MARC - DEVELOPING BIOINFORMATICS PROGRAMS, JULY 9 - 20, 2007

MARC - 开发生物信息学项目，2007 年 7 月 9 日至 20 日

• 批准号: 7956289
• 负责人: HUGH B NICHOLAS
• 金额: $ 0.08万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956289
• 关键词: Algorithms; Bioinformatics; Biological; Biology; Biomedical Research; CCL7 gene; Chemistry; Computer Retrieval of Information on Scientific Projects Database; Databases; Educational process of instructing; Educational workshop; Engineering; Evaluation; Faculty; Foundations; Funding; Goals; Grant; High Performance Computing; Homology Modeling; Individual; Institutes; Institution; Internet; Mathematics; Methods; Participant; Pattern; Physics; Positioning Attribute; Programming Languages; Research; Research Personnel; Resources; Sequence Alignment; Source; Structure; Students; Trees; United States National Institutes of Health; Weight; computer science; interest; markov model; molecular dynamics; programs; statistics; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Summer Institute in Bioinformatics is a two week course, directed towards faculty, students and staff at MARC program institutions. The Summer Institute has the goal of preparing the participants to teach bioinformatics courses at their local campuses. Interested individuals associated with a MARC program institution are encouraged to apply, including faculty from diverse departments, including biology, chemistry, physics, mathematics, statistics, computer science, and engineering. The workshop will introduce participants to the computational, mathematical and biological issues surrounding bioinformatics. A number of fundamental topics in bioinformatics will be discussed including inferring structures and functions; database searching and pairwise sequence alignment; multiple sequence alignments; pattern identification. Special emphasis will be placed on parameter selection, and the mathematical, statistical, and biological foundations of the algorithms and methods presented. Information will also be provided on hidden Markov models, advanced position-specific weight matrices, bayesian estimation, homology modeling, structural biology, molecular dynamics simulations, and phylogenic tree creation and evaluation. The use of internet resources and remote computing facilities will also be discussed as will an introduction Biology for non-biologists and an introduction to the PERL programming language for biologists.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 生物信息学暑期学院为期两周，面向 MARC 项目机构的教师、学生和工作人员。暑期学院的目标是让参与者做好在当地校园教授生物信息学课程的准备。我们鼓励与 MARC 项目机构相关的感兴趣的个人申请，包括来自生物学、化学、物理、数学、统计学、计算机科学和工程等不同院系的教师。 该研讨会将向参与者介绍围绕生物信息学的计算、数学和生物学问题。将讨论生物信息学的许多基本主题，包括推断结构和功能；数据库搜索和成对序列比对；多重序列比对；模式识别。将特别强调参数选择以及所提出的算法和方法的数学、统计和生物学基础。还将提供有关隐马尔可夫模型、高级特定位置权重矩阵、贝叶斯估计、同源建模、结构生物学、分子动力学模拟以及系统发育树创建和评估的信息。还将讨论互联网资源和远程计算设施的使用，以及针对非生物学家的生物学介绍和针对生物学家的 PERL 编程语言介绍。