RECRUITING CORE

招聘核心人员

• 批准号: 7381146
• 负责人: J Donald Capra
• 金额: $ 29.7万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381146
• 关键词: RECRUITING; CORE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The selection of the five recruiting packages for this application was an exacting and laborious process. Each of the program heads made a half-day presentation to the steering committee of the present COBRE grant. Drs. Tang, Floyd, Harley, Gorbsky and Kincade argued for a position in their programs. After institutional resources, space and direction was approved, descriptions of the recruits were solicited. We endeavored to recruit scientists jointly whenever possible, as illustrated by the Neuroimmunologist being recruited by the Programs in FRBA/A&I, and the Molecular Biologist being recruited by the Programs in MCDB/I&C (see Recruiting Core, this application). Such joint recruits act to integrate research in individual Programs, serving as conduits between them. Integration of this kind strengthens the researcher by placing him/her in dual research environments, the Programs involved, and the institution as a whole. Importantly, this integration plays a vital role in allowing us to assemble diverse teams of researchers to target complex goals, as illustrated by our emerging Neuroscience Initiative and recent successful U19 award. In each instance, we have provided within the application the justification for the recruit, who will mentor the recruit, and the exact plans for the recruit within our organizational framework. We have also taken heed of the current guidelines that allow at least some allocation of resources to others in an institution not directly connected to the narrow focus of the COBRE program under review. As such, following with our long-range strategic plan to add to our faculty in neuroscience and cell, molecular and developmental biology, we are using four of the recruiting packages to support those efforts. 1) Joint Appointment for a Neuro-immunologist in Free Radical Biology and Aging Program and the Arthritis and Immunology Research Program: OMRF has an outstanding program in Free Radical Biology and Aging. The current six members of the program focus effort on the neuroinflammation that accompanies Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS). We believe expanding this program by four investigators will bring us to a critical mass in this arena. OMRF also has an outstanding program in Arthritis and Immunology (Drs. James, Harley, Reichlin, Farris, Centola, etc). We have determined that a joint recruit between these two programs would benefit both, and foster communication between two of our highly successful research efforts. The two Programs have determined that such a recruit should be a neuro-immunologist, and it is to support this recruit that we are requesting funds. The full justification for the recruit is found within. Dr. Robert Floyd, head of FRBA, and Dr. Judith James of AI will mentor this recruit. Dr. Kenneth Hensley will serve as junior mentor. Dr. Hensley has been on our faculty for five years, has an R01, and is one of our most cited young investigators. The Steering Committee believes he is ready for this role. We will also enlist the expertise of Dr. Rheal Towner and Dr. Mark Coggeshall (head of the Cell Signaling Core on this application). 