Through innovation in the use of moire patterns generated by a lightweight, multi-layer passive optical target, the RGR technology is able to determine 3-D information with a single camera. The RGR system's single camera operation, automatic tracking of multiple targets and robustness to lighting conditions make it less technically demanding and overcomes the barriers for broad clinical use of instrumented gait analysis. Metria Innovation is developing the RGR-GAIT system for clinical deployment. The two aims of this proposal are to establish the inter-trial, inter-session, and inter-tester repeatability and to demonstrate the clinical feasibility of the RGR-GAIT system. A system will be constructed and deployed to a physical therapy clinic where the testing will take place. For the first aim, two therapists will collect 3-D gait data on ten healthy subjects across two days. In addition, ten orthopedic patients will be assessed by two therapists on a single day. These reliability data will inform aim 2, which will objectively quantify gait deviations in the ten orthopedic patients. The results of this study will lead to Phase II, which will focus on establishing measurement reliability between clinical sites and within clinical populations. Phase II will also refine the technology, software, and technical support for full commercialization. PUBLIC HEALTH RELEVANCE: Assessment of walking is a critical component of rehabilitation for a variety of orthopedic, neurological, and cardiopulmonary conditions. Improved assessment of walking and other movement in the clinical setting can dramatically improve patient outcomes and reduce costs by improving treatment planning. The result of this project will be an innovative gait analysis system to meet this need.

描述（由申请人提供）：该SBIR I期建议的总体目标是建立RGR-Gait仪器步态分析系统的测量可靠性和临床可行性。步态功能障碍会极大地影响一个人进行日常生活活动的能力，而步态评估是物理治疗实践的关键组成部分。目前，仪器步态分析对于绝大多数物理疗法诊所都无法访问。因此，大多数临床医生都依赖观察步态分析，这已证明可靠性和有效性不足。此外，二维步态分析不会捕获许多关键的三维步态特征。如果在典型的诊所中可以更客观地量化三维步态偏差，但是当前的3-D系统过于太空，昂贵且技术要求过多，则可以改善临床结果。复古颗粒反射器（RGR）3-D运动捕获系统是一种新型的单相机3-D运动跟踪技术，可填补临床需求与当前可用的3D系统之间的空白。通过创新使用由轻巧的多层无源光目标生成的Moire模式，RGR技术能够使用单个相机来确定3-D信息。 RGR系统的单个摄像头操作，对多个目标的自动跟踪以及对照明条件的鲁棒性使其在技术上的要求降低，并克服了仪器步态分析的广泛临床使用的障碍。 Metria Innovation正在开发用于临床部署的RGR对准系统。该提案的两个目的是建立审判，间歇性和中期可重复性，并证明RGR基准系统的临床可行性。系统将被构建并部署到将进行测试的物理治疗诊所。对于第一个目标，两名治疗师将在两天内收集有关十个健康受试者的3-D步态数据。此外，两名治疗师将在一天中评估10名骨科患者。这些可靠性数据将告知AIM 2，这将客观地量化十个骨科患者的步态偏差。这项研究的结果将导致第二阶段，该期将着重于建立临床部位和临床人群之间的测量可靠性。第二阶段还将完善全面商业化的技术，软件和技术支持。 公共卫生相关性：步行评估是各种骨科，神经系统和心肺疾病的康复的关键组成部分。改进对临床环境中步行和其他运动的评估可以大大改善患者的预后，并通过改善治疗计划来降低成本。该项目的结果将是一种创新的步态分析系统，以满足这一需求。