Cloning of molecular targets of CMI in type 1 diabetes

1型糖尿病CMI分子靶点的克隆

• 批准号: 8038522
• 负责人: HOWARD W DAVIDSON
• 金额: $ 22.33万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-14 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8038522
• 关键词: Ablation; Animal Model; Antigens; Appearance; Attention; Autoantibodies; Autoantigens; Autoimmune Diseases; Biological Markers; Breeding; CD4 Positive T Lymphocytes; CD8B1 gene; Cells; Cellular Immunity; Child; Chronic Disease; Clinical; Clinical Trials; Cloning; Conduct Clinical Trials; DNA; Data; Development; Disease; Disease Progression; Drug Design; Elderly; Epitopes; Funding; Genetic; Goals; Haplotypes; Human; Inbred NOD Mice; Incidence; Individual; Insulin; Insulin-Dependent Diabetes Mellitus; Intervention; Knowledge; Laboratories; Molecular Target; Mus; NOD/SCID mouse; Natural History; Organ; Pancreas; Peptides; Pharmaceutical Preparations; Population; Pre-Clinical Model; Prevention; Process; Protocols documentation; Reagent; Research; Role; Specificity; T-Cell Receptor; T-Lymphocyte; T-Lymphocyte Epitopes; Testing; Therapeutic; Time; To autoantigen; Translating; Vaccination; autoreactive T cell; base; diabetic; disease natural history; high risk; insight; intervention effect; member; new therapeutic target; novel therapeutic intervention; preclinical study; prevent; research study; response; success; therapeutic target; young adult; zinc-binding protein