RECRUITING CORE

招聘核心人员

• 批准号: 7381146
• 负责人: J Donald Capra
• 金额: $ 29.7万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381146
• 关键词: RECRUITING; CORE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The selection of the five recruiting packages for this application was an exacting and laborious process. Each of the program heads made a half-day presentation to the steering committee of the present COBRE grant. Drs. Tang, Floyd, Harley, Gorbsky and Kincade argued for a position in their programs. After institutional resources, space and direction was approved, descriptions of the recruits were solicited. We endeavored to recruit scientists jointly whenever possible, as illustrated by the Neuroimmunologist being recruited by the Programs in FRBA/A&I, and the Molecular Biologist being recruited by the Programs in MCDB/I&C (see Recruiting Core, this application). Such joint recruits act to integrate research in individual Programs, serving as conduits between them. Integration of this kind strengthens the researcher by placing him/her in dual research environments, the Programs involved, and the institution as a whole. Importantly, this integration plays a vital role in allowing us to assemble diverse teams of researchers to target complex goals, as illustrated by our emerging Neuroscience Initiative and recent successful U19 award. In each instance, we have provided within the application the justification for the recruit, who will mentor the recruit, and the exact plans for the recruit within our organizational framework. We have also taken heed of the current guidelines that allow at least some allocation of resources to others in an institution not directly connected to the narrow focus of the COBRE program under review. As such, following with our long-range strategic plan to add to our faculty in neuroscience and cell, molecular and developmental biology, we are using four of the recruiting packages to support those efforts. 1) Joint Appointment for a Neuro-immunologist in Free Radical Biology and Aging Program and the Arthritis and Immunology Research Program: OMRF has an outstanding program in Free Radical Biology and Aging. The current six members of the program focus effort on the neuroinflammation that accompanies Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS). We believe expanding this program by four investigators will bring us to a critical mass in this arena. OMRF also has an outstanding program in Arthritis and Immunology (Drs. James, Harley, Reichlin, Farris, Centola, etc). We have determined that a joint recruit between these two programs would benefit both, and foster communication between two of our highly successful research efforts. The two Programs have determined that such a recruit should be a neuro-immunologist, and it is to support this recruit that we are requesting funds. The full justification for the recruit is found within. Dr. Robert Floyd, head of FRBA, and Dr. Judith James of AI will mentor this recruit. Dr. Kenneth Hensley will serve as junior mentor. Dr. Hensley has been on our faculty for five years, has an R01, and is one of our most cited young investigators. The Steering Committee believes he is ready for this role. We will also enlist the expertise of Dr. Rheal Towner and Dr. Mark Coggeshall (head of the Cell Signaling Core on this application). 