Preventing Postpartum Depression in Adolescent Mothers

预防青春期母亲的产后抑郁症

• 批准号: 7128620
• 负责人: MAUREEN G PHIPPS
• 金额: $ 18.75万
• 依托单位: WOMEN AND INFANTS HOSPITAL-RHODE ISLAND
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7128620
• 关键词: adolescence (12-20); age at pregnancy; audiotape; behavioral /social science research tag; clinical research; clinical trials; female; focus groups; handbook; human subject; human therapy evaluation; interview; longitudinal human study; low socioeconomic status; medically underserved population; parents; patient oriented research; postpartum depression; prenatal care; psychological stressor; psychotherapy; questionnaires; racial /ethnic difference; role; social support network; therapy design /development; videotape /videodisc

DESCRIPTION (provided by applicant): The consequences of adolescent childbearing include significant social and health impacts on the parenting teens and their children. Each year, more than 400,000 births in the United States are to mothers less than 20 years old. Pregnant teenagers are at increased risk for adverse birth outcomes and parenting difficulties. Depression during the postpartum period transforms an already challenging process into a potentially overwhelming one. This hardship may be a major determinant of poor outcomes for these young mothers and their children. Clearly, the prevention of postpartum depression with this vulnerable population should be an integral part of prenatal care and of special interest to health care providers and policy makers. Unfortunately, virtually no research has examined the effects of a preventive intervention to reduce postpartum depression in pregnant teenagers. The objective of this treatment development grant is to develop a psychosocial intervention for financially disadvantaged, pregnant adolescents and to collect preliminary data on the efficacy of this intervention in reducing the degree of postpartum depression. The intervention is primarily an interpersonally-oriented intervention that targets those factors that may play a significant role in the development of postpartum depression in adolescent mothers (i.e., poor social support, role transitions, and life stressors). The specific aims of this project are to: (SA1) Develop the intervention program, including refining the intervention manual to reflect the needs of our target population, and developing adherence and competence scales, therapist training procedures, and research procedures for recruitment and retention of subjects; (SA2) Conduct a randomized controlled pilot study to evaluate the initial efficacy of the proposed intervention compared to a didactic control condition in a sample of 100 pregnant adolescents and to provide an estimate of effect size in comparison to the control condition; and, (SA3) Evaluate the pilot study results and procedures to inform the refinement of the intervention and procedures to prepare for a larger clinical trial evaluating the efficacy of this intervention. Findings from this study will have important implications for preventing significant morbidity in adolescent mothers and their children.

描述（由申请人提供）：青少年生育的后果包括对养育青少年及其子女的重大社会和健康影响。在美国，每年有超过 40 万例新生儿是由 20 岁以下的母亲生育的。怀孕的青少年发生不良分娩结果和育儿困难的风险增加。产后抑郁症将本来就充满挑战的过程变成了一个潜在的压倒性过程。这种困难可能是这些年轻母亲及其孩子结局不佳的一个主要决定因素。显然，预防这一弱势群体的产后抑郁症应该成为产前护理的一个组成部分，并且引起医疗保健提供者和政策制定者的特别关注。不幸的是，几乎没有研究检验预防性干预措施对减少怀孕青少年产后抑郁症的效果。这项治疗开发赠款的目的是为经济困难的怀孕青少年制定心理社会干预措施，并收集有关该干预措施在降低产后抑郁程度方面的功效的初步数据。该干预措施主要是一种以人际为导向的干预措施，针对那些可能在青少年母亲产后抑郁症的发展中发挥重要作用的因素（即不良的社会支持、角色转换和生活压力源）。该项目的具体目标是： (SA1) 制定干预计划，包括完善干预手册以反映目标人群的需求，并制定依从性和能力量表、治疗师培训程序以及招募和保留治疗师的研究程序。科目； (SA2) 开展一项随机对照试点研究，以 100 名怀孕青少年为样本，评估所提议干预措施与教学对照条件相比的初步效果，并提供与对照条件相比效果大小的估计； (SA3) 评估试点研究结果和程序，为干预措施和程序的完善提供信息，为评估该干预措施有效性的更大规模临床试验做好准备。这项研究的结果将对预防青少年母亲及其子女的严重发病具有重要意义。