IDENTIFICATION OF IFT PARTICLE COMPONENTS

IFT 颗粒成分的识别

• 批准号: 7957780
• 负责人: Piali Sengupta
• 金额: $ 0.33万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7957780
• 关键词: Biology; Caenorhabditis elegans; Cilia; Computer Retrieval of Information on Scientific Projects Database; Functional disorder; Funding; Fungal Genome; Goals; Grant; Institution; Mass Spectrum Analysis; Process; Research; Research Personnel; Resources; Source; Structure; United States National Institutes of Health; developmental disease; particle

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of our research is to understand how ciliary structures are generated, and how they function. We are exploring this issue in C. elegans. All cilia are formed by the process of intraflagellar transport (IFT). We will use mass spectrometry to identify IFT particle components from C. elegans cilia. We expect that identification of new ciliary components will allow us to further understand how ciliary dysfunction leads to developmental disorders.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 The goal of our research is to understand how ciliary structures are generated, and how they function. We are exploring this issue in C. elegans. All cilia are formed by the process of intraflagellar transport (IFT). We will use mass spectrometry to identify IFT particle components from C. elegans cilia.我们希望鉴定新的睫状成分将使我们能够进一步了解睫状功能障碍如何导致发育障碍。