2) Addition to the Immunobiology and Cancer Program: Dr. Paul Kincade heads OMRF's Immunobiology and Cancer program. His two recruits over the last seven years, Drs. Mark Coggeshall and Xiao Hong Sun, are among the best additions to our staff in the last decade. Both have successfully transitioned their laboratories to OMRF, both have successfully competed on a national level for funds (six R01s between them), and both have been promoted to full member status. The five-person program (with Drs. Webb and Thompson) deserves an additional colleague. They have outlined in the section on recruiting cores the logic for their choices and the people they will be recruiting. Indeed, this search is well under way. Depending on the recruit, this mentee will be mentored by any member of this distinguished faculty. Likely, Dr. Kincade will take the senior mentorship role and Dr. Sun a junior mentor role. 3) Addition to the Molecular, Cell and Developmental Biology Research Program: A year ago, OMRF recruited Dr. Gary Gorbsky as the new head of MCDB. He is in the process of recruiting new faculty for his program. The major emphasis of the early recruiting will be to add to our strength in developmental biology, especially as we have a world class mouse facility that is functioning well. We have support from the Presbyterian Health Foundation to help recruit individuals with an emphasis in genetics, and seek support from this COBRE to recruit a faculty member with a developmental biology interest, especially one who would collaborate with members of our outstanding Cardiovascular Research Program, Arthritis and Immunology Research Program, or Neuroscience Research Initiative. This recruit falls under the new guidelines for the COBRE that allow recruiting outside the major theme of the COBRE. We will be certain that this recruit is well mentored, and the recruit will have full access to our Core Facilities. This will provide a formal mechanism to include this recruit in the COBRE process. Obviously, the Steering Committee, our External Advisory Committee as well as NCRR will be approached for guidance. 4) Joint appointment to the Immunobiology and Cancer Program and the Molecular Cell and Developmental Biology Research Program: The goal of this recruitment would be to bring someone to our campus who will bridge the research interests of two of our finest programs: IC and MCDB. Here we seek to identify someone who (for example) performs studies employing genetic manipulation of the developing immune system of the mouse, perhaps on the B cell or the T cell side, as we have great depth in B and T cell development, but not at the genetic level. Such a person would fit comfortably in both programs and serve as a conduit for interaction between them. Drs. Kincade and Gorbsky have agreed to undertake this joint recruitment. 