Integrated PhD Training Program in Cancer Biology

癌症生物学综合博士培训计划

• 批准号: 7220759
• 负责人: KENNETH J MARIANS
• 金额: $ 25.84万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7220759
• 关键词: NIH Roadmap Initiative tag; clinical research; curriculum; educational resource design /development; health science profession; information dissemination; mentoring /mentor; neoplasm /cancer; neoplasm /cancer pharmacology; neoplasm /cancer therapy; postgraduate education; science education; training

DESCRIPTION (From the application): The goal of the new Cancer Biology Graduate Program at the Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, is to increase the pace of translation of laboratory findings to clinical practice by introducing a new curriculum in cancer biology aimed at providing Ph.D. researchers with both the basic science training they need to be successful bench scientists and with a strong clinical perspective that includes:, connecting the biology of cancer to its clinical presentation, the challenges of clinical treatment, the workings of patient-oriented research, the process of development of Pharmaceuticals, and an understanding of how human physiology influences mode of intervention. The program accomplishes this with a unique integrated didactic curriculum designed by a team of basic and physician scientists that includes: (i) the Cancer Biology Core Course, which transits from a primarily basic science orientation to a more physiology-based orientation, culminating in "disease modules" that reach back to the basic science sections to explore in depth the underpinnings of the natural history, biology, current treatments, and existing model systems; (ii) bench science thesis research; and (iii) a thesis project-related apprenticeship with a Clinical Mentor, who serves as the student's guide to hospital-based academic activities. The faculty of the Gerstner Sloan-Kettering Graduate School are drawn from both the basic science and clinical arms of the Cancer Center.

描述（来自申请）：纪念斯隆-凯特琳癌症中心路易斯·V·格斯特纳生物医学科学研究生院新的癌症生物学研究生项目的目标是加快实验室研究结果转化为临床的步伐通过引入旨在提供博士学位的新癌症生物学课程来进行实践。研究人员既受过成为成功的实验科学家所需的基础科学培训，又具有强大的临床视角，包括：将癌症生物学与其临床表现联系起来、临床治疗的挑战、以患者为中心的研究工作、过程药物开发的发展，以及对人类生理学如何影响干预模式的理解。该计划通过由基础科学家和医学科学家团队设计的独特的综合教学课程来实现这一目标，其中包括：（i）癌症生物学核心课程，从主要的基础科学方向转变为更加基于生理学的方向，最终“疾病模块”，回到基础科学部分，深入探索自然历史、生物学、当前治疗方法和现有模型系统的基础； (ii) 基础科学论文研究； (iii) 与临床导师一起进行与论文项目相关的学徒期，临床导师将担任学生在医院开展学术活动的指南。格斯特纳·斯隆-凯特琳研究生院的教职人员来自癌症中心的基础科学和临床部门。