2) Addition to the Immunobiology and Cancer Program: Dr. Paul Kincade heads OMRF's Immunobiology and Cancer program. His two recruits over the last seven years, Drs. Mark Coggeshall and Xiao Hong Sun, are among the best additions to our staff in the last decade. Both have successfully transitioned their laboratories to OMRF, both have successfully competed on a national level for funds (six R01s between them), and both have been promoted to full member status. The five-person program (with Drs. Webb and Thompson) deserves an additional colleague. They have outlined in the section on recruiting cores the logic for their choices and the people they will be recruiting. Indeed, this search is well under way. Depending on the recruit, this mentee will be mentored by any member of this distinguished faculty. Likely, Dr. Kincade will take the senior mentorship role and Dr. Sun a junior mentor role. 3) Addition to the Molecular, Cell and Developmental Biology Research Program: A year ago, OMRF recruited Dr. Gary Gorbsky as the new head of MCDB. He is in the process of recruiting new faculty for his program. The major emphasis of the early recruiting will be to add to our strength in developmental biology, especially as we have a world class mouse facility that is functioning well. We have support from the Presbyterian Health Foundation to help recruit individuals with an emphasis in genetics, and seek support from this COBRE to recruit a faculty member with a developmental biology interest, especially one who would collaborate with members of our outstanding Cardiovascular Research Program, Arthritis and Immunology Research Program, or Neuroscience Research Initiative. This recruit falls under the new guidelines for the COBRE that allow recruiting outside the major theme of the COBRE. We will be certain that this recruit is well mentored, and the recruit will have full access to our Core Facilities. This will provide a formal mechanism to include this recruit in the COBRE process. Obviously, the Steering Committee, our External Advisory Committee as well as NCRR will be approached for guidance. 4) Joint appointment to the Immunobiology and Cancer Program and the Molecular Cell and Developmental Biology Research Program: The goal of this recruitment would be to bring someone to our campus who will bridge the research interests of two of our finest programs: IC and MCDB. Here we seek to identify someone who (for example) performs studies employing genetic manipulation of the developing immune system of the mouse, perhaps on the B cell or the T cell side, as we have great depth in B and T cell development, but not at the genetic level. Such a person would fit comfortably in both programs and serve as a conduit for interaction between them. Drs. Kincade and Gorbsky have agreed to undertake this joint recruitment. 