Creating A Biomarker Registry for Secondary Data Collections

为二次数据收集创建生物标志物注册表

基本信息

批准号：
7915666
负责人：
JAMES W MCNALLY
金额：
$ 19万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-08-15 至 2011-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7915666
关键词：
Access to Information Address Age Aging Agreement Archives Bibliography Biological Biological Markers Biological Process Biosocial Blood Body mass index Cataloging Catalogs Collection Communities Data Data Collection Data Set Development Diagnosis Evaluation Funding Goals Growth Health Housing Individual Information Resources Lead Life Literature Longitudinal Studies Mainstreaming Measures Medical Metadata Methodology Mission Modeling National Health and Nutrition Examination Survey Obesity Outcome Plasma Process Protocols documentation Registries Request for Applications Research Research Personnel Retirement Sampling Science Social Environment Specific qualifier value Spottings Surveys Swab System Testing United States National Institutes of Health Universities Vagina Women&apos s Health Work base computerized information organization interest nutrition programs research study social socioeconomics tool virtual web site

项目摘要

DESCRIPTION (provided by applicant): This application requests R21 exploratory funds to develop methodology and tools leading to a comprehensive registry of biomarker and health variables found in publicly available secondary data collections. The proposed pilot will begin with data drawn from collections maintained by the National Archive of Computerized Data on Aging (NACDA) and the Inter-University Consortium of Social and Political Science (ICPSR). We will use this base to establish protocols to review and identify variables in other collections that measure biological and medical indicators commonly referred to as biomarkers allowing us to create a comprehensive registry of such indicators for public use. Increasingly variables defined as biomarkers are routinely collected as part of many surveys; this application is the first to propose an effective approach for organizing this growing universe of information into a registry system and to promote the use of these data for secondary research. The evaluation and identification process proposed for year one will establish a framework that, in the second year, will establish a broad system to incorporate biomarker information from data collections maintained both within NACDA and outside our established archives. Project Narrative: This work addresses the organization of research data to provide access to and information on biological and medical indicators of health. The project will help researchers develop original research that studies the impacts of medical tests, obesity and other health factors on the lives of individuals.

描述（由申请人提供）：本申请请求 R21 探索性资金来开发方法和工具，从而对公开的二级数据集中发现的生物标志物和健康变量进行全面登记。拟议的试点将从国家老龄化计算机化数据档案馆（NACDA）和社会与政治科学大学间联盟（ICPSR）维护的馆藏中提取数据开始。我们将利用这个基础建立协议来审查和识别其他集合中的变量，这些变量测量通常称为生物标志物的生物和医学指标，使我们能够创建此类指标的综合登记册以供公众使用。作为许多调查的一部分，越来越多的被定义为生物标志物的变量被常规收集；该应用程序首次提出了一种有效方法，将不断增长的信息组织到登记系统中，并促进这些数据用于二次研究。第一年提出的评估和识别过程将建立一个框架，第二年将建立一个广泛的系统，以纳入来自 NACDA 内部和我们既定档案之外的数据收集的生物标志物信息。项目叙述：这项工作致力于组织研究数据，以提供有关健康的生物和医学指标的访问和信息。该项目将帮助研究人员开展原创研究，研究医学检查、肥胖和其他健康因素对个人生活的影响。