5) Addition to the Free Radical Biology and Aging Program: We seek funds to fill a major void at OMRF: a mathematical modeler (with an emphasis in neurobiology). The addition of Dr. Jose Conchello, a mathematician in our imaging group in our Molecular Cell and Developmental Biology Program has impacted our entire Institute, and we seek funds to extend this level of mathematical expertise into neurobiology. The individual who assumes this position will be collaborating with a group of experienced neuroscience researchers already in place at OMRF and OUHSC. We believe this powerful technology needs to be present on our campus and located in the FRBA program. More details are enclosed within. Mentoring someone like this will be complex, as we have no comparable talent at OMRF, however Dr. Thomas Ray, an internationally recognized researcher in the field of computer modeling is located nearby at the University of Oklahoma Norman Campus. Oklahoma. Dr. Conchello as well as Drs. Floyd and Tang should provide the senior level of mentorship we need. If needed we will bring someone here from outside the state on a regular basis to provide mentoring for the recruit.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。本次申请的五种招聘方案的选择是一个严格而费力的过程。每位项目负责人都向指导委员会做了半天的介绍，介绍了当前 COBRE 赠款的情况。博士。唐、弗洛伊德、哈雷、戈尔布斯基和金凯德在他们的项目中争夺一席之地。在机构资源、空间和方向获得批准后，就征集了新成员的描述。我们努力尽可能联合招募科学家，如 FRBA/A&I 项目招募的神经免疫学家和 MCDB/I&C 项目招募的分子生物学家（请参阅本申请的招募核心）。这种联合招募的作用是将研究整合到各个项目中，充当它们之间的渠道。这种整合通过将研究人员置于双重研究环境、所涉及的项目和整个机构中来增强研究人员的能力。重要的是，这种整合在让我们能够组建不同的研究团队来实现复杂的目标方面发挥着至关重要的作用，正如我们新兴的神经科学计划和最近成功的 U19 奖项所表明的那样。 在每种情况下，我们都在申请中提供了招聘理由、谁将指导招聘人员以及我们组织框架内招聘的确切计划。 我们还注意到了当前的指导方针，该指导方针至少允许将部分资源分配给与正在审查的 COBRE 计划的狭隘关注点没有直接关系的机构中的其他人。因此，根据我们增加神经科学和细胞、分子和发育生物学教师队伍的长期战略计划，我们正在使用四个招聘计划来支持这些努力。 1) 自由基生物学和衰老项目以及关节炎和免疫学研究项目联合任命神经免疫学家：OMRF 在自由基生物学和衰老方面拥有出色的项目。该项目目前的六名成员主要致力于治疗帕金森病、阿尔茨海默病和肌萎缩侧索硬化症 (ALS) 相关的神经炎症。我们相信，通过四名研究人员扩大该计划将使我们在这个领域达到临界规模。 OMRF 在关节炎和免疫学方面也有出色的项目（James、Harley、Reichlin、Farris、Centola 博士等）。我们已经确定，这两个项目之间的联合招募将使双方受益，并促进我们两个非常成功的研究工作之间的沟通。这两个计划已确定此类招募人员应为神经免疫学家，我们正在申请资金来支持该招募人员。招募的完整理由可在其中找到。 FRBA 负责人 Robert Floyd 博士和 AI 部门的 Judith James 博士将指导该新员工。 Kenneth Hensley 博士将担任初级导师。 Hensley 博士已在我们的教员中工作了五年，拥有 R01 等级，并且是我们被引用次数最多的年轻研究人员之一。指导委员会相信他已经准备好担任这一角色。我们还将聘请 Rheal Towner 博士和 Mark Coggeshall 博士（该应用的细胞信号核心负责人）的专业知识。 2) 免疫生物学和癌症项目的补充：Paul Kincade 博士领导 OMRF 的免疫生物学和癌症项目。过去七年里他招募的两名新兵，博士。马克·科格歇尔 (Mark Coggeshall) 和孙晓红 (Xiao Hong Sun) 是我们过去十年中最优秀的员工之一。两者均已成功将其实验室转入 OMRF，均已成功地在国家层面上争夺资金（其中有 6 个 R01），并且均已晋升为正式成员。这个五人项目（与韦伯博士和汤普森博士一起）值得再增加一名同事。他们在招聘核心部分概述了他们选择的逻辑以及他们将招聘的人员。事实上，这项搜寻工作正在顺利进行。根据招聘情况，该受训者将受到该杰出教师中任何成员的指导。金卡德博士很可能将担任高级导师，孙博士将担任初级导师。 3) 分子、细胞和发育生物学研究项目的补充：一年前，OMRF 聘请 Gary Gorbsky 博士作为 MCDB 的新负责人。他正在为他的项目招募新教师。早期招募的主要重点将是增强我们在发育生物学方面的实力，特别是因为我们拥有运转良好的世界一流的小鼠设施。我们得到了长老会健康基金会的支持，帮助招募以遗传学为重点的个人，并寻求 COBRE 的支持，招募一名对发育生物学感兴趣的教员，特别是一位能够与我们杰出的心血管研究项目、关节炎的成员合作的教员和免疫学研究计划，或神经科学研究计划。此次招聘符合 COBRE 的新准则，该准则允许在 COBRE 的主要主题之外进行招聘。我们将确保该新员工得到良好的指导，并且新员工将可以完全使用我们的核心设施。这将提供一个正式的机制，将该招聘纳入 COBRE 流程。显然，我们将向指导委员会、我们的外部咨询委员会以及 NCRR 寻求指导。 4) 免疫生物学和癌症项目以及分子细胞和发育生物学研究项目的联合任命：此次招聘的目标是邀请某人来到我们的校园，将我们两个最好的项目的研究兴趣联系起来：IC和MCDB。在这里，我们寻求确定某人（例如）对正在发育的小鼠免疫系统进行基因操作进行研究，可能是在 B 细胞或 T 细胞方面，因为我们在 B 和 T 细胞发育方面有很深入的研究，但不是在基因水平上。这样的人可以轻松地适应这两个项目，并充当它们之间互动的渠道。博士。金卡德和戈尔布斯基已同意进行此次联合招募。 5) 自由基生物学和衰老项目的补充：我们寻求资金来填补 OMRF 的一个主要空白：数学建模师（重点是神经生物学）。 Jose Conchello 博士是我们分子细胞和发育生物学项目成像小组的数学家，他的加入对我们整个研究所产生了影响，我们寻求资金将这种水平的数学专业知识扩展到神经生物学。担任此职位的个人将与 OMRF 和 OUHSC 现有的一组经验丰富的神经科学研究人员合作。我们相信这项强大的技术需要出现在我们的校园中并纳入 FRBA 计划中。更多详细信息包含在其中。指导这样的人会很复杂，因为我们 OMRF 没有类似的人才，但是计算机建模领域国际公认的研究员托马斯·雷 (Thomas Ray) 博士就位于俄克拉荷马大学诺曼校区附近。俄克拉荷马州。 Conchello 博士以及博士。弗洛伊德和唐应该提供我们所需的高级指导。如果需要，我们将定期从州外派人来这里为新兵提供指导。