LSU DENTAL COBRE: STATISTICAL CORE

路易斯安那州立大学牙科 COBRE：统计核心

• 批准号: 7720558
• 负责人: Donald E Mercante
• 金额: $ 16.89万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7720558
• 关键词: Area; Arts; Centers of Research Excellence; Chalk; Clinical Trials Database; Computer Retrieval of Information on Scientific Projects Database; Consultations; Data; Data Analyses; Database Management Systems; Databases; Dental; Development; District of Columbia; Epidemiologic Studies; Experimental Designs; Funding; Grant; Husband; Institution; Measures; Mentors; Methodology; Mission; Paper; Preparation; Principal Investigator; Procedures; Process; Quality Control; Recruitment Activity; Research; Research Design; Research Personnel; Research Proposals; Resources; Role; Sample Size; Series; Services; Source; Statistical Methods; Structure; United States National Institutes of Health; Work; abstracting; design; interest; lectures; member; statistical service; statistics; Area; Arts; Centers of Research Excellence; Chalk; Clinical Trials Database; Computer Retrieval of Information on Scientific Projects Database; Consultations; Data; Data Analyses; Database Management Systems; Databases; Dental; Development; District of Columbia; Epidemiologic Studies; Experimental Designs; Funding; Grant; Husband; Institution; Measures; Mentors; Methodology; Mission; Paper; Preparation; Principal Investigator; Procedures; Process; Quality Control; Recruitment Activity; Research; Research Design; Research Personnel; Research Proposals; Resources; Role; Sample Size; Series; Services; Source; Statistical Methods; Structure; United States National Institutes of Health; Work; abstracting; design; interest; lectures; member; statistical service; statistics

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Introduction: The overall mission of the Statistical Core is to provide support in the areas of study design, sample size estimation/statistical power analyses, statistical methodology and database management for the projects in the COBRE. The Statistical Core has a crucial role in not only providing statistical services but in contributing to the mentoring process for the junior principal investigators (JPIs) in developing their understanding of the importance of study design and data analysis. Objective: The activities of the Statistical Core are guided by the following 5 specific aims. (1) Consultation with Junior Principle Investigators (JPIs) on study design, sample size estimation, statistical analysis plan, and research proposal. (2) Development and management of database management system and quality control procedures. (3) Statistical analysis of study data, presentation and interpretation of results. (4) Educational services to support investigator development in study design and analysis. (5) Enhancement of statistical core services to bring state of the art capabilities to the COBRE. Methods: The Statistical Core members (Drs. Mercante, Peters, and Simonsen, and Mr. Hagan) regularly attend seminars, chalk talks, grantseekers, invited talks presented by or at the request of the JPIs. In addition, Dr. Mercante regularly attends secondary mentor meetings for the JPIs. Members of the Statistical Core are available to each JPI to review and advise JPIs on grant submissions, abstract and paper preparations and submission. All members of the Statistical Core actively participate in developing and presenting lectures in a 10-part didactic series specifically structured to meet the needs and interests of the current JPI team. Results: The Statistical Core successfully recruited a M.S. biostatistician, Mr. Joseph Hagan, into the Statistical Core to take over the responsibilities Ms. Joanna Du, who resigned in late 2007 when her husband was relocated to Washington, D.C. Drs. Mercante, Peters, and Simonsen and Mr Joe Hagan all presented seminars as part of the didactic series to the JPIs. Topics included basic epidemiological study design and measures, design and analysis issues in statistics and clinical trials, and database management. Dr. Mercante has collaborated with Dr. Xu on his grant submission and re-submission, providing advice on experimental design, sample size estimation and statistical analysis. Discussion: The Statistical Core has made significant progress towards the stated objectives and will continue to work closely with the JPIs to provide guidance and support for their research. In particular, the Statistical Core has greatly expanded and enhanced its didactic series and website for providing statistical resources to the JPIs. Dr. Mercante has met with Dr. Xu on multiple occasions to discuss enhanced statistical support of his R01 application.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 简介：统计核心的总体使命是为毛cr中项目的项目设计，样本量估计/统计能力分析，统计方法论和数据库管理提供支持。统计核心不仅在提供统计服务，而且在为初级首席研究人员（JPIS）的指导过程中做出贡献方面具有至关重要的作用。 目的：统计核心的活动受到以下5个特定目标的指导。 （1）就研究设计，样本估计，统计分析计划和研究建议与初级原理研究者（JPI）咨询。 （2）数据库管理系统和质量控制程序的开发和管理。 （3）研究数据，结果的介绍和解释的统计分析。 （4）支持研究设计和分析研究人员发展的教育服务。 （5）增强统计核心服务，以将最先进的能力带入鞋底。 方法：统计核心成员（Mercante博士，Peters和Simonsen和Hagan先生）定期参加研讨会，Chalk Talks，Grantseekers，邀请了JPIS或应jpis的要求进行的会谈。此外，Mercante博士定期参加JPIS的次要导师会议。统计核心的成员可供每个JPI审查并就赠款提交，摘要和纸张准备以及提交的赠款提出建议。统计核心的所有成员都积极地参与了一个专门构建的10部分教学系列的开发和介绍，以满足当前JPI团队的需求和利益。 结果：统计核心成功招募了M.S.生物统计学家约瑟夫·哈根（Joseph Hagan）先生进入了统计核心，接管了乔安娜·杜（Joanna Du）女士的责任，乔安娜·杜（Joanna Du）女士于2007年末辞职，当时她的丈夫搬到华盛顿特区。 Mercante，Peters和Simonsen和Joe Hagan先生都向JPIS举办了研讨会，作为Didactic系列的一部分。主题包括基本的流行病学研究设计和措施，统计和临床试验中的设计和分析问题以及数据库管理。 Mercante博士已与Xu博士合作就其赠款提交和重新提取，提供了有关实验设计，样本量估计和统计分析的建议。 讨论：统计核心已向既定目标取得了重大进展，并将继续与JPI紧密合作，为其研究提供指导和支持。特别是，统计核心已大大扩展并增强了其教学系列和网站，以向JPI提供统计资源。 Mercante博士多次与Xu博士会面，讨论了他的R01应用程序的增强统计支持。