Very Low-Cost C-Scan Ultrasonic Imaging

成本极低的 C 扫描超声波成像

• 批准号: 7159451
• 负责人: Karen E Morgan
• 金额: $ 59万
• 依托单位: POCKETSONICS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-03-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7159451
• 关键词: clinical research; experience; fasting; fluid; nurses; oncology; quality of life; satisfaction; skin; ultrasonography; ultrasound

DESCRIPTION (provided by applicant): The goal of this program is to save lives and improve the quality of care of people requiring vascular access by enabling quicker access and minimizing failed attempts. Direct visualization of target vessels with ultrasound imaging will minimize number of attempts and failed attempts, thus allowing more rapid vascular access for administration of IV fluids or medications, improving patient satisfaction, reducing the need for more invasive procedures and saving healthcare providers' valuable time. This program will make ultrasound guided vascular access available to a greater number of healthcare providers in a wide range of settings by developing and validating a low-cost ($2,000 per unit), easy to use, and highly portable ultrasonic imaging system called the Sonic Window. This system will be comparable in size to a mobile phone or PDA and is specifically designed to meet the needs of users with little or no experience in medical imaging at a fraction of the cost of currently available portable ultrasound systems. Our system will form C-Scan images (image plane parallel to skin surface) that are intuitive for novice users and display those images at the site of acquisition, allowing the user to see the image in the perspective that would be obtained if you had a clear 'window' through the skin into the tissue or vessel of interest. The Sonic Window is being realized by combining a low profile 2D array, custom integrated circuits, novel beamforming and image processing algorithms implemented on a commercial Digital Signal Processor, and a LCD display. Innovative technological approaches are employed to circumvent conventional engineering wisdom that holds that C-Scan imaging is inherently more complex and costly than B-Scan imaging (plane perpendicular to skin surface). The Specific Aim of this Phase II research is to demonstrate the efficacy of a prototype Sonic Window system for guiding peripheral IV access procedures. This aim will be accomplished through 2 clinical studies involving nurses which compare the success of ultrasound guided peripheral IV insertions with the prototype to landmark based peripheral IV insertions (control). The first study will be comprised of known difficult to access patients (i.e. 1 failed access attempt) requiring IV placement. The second study will be comprised of patients requiring IV placement from a nursing unit with a population of patients generally regarded to have difficult access (e.g. bariatrics, oncology, ICU). In order to perform the studies, we will first complete integration of a clinical Sonic Window prototype and perform system validation, optimization and safety verification. A positive conclusion from this research, demonstrating faster and easier peripheral IV access, will increase confidence in the commercial viability of the Sonic Window product. In future stages of development, we will extend this work to include more complicated access procedures such as central line insertions. This research is a collaborative effort between PocketSonics, Inc. and the University of Virginia (Departments of Biomedical Eng., Electrical and Computer Eng. and the School of Nursing). The goal of this program is to save lives and improve the quality of care of people requiring vascular access by enabling quicker access and minimizing failed attempts. Direct visualization of target vessels with ultrasound imaging will minimize number of attempts and failed attempts, thus allowing more rapid vascular access for administration of IV fluids or medications, improving patient satisfaction, reducing the need for more invasive procedures and saving healthcare providers valuable time. This program will make ultrasound guided vascular access available to a greater number of healthcare providers in a wide range of settings by developing a low-cost ($2,000 per unit), easy to use, and highly portable ultrasonic imaging system called the Sonic Window.

描述（由申请人提供）：该计划的目的是挽救生命并提高需要血管通道的人们的护理质量，从而可以更快地访问并最大程度地减少失败的尝试。具有超声成像的目标血管的直接可视化将最大程度地减少尝试的数量和失败的尝试，从而使静脉输液或药物的施用更快，从而提高患者满意度，减少对更多侵入性手术的需求并节省医疗保健提供者的宝贵时间。该程序将通过开发和验证低成本（每单位$ 2,000），易于使用和高度便携式超声超声成像系统，在广泛的环境中提供超声引导的血管通道，称为声音窗口。该系统的尺寸将与手机或PDA相当，并且专门设计用于满足用户的需求，这些用户很少或根本没有医学成像经验，而当前可用的便携式超声系统的成本很少。我们的系统将形成对新手用户直观的C扫描图像（平行于皮肤表面的图像平面），并在获取站点上显示这些图像，从而使用户可以在视角上查看图像，如果您有一个将“窗户”通过皮肤清除到感兴趣的组织或容器中。通过组合低调的2D阵列，自定义集成电路，新颖的光束成形和图像处理算法，可以实现声音窗口，并实现了Sonic窗口。使用创新的技术方法来规避传统的工程智慧，该智慧认为，与B扫描成像（垂直于皮肤表面的平面）相比，C扫描成像本质上更为复杂和昂贵。该II期研究的具体目的是证明原型声音窗口系统用于指导外围静脉输入程序的功效。这一目标将通过2项涉及护士的临床研究来实现，这些临床研究将超声引导的周围静脉内静脉内插入与原型的成功与基于里程碑的外围静脉静脉内插入（对照）进行了比较。第一项研究将由已知难以访问患者（即1次失败尝试）组成，需要放置静脉注射。第二项研究将包括需要从通常被认为很难进入患者的护理单位的静脉注射的患者（例如，减肥症，肿瘤学，ICU）。为了进行研究，我们将首先完成临床声音窗口原型的整合，并执行系统验证，优化和安全验证。这项研究的积极结论表明，更快，更容易的外围静脉输入将增加对声音窗户产品的商业可行性的信心。在未来的开发阶段，我们将扩展这项工作，以包括更复杂的访问程序，例如中央线插入。这项研究是Pocketsonics，Inc。与弗吉尼亚大学（生物医学工程学系，电气和计算机工程学系和护理学院）之间的合作努力。该计划的目的是挽救生命并提高需要血管通行的人们的护理质量，从而可以更快地访问并最大程度地减少失败的尝试。具有超声成像的目标血管的直接可视化将最大程度地减少尝试的数量和失败的尝试，从而使静脉输液或药物的管理更快地通道，提高患者满意度，减少对更多侵入性手术的需求并节省医疗保健提供者的宝贵时间。该程序将通过开发低成本（每单位$ 2,000），易于使用和高度便携式的超声超声成像系统（称为Sonic窗口），在广泛的设置中提供超声引导的血管通道。