5) Addition to the Free Radical Biology and Aging Program: We seek funds to fill a major void at OMRF: a mathematical modeler (with an emphasis in neurobiology). The addition of Dr. Jose Conchello, a mathematician in our imaging group in our Molecular Cell and Developmental Biology Program has impacted our entire Institute, and we seek funds to extend this level of mathematical expertise into neurobiology. The individual who assumes this position will be collaborating with a group of experienced neuroscience researchers already in place at OMRF and OUHSC. We believe this powerful technology needs to be present on our campus and located in the FRBA program. More details are enclosed within. Mentoring someone like this will be complex, as we have no comparable talent at OMRF, however Dr. Thomas Ray, an internationally recognized researcher in the field of computer modeling is located nearby at the University of Oklahoma Norman Campus. Oklahoma. Dr. Conchello as well as Drs. Floyd and Tang should provide the senior level of mentorship we need. If needed we will bring someone here from outside the state on a regular basis to provide mentoring for the recruit.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。为此应用程序选择五个招聘包是一个严格而费力的过程。每个计划负责人都向现任柯布雷赠款的指导委员会进行了半天的演讲。博士。唐，弗洛伊德，哈雷，戈尔斯基和金凯德主张他们的计划中的职位。经过机构资源，空间和方向的批准后，对新兵的描述进行了征求。我们努力尽可能地共同招募科学家，如FRBA/A＆I计划所招募的神经免疫学家所示，以及MCDB/I＆C中的计划招募的分子生物学家（请参阅招聘核心，本应用程序）。这种联合新兵法案旨在整合单个计划中的研究，并作为他们之间的管道。这种整合通过将研究人员置于双重研究环境，所涉及的计划以及整个机构中，从而增强了研究人员。重要的是，这种整合在允许我们组建各种研究人员的团队以针对复杂目标的方面起着至关重要的作用，如我们新兴的神经科学计划和最近成功的U19奖所示。 在每种情况下，我们都在应用程序中提供了新兵的理由，谁将指导新兵，以及在我们的组织框架内的招聘计划的确切计划。 我们还关注了当前的准则，这些准则至少允许向其他机构中的其他资源分配，而不是直接与正在审查的毛cre计划的狭窄重点相关的机构。因此，遵循我们的远程战略计划，以增加神经科学和细胞的教职员工，分子和发育生物学，我们将使用四个招聘包来支持这些努力。 1）自由基生物学和衰老计划以及关节炎与免疫学研究计划的神经免疫学家联合任命：OMRF具有自由基生物学和衰老方面的出色计划。该计划的六名成员将重点放在帕金森氏病，阿尔茨海默氏病和肌萎缩性侧面硬化症（ALS）伴随的神经炎症上。我们认为，扩大四名调查人员的计划将使我们在这个领域的关键群众。 OMRF还拥有关节炎和免疫学方面的出色计划（James，Harley，Reichlin，Farris，Centola等）。我们已经确定，这两个计划之间的共同招募将受益，并在我们两项非常成功的研究工作之间促进沟通。这两个计划已经确定，这种新兵应该是神经免疫学家，这是为了支持我们要求资金的新兵。在内部找到了新兵的全部理由。 FRBA负责人Robert Floyd博士和AI的Judith James博士将指导这位新兵。肯尼斯·亨斯利（Kenneth Hensley）博士将担任初级导师。 Hensley博士在我们的教职员工任职五年，拥有R01，并且是我们引用最多的年轻调查员之一。指导委员会认为他已经准备好担任这一角色。我们还将获得Rheal Towner博士和Mark Coggeshall博士的专业知识（该应用程序的细胞信号核心负责人）。 2）补充免疫生物学和癌症计划：Paul Kincade博士负责OMRF的免疫生物学和癌症计划。在过去的七年中，他的两名新兵博士。 Mark Coggeshall和Xiao Hong Sun是过去十年来我们员工的最佳补充之一。两者都成功地将实验室过渡到OMRF，都成功地在国家一级争夺了资金（他们之间的六个R01），并且两者都被提升为正式的成员身份。五人计划（与韦伯博士和汤普森博士）值得一位同事。他们在招募核心的部分中概述了他们的选择逻辑和将要招募的人。确实，这种搜索正在进行中。根据新兵的不同，该受训者将由该杰出教师的任何成员进行指导。 Kincade博士可能会担任高级指导职位，Sun博士成为初级导师的角色。 3）补充分子，细胞和发育生物学研究计划：一年前，OMRF招募了Gary Gorbsky博士为MCDB的新负责人。他正在为自己的计划招募新教师。早期招聘的主要重点是增加我们在发育生物学方面的力量，尤其是当我们拥有一个正常运作的世界一流小鼠设施时。我们得到了长老会健康基金会的支持，以帮助招募重点是遗传学的人，并寻求该皮的支持，以招募具有发育生物学兴趣的教职员工，尤其是一个将与我们杰出的心血管研究计划，关节炎和免疫学研究计划或神经科学研究的一项合作的人合作。这项新兵属于鞋底的新准则，该准则允许在毛绒的主要主题之外招募。我们可以肯定的是，这一新兵受到了良好的指导，并且新兵将完全访问我们的核心设施。这将提供一种正式的机制，可以将此新兵纳入鞋底过程。显然，将向指导委员会，我们的外部咨询委员会以及NCRR寻求指导。 4）联合任命免疫生物学和癌症计划以及分子细胞和发育生物学研究计划：这项招聘的目的是将某人带到我们校园，他们将弥合我们两个最好的计划的研究兴趣：IC和MCDB。在这里，我们试图确定某人（例如）（例如）使用对小鼠发展的免疫系统进行遗传操纵的研究，也许是在B细胞或T细胞侧，因为我们在B和T细胞的发展中具有很高的深度，但在遗传水平上却没有。这样的人可以舒适地适合两个程序，并作为他们之间互动的渠道。博士。 Kincade和Gorbsky已同意进行这项联合招聘。 5）补充自由基生物学和衰老计划：我们寻求资金来填补OMRF的主要空隙：数学建模者（重点是神经生物学）。在我们的分子细胞和发育生物学计划中的成像组中的数学家何塞·康切洛（Jose Conchello）博士的增加影响了整个研究所，我们寻求资金将这种数学专业水平扩展到神经生物学中。假设这一职位的个人将与OMRF和OUHSC的一群经验丰富的神经科学研究人员合作。我们认为，这种强大的技术需要在我们的校园中存在，并位于FRBA计划中。更多详细信息包含在其中。指导像这样的人将很复杂，因为我们在OMRF没有可比的才能，但是计算机建模领域的国际认可的研究人员托马斯·雷博士位于俄克拉荷马大学诺曼大学校园附近。俄克拉荷马州。 Conchello博士和博士。弗洛伊德（Floyd）和唐（Tang）应提供我们需要的高级指导水平。如果需要，我们会定期将某人带到国家外部，为新兵提供指导。