ALCOHOL DRINKING IN AFFILIATIVE RODENTS

附属啮齿动物的饮酒情况

• 批准号: 8172404
• 负责人: Larry J Young
• 金额: $ 3.29万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172404
• 关键词: Alcohol consumption; Alcohols; Animal Model; Animals; Computer Retrieval of Information on Scientific Projects Database; Funding; Goals; Grant; Health Sciences; Institution; Microtus; Neurologic; Oregon; Reporting; Research; Research Personnel; Resources; Rewards; Rodent; Series; Source; United States National Institutes of Health; Universities; affiliative behavior; design; prairie vole; social

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. During the reporting period, we continued to maintain a stock of Meadow voles which have been available to our collaborator at Oregon Health and Sciences University as needed. The subcontract is designed to provide meadow voles for the core project. These voles have and will continue to be used as an animal model to examine the relationship between affiliative behavior and alcohol consumption. Monogamous prairie voles are highly social and consume much higher amounts of alcohol than other rodents. The hypothesis is that similar neurological mechanisms regulate the rewarding aspects of alcohol use and affiliative behavior and therefore animals that are more affiliative will display higher alcohol intake. A series of studies in prairie voles has and is underway at the Oregon Health and Sciences University to examine the relationship between affiliative behavior and alcohol consumption in prairie voles. The project at Yerkes is a subcontract of the larger project and has examined alcohol consumption in relatively asocial meadow voles with the goal of comparing alcohol intake with prairie voles.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 在报告期间，我们继续维持草地田鼠的库存，根据需要，我们的俄勒冈州健康与科学大学合作者可以使用。 分包合同旨在为核心项目提供草地田鼠。 这些田鼠已经并且将继续用作动物模型，以检查从属行为和饮酒之间的关系。 一夫一妻制的草原田鼠是高度社交的，与其他啮齿动物相比，饮酒量更高。 假设是，类似的神经系统机制调节了酒精使用和从属行为的有意义方面，因此更具有隶属关系的动物将显示出更高的酒精摄入量。 俄勒冈州健康与科学大学的草原田鼠已经并且正在进行一系列研究，以研究在草原田鼠的隶属行为与饮酒之间的关系。 Yerkes的项目是大型项目的分包合同，并且已经检查了相对不可抗化的草地田鼠的酒精消耗，目的是将酒精摄入量与草原田鼠进行比较。