Core A--Administration and Biostatistics Core

核心A--行政和生物统计核心

• 批准号: 7218018
• 负责人: CARLOS M FERRARIO
• 金额: $ 16.69万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7218018
• 关键词: biomedical facility; experimental designs; statistics /biometry

The biostatistics core's primary objective is to collaborate with investigators in each individual study throughout all phases of their research. We will provide support or be responsible for methodological, statistical and computer related issues including study design, sample size calculation and power analysis, randomization schedules, data collection instruments, data storage and retrieval, data analysis and manuscript preparation. The biostatistics core will be responsible for ensuring that each study design is adequate, including a clear definition of primary and secondary outcomes for each study, according to the hypothesis stated by the principal investigator's sample. There is assistance with sample size determination with specified Type I and Type II errors, provision of alternative methods to test hypothesis when the initial approach is not feasible relative to the pool of animals available and development of randomization schedules or sampling schemes for each study. The Core helps implement quality control measures common to all studies and provides methodological support to each project in developing new analytical techniques as needed and assisting in data analysis and interpretation of results as needed.

生物统计学核心的主要目标是在其研究的所有阶段中与研究人员合作。我们将为方法论，统计和计算机相关的问题提供支持或负责，包括研究设计，样本量计算和功率分析，随机时间表，数据收集工具，数据存储和检索，数据分析和手稿准备。根据首席研究者样本的假设，生物统计学核心将负责确保每个研究设计都足够，包括对每项研究的主要和次要结果的明确定义。在样本量确定的情况下，有指定的I型和II型误差，当初始方法相对于可用动物库不可行，并为每项研究的随机时间表或抽样方案的开发提供替代方法来检验假设。核心有助于实施所有研究共有的质量控制措施，并为每个项目提供根据需要开发新的分析技术的方法学支持，并根据需要进行数据分析和结果解释。