Directed Reconfigurable Nanomachines

定向可重构纳米机器

基本信息

批准号：
EP/F010109/1
负责人：
Ashley Cadby
金额：
$ 10.27万
依托单位：
University of Sheffield
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2008
资助国家：
英国
起止时间：
2008 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=EP%2FF010109%2F1
关键词：
Directed Reconfigurable Nanomachines

项目摘要

Directed Reconfigurable NanomachinesWe propose a scheme to revolutionise the synthesis of nanodevices, nanomachines, and, ultimately, functional materials via the positional assembly of molecules and nanoscale building blocks. Computer-directed actuators will be used to drive (with sub-nanometre to sub-Angstrom precision) the elements of a nanosystem along pre-defined and entirely deterministic trajectories, thereby achieving structures not accessible by mimicking natural assembly strategies alone. Linkages and bonding between the building blocks will also be initiated, modulated, and - in some cases - terminated by direct computer control. Our proposal rests on the parallel development of novel surface-bound, reconfigurable nanoscale building blocks (molecules, functionalised clusters, nanoparticles) and advanced techniques for automated assembly of matter. We focus on the generation of two major and immensely challenging functionalities for positionally-assembled nanomachines: switchable energy transduction and conformationally-driven motion. Our archetypal system comprises the following units: an energy harvester, a switchable/gateable link, and an optical or mechanical output. By arranging, configuring, and triggering these fundamental units our long-term goal is no less than the fabrication of an autonomous, abiotic nanomachine.

定向可重构纳米机器我们提出了一种方案，通过分子和纳米级构建块的位置组装，彻底改变纳米器件、纳米机器以及最终功能材料的合成。计算机控制的执行器将用于沿着预定义和完全确定性的轨迹驱动（以亚纳米到亚埃的精度）纳米系统的元件，从而实现仅通过模仿自然组装策略无法实现的结构。构建块之间的链接和结合也将通过直接计算机控制来启动、调节和（在某些情况下）终止。我们的建议基于新型表面结合、可重构纳米级构建块（分子、功能化簇、纳米颗粒）和物质自动组装先进技术的并行开发。我们专注于为位置组装的纳米机器生成两个主要且极具挑战性的功能：可切换的能量转换和构象驱动的运动。我们的原型系统包括以下单元：能量采集器、可切换/可门控链路以及光学或机械输出。通过安排、配置和触发这些基本单元，我们的长期目标不亚于制造自主的非生物纳米机器。