Project 6. Ecological Momentary Assessment of Emotional Regulation

项目6.情绪调节的生态瞬时评估

• 批准号: 7555161
• 负责人: Timothy J Trull
• 金额: $ 35.02万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7555161
• 关键词: Acute; Address; Affect; Affective; Alcohol abuse; Alcohol consumption; Alcohol or Other Drugs use; Alcoholism; Alcohols; Antisocial Personality Disorder; Attenuated; Behavior; Behavior Therapy; Biological Models; Blood alcohol level measurement; Body Weight; Borderline Personality Disorder; CCL7 gene; Calculi; Characteristics; Cigarette; Classification; Clinical; Cognitive; Comorbidity; Consumption; Control Groups; Data; Data Analyses; Data Collection; Disease; Disinhibition; Emotional; Emotions; Environment; Etiology; Event; Exhibits; Foundations; Frequencies; Funding; General Population; Grant; Impulsive Behavior; Impulsivity; Individual; Individual Differences; Lead; Life; Limb structure; Maintenance; Mental disorders; Modeling; Moods; Negative Reinforcements; Odds Ratio; Outpatients; Participant; Patients; Pattern; Play; Population; Positive Reinforcements; Prevention; Process; Progress Reports; Psychological reinforcement; Recreation; Regulation; Reporting; Research; Research Personnel; Research Project Grants; Risk; Role; Sampling; Self-Injurious Behavior; Self-control as a personality trait; Smoke; Smoking; Symptoms; Testing; Time; Tobacco use; Training; alcohol effect; alcohol use disorder; base; clinically significant; comparison group; coping; design; drinking; effective therapy; emotion regulation; hangover; hedonic; interest; negative mood; population based; positive emotional state; response; sex; social; theories; trait; treatment strategy

This study extends currently ongoing research on both drinking and smoking (current Project 6) using ecological momentary assessment (EMA) to examine the use of alcohol with and without conjoint smoking to regulate emotions, and the effects of these regulation strategies on subsequent mood. We add a comparison group of Borderline Personality Disorder (BPD) patients. BPD exhibits high comorbidity with alcohol use disorders (AUDs) in both clinical and population-based samples. Cardinal symptoms of BPD, impulsivity and affective instability, are central constructs in theories of AUD etiology, so BPD represents a type of "model system" for studying the role of emotion regulation and disordered self-control in the genesis of AUD. We will collect EMA data from both random and event-based (e.g., drinking, smoking) assessments to address our aims. We will test the following hypotheses: (1) drinking episodes in BPD patients will be presaged by both positive and negative moods; drinking in non-affected controls (CON) will be presaged by positive but not negative moods; impulsivity will moderate these mood-substance use relations. (2) BPD patients' drinking episodes will be associated with heavier consumption (sex and body weight adjusted) than CON; group differences will be moderated by both affective instability and by impulsivity. Drinks consumed will be moderated by number of cigarettes in both groups. (3) Alcohol consumption's effect on mood will be characterized by both positive and negative reinforcement; smoking will attenuate the degree of reinforcement due to acute cross-tolerance effects in both groups. In BPD patients, underlying affective instability will attenuate the duration of alcohol-related, salutary effects on mood. (4) Negative post-drinking effects of alcohol on mood will be larger in BPD patients than controls because of additive effects of hedonic rebound effects of alcohol and negative affectivity in BPD patients; smoking will increase these effects in both groups. This study will provide important information about the role mood dysregulation plays in the etiology and maintenance of AUD, and how impulsivity and smoking may interact with mood dysregulation to lead to increased drinking. These results will have implications for both prevention and treatment of alcohol problems.

这项研究扩展了目前对饮酒和吸烟的正在进行的研究（当前项目6） 生态瞬时评估（EMA）检查在和不吸烟的情况下使用酒精的使用 调节情绪，以及这些法规策略对随后情绪的影响。我们添加了一个比较 边界人格障碍（BPD）患者组。 BPD表现出较高的合并症与酒精使用 临床和基于人群的样本中的疾病（AUDS）。 BPD的基本症状，冲动和 情感不稳定性是AUD病因理论中的核心构造，因此BPD代表了一种类型的“模型 系统“用于研究情绪调节的作用和自我控制在AUD的起源中的作用。我们将 从随机和基于事件的（例如饮酒，吸烟）评估中收集EMA数据，以解决我们的 目标。我们将检验以下假设：（1）BPD患者的饮酒发作将由双方预示 积极和消极的情绪；在非影响对照中饮酒（CON）将由阳性但不是 负面情绪；冲动将减轻这些情绪实质性使用关系。 （2）BPD患者喝酒 发作将与骗局相比，发作与更重的消费（调整性和体重）有关；团体 情感不稳定性和冲动性都将使差异调节。消费的饮料将是 两组中的香烟数量都在主持。 （3）饮酒对情绪的影响将是 以正面和负面的强化为特征；吸烟会衰减 两组的急性交叉耐受作用引起的增强。在BPD患者中，潜在的情感 不稳定性会减轻与酒精相关的，有益于情绪的持续时间。 （4）饮用后负面 BPD患者的酒精对情绪的影响将比对照组大，因为享乐的添加作用 BPD患者的酒精和负面影响的反弹作用；吸烟会增加这些影响 两组。这项研究将提供有关情绪失调作用的重要信息 AUD的病因和维护，以及冲动性和吸烟如何与情绪失调相互作用 导致饮酒增加。这些结果将对酒精的预防和治疗有影响 问题。