Project 6. Ecological Momentary Assessment of Emotional Regulation

项目6.情绪调节的生态瞬时评估

基本信息

批准号：
7555161
负责人：
Timothy J Trull
金额：
$ 35.02万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-30 至 2014-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7555161
关键词：
Acute Address Affect Affective Alcohol abuse Alcohol consumption Alcohol or Other Drugs use Alcoholism Alcohols Antisocial Personality Disorder Attenuated Behavior Behavior Therapy Biological Models Blood alcohol level measurement Body Weight Borderline Personality Disorder CCL7 gene Calculi Characteristics Cigarette Classification Clinical Cognitive Comorbidity Consumption Control Groups Data Data Analyses Data Collection Disease Disinhibition Emotional Emotions Environment Etiology Event Exhibits Foundations Frequencies Funding General Population Grant Impulsive Behavior Impulsivity Individual Individual Differences Lead Life Limb structure Maintenance Mental disorders Modeling Moods Negative Reinforcements Odds Ratio Outpatients Participant Patients Pattern Play Population Positive Reinforcements Prevention Process Progress Reports Psychological reinforcement Recreation Regulation Reporting Research Research Personnel Research Project Grants Risk Role Sampling Self-Injurious Behavior Self-control as a personality trait Smoke Smoking Symptoms Testing Time Tobacco use Training alcohol effect alcohol use disorder base clinically significant comparison group coping design drinking effective therapy emotion regulation hangover hedonic interest negative mood population based positive emotional state response sex social theories trait treatment strategy

Acute Address Affect Affective Alcohol abuse Alcohol consumption Alcohol or Other Drugs use Alcoholism Alcohols Antisocial Personality Disorder Attenuated Behavior Behavior Therapy Biological Models Blood alcohol level measurement Body Weight Borderline Personality Disorder CCL7 gene Calculi Characteristics Cigarette Classification Clinical Cognitive Comorbidity Consumption Control Groups Data Data Analyses Data Collection Disease Disinhibition Emotional Emotions Environment Etiology Event Exhibits Foundations Frequencies Funding General Population Grant Impulsive Behavior Impulsivity Individual Individual Differences Lead Life Limb structure Maintenance Mental disorders Modeling Moods Negative Reinforcements Odds Ratio Outpatients Participant Patients Pattern Play Population Positive Reinforcements Prevention Process Progress Reports Psychological reinforcement Recreation Regulation Reporting Research Research Personnel Research Project Grants Risk Role Sampling Self-Injurious Behavior Self-control as a personality trait Smoke Smoking Symptoms Testing Time Tobacco use Training alcohol effect alcohol use disorder base clinically significant comparison group coping design drinking effective therapy emotion regulation hangover hedonic interest negative mood population based positive emotional state response sex social theories trait treatment strategy

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项目摘要

This study extends currently ongoing research on both drinking and smoking (current Project 6) using ecological momentary assessment (EMA) to examine the use of alcohol with and without conjoint smoking to regulate emotions, and the effects of these regulation strategies on subsequent mood. We add a comparison group of Borderline Personality Disorder (BPD) patients. BPD exhibits high comorbidity with alcohol use disorders (AUDs) in both clinical and population-based samples. Cardinal symptoms of BPD, impulsivity and affective instability, are central constructs in theories of AUD etiology, so BPD represents a type of "model system" for studying the role of emotion regulation and disordered self-control in the genesis of AUD. We will collect EMA data from both random and event-based (e.g., drinking, smoking) assessments to address our aims. We will test the following hypotheses: (1) drinking episodes in BPD patients will be presaged by both positive and negative moods; drinking in non-affected controls (CON) will be presaged by positive but not negative moods; impulsivity will moderate these mood-substance use relations. (2) BPD patients' drinking episodes will be associated with heavier consumption (sex and body weight adjusted) than CON; group differences will be moderated by both affective instability and by impulsivity. Drinks consumed will be moderated by number of cigarettes in both groups. (3) Alcohol consumption's effect on mood will be characterized by both positive and negative reinforcement; smoking will attenuate the degree of reinforcement due to acute cross-tolerance effects in both groups. In BPD patients, underlying affective instability will attenuate the duration of alcohol-related, salutary effects on mood. (4) Negative post-drinking effects of alcohol on mood will be larger in BPD patients than controls because of additive effects of hedonic rebound effects of alcohol and negative affectivity in BPD patients; smoking will increase these effects in both groups. This study will provide important information about the role mood dysregulation plays in the etiology and maintenance of AUD, and how impulsivity and smoking may interact with mood dysregulation to lead to increased drinking. These results will have implications for both prevention and treatment of alcohol problems.

这项研究扩展了目前对饮酒和吸烟的正在进行的研究（当前项目6）生态瞬时评估（EMA）检查在和不吸烟的情况下使用酒精的使用调节情绪，以及这些法规策略对随后情绪的影响。我们添加了一个比较边界人格障碍（BPD）患者组。 BPD表现出较高的合并症与酒精使用临床和基于人群的样本中的疾病（AUDS）。 BPD的基本症状，冲动和情感不稳定性是AUD病因理论中的核心构造，因此BPD代表了一种类型的“模型系统“用于研究情绪调节的作用和自我控制在AUD的起源中的作用。我们将从随机和基于事件的（例如饮酒，吸烟）评估中收集EMA数据，以解决我们的目标。我们将检验以下假设：（1）BPD患者的饮酒发作将由双方预示积极和消极的情绪；在非影响对照中饮酒（CON）将由阳性但不是负面情绪；冲动将减轻这些情绪实质性使用关系。（2）BPD患者喝酒发作将与骗局相比，发作与更重的消费（调整性和体重）有关；团体情感不稳定性和冲动性都将使差异调节。消费的饮料将是两组中的香烟数量都在主持。（3）饮酒对情绪的影响将是以正面和负面的强化为特征；吸烟会衰减两组的急性交叉耐受作用引起的增强。在BPD患者中，潜在的情感不稳定性会减轻与酒精相关的，有益于情绪的持续时间。（4）饮用后负面 BPD患者的酒精对情绪的影响将比对照组大，因为享乐的添加作用 BPD患者的酒精和负面影响的反弹作用；吸烟会增加这些影响两组。这项研究将提供有关情绪失调作用的重要信息 AUD的病因和维护，以及冲动性和吸烟如何与情绪失调相互作用导致饮酒增加。这些结果将对酒精的预防和治疗有影响问题。