CORE--BIOSTATISTICS

核心--生物统计学

• 批准号: 6989957
• 负责人: DANIEL J. SARGENT
• 金额: $ 37.52万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-15 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6989957
• 关键词: biomedical facility; clinical trials; computer data analysis; data management; health science research support; human population study; mathematics; neoplasm /cancer; oncology; statistical service /center; statistics /biometry

The Biostatistics Shared Resource of the Mayo Clinic Cancer Center (MCCC) has provided expert statistical collaboration with MCCC investigators for over 30 years. The purpose of the resource is to provide statistical and biomathematical collaboration for the development and conduct of peer-reviewed cancer research generated by investigators in the MCCC. This research ranges from the bench to the bedside to the population, and encompasses basic science, clinical trials, epidemiologic research, and other translational and educational research. The primary usage of the funds provided to the resource by the CCSG is to support statistical and mathematical collaboration on pilot projects, for assistance to investigators in developing approved research projects not otherwise funded but leading towards external funding, and to support unanticipated