High-risk Establishments and Women's HIV Prevention in Southern China

华南地区高危场所与女性艾滋病预防

• 批准号: 8016607
• 负责人: MARGARET R. WEEKS
• 金额: $ 50.71万
• 依托单位: INSTITUTE FOR COMMUNITY RESEARCH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8016607
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Adoption; Affect; Africa; African; Area; Asians; Award; Beauty; Behavior Therapy; Behavior assessment; Behavioral; Centers for Disease Control and Prevention (U.S.); Characteristics; China; Chinese People; Cities; Collaborations; Communities; Community Health; Country; County; Cross-Sectional Studies; Data; Development; Disease; Documentation; Economic Conditions; Economic Development; Economics; Effectiveness; Environment; Epidemic; Epidemiology; Ethnography; Evaluation; Experimental Designs; Exposure to; Factor Analysis; Female; Female Condoms; Government; Growth; HIV; HIV/STD; Health; Health Promotion; Home environment; Individual; Industry; Infection; Institutes; International; Intervention; Knowledge; Location; Male Condoms; Marketing; Massage; Measures; Methods; Natural regeneration; Nature; Nomads; Outcome; Participant; Pattern; Phase; Population; Prevention; Principal Investigator; Process; Prophylactic treatment; Prostitution; Province; Public Health; Research; Research Personnel; Resources; Restaurants; Risk; Running; Rural; Sample Size; Sampling; Site; Social Change; Social Environment; Social Problems; Social Values; Testing; Time; Treatment Efficacy; Variant; Woman; Work; base; community intervention; comparative; condoms; contextual factors; cost; design; enhancing factor; experience; fight against; high risk; innovation; male; medical schools; microbicide; model design; phase 2 study; population migration; prevent; programs; sex; social; therapy design; tool; transmission process; willingness

DESCRIPTION (provided by applicant): This 5-year study, entitled "High-risk Establishments and Women's HIV Prevention in Southern China," is a Phase I/Phase II study of HIV risk and social dynamics in sex-work establishments, and the development and evaluation of a multi-level, site-based intervention conducted within those establishments to promote use of the female condom (FC) for HIV/STD prevention among women who work there. Based on a collaboration developed through an AIDS-FIRCA study, U.S. and Chinese investigators will work with Hainan and Guanxi provincial CDCs and local communities to conduct the study in two rural and two mid-sized urban towns in these provinces. The study aims are: 1) to assess the number and nature of sex-work establishments in these towns, and the stability and social dynamics within these establishments that affect delivery and testing of a site-base intervention to promote FC use for HIV prevention; 2) to assess factors associated with HIV risk and use of female and male condoms for HIV prevention among women who work within these establishments; 3) to develop, pilot, conduct a process evaluation, assess short-term efficacy and potential sustainability of, and manualize a site-based, multi-level (individual, site, community) intervention conducted in these establishments to promote the FC for HIV/STD prevention, and 4) to explore factors likely to explain: a) variation in feasibility, acceptability, and fidelity of intervention delivered in different establishments and different towns, and b) variation in short-term efficacy and sustainability of the intervention among women in different establishments and different towns. In each town we will use intensive ethnography to assess the characteristics and dynamics of sex workers and sex-work establishments, as well as the feasibility, process, and outcomes of the intervention conducted in those establishments. We will conduct cross-sectional surveys of sex workers in all 4 towns at three time points (baseline, 6 and 12 months post-baseline) for comparative analyses to assess town-level, sex-work establishment, and individual-level characteristics associated with HIV risk and prevention and outcomes of the intervention. Qualitative and quantitative data will be triangulated to build the strongest assessment of characteristics that affect risk and intervention outcomes and to provide the most comprehensive analysis of factors that enhance or impede use of the FC and other prevention measures by women in these establishments. Development and testing of the FC intervention has significant public health implications because of its potential for reducing sexual HIV transmission in this high-risk population and in the broader population of their sexual networks.

描述（由申请人提供）：这项为期5年的研究，题为“中国南部的高风险机构和妇女的艾滋病毒预防”，是对性工作机构中HIV风险和社会动态的I阶段/第二阶段研究，以及对这些机构在这些机构内进行多层次的，基于现场的干预措施的开发和评估，以促进女性（FC/fc/ste）的使用，以促进HIV/STED Preventions中的女性使用。根据通过AIDS-FIRCA研究开发的合作，美国和中国的研究人员将与Hainan和Guanxi省级疾病预防控制中心和当地社区合作，在这些省的两个农村和两个中型城镇中进行这项研究。该研究的目的是：1）评估这些城镇中性工作机构的数量和性质，以及这些机构中影响现场干预的交付和测试以促进FC预防艾滋病毒的使用的稳定和社会动态； 2）评估与艾滋病毒风险以及在这些机构工作的妇女中使用艾滋病毒风险和使用女性和男性避孕套相关的因素； 3）开发，试验，进行过程评估，评估短期疗效和潜在的可持续性，并在这些机构中进行基于站点的，基于站点的多层次（个人，站点，社区）干预措施，以促进HIV/STD预防FC的FC，以及4），以探索以下方面的变化：不同机构和不同城镇中妇女干预的功效和可持续性。在每个城镇，我们将使用密集的人种志评估性工作者和性工作机构的特征和动态，以及这些机构进行的干预措施的可行性，过程和结果。我们将以三个时间点（基线，6个月和12个月的基线）对性工作者进行性工作者的横断面调查，以评估与HIV风险和预防和预防和干预措施相关的城镇级别，性工作机构以及个人级别的特征。定性数据和定量数据将进行三角测量，以对影响风险和干预结果的特征进行最强的评估，并对这些机构中女性对FC和其他预防措施的使用最全面分析。 FC干预的开发和测试具有重大的公共卫生影响，因为它有可能减少这种高风险人群以及更广泛的性网络人口的性HIV传播。

项目成果

Who are the preferential targets for intervention programs related to the female condom among sex workers in southern China?

南方性工作者女用安全套干预项目的优先对象是哪些人？

• DOI: 10.1521/aeap.2013.25.4.349
• 发表时间: 2013
• 期刊: AIDS education and prevention : official publication of the International Society for AIDS Education
• 作者: Wang,Yanhong;Liao,Susu;Jiang,Jingmei;Weeks,MargaretR;Nie,Li;Li,Jianghong;He,Bin;Zhou,Yuejiao;Li,Fei;Dunn,Jennifer;Zhang,Qingning
• 通讯作者: Zhang,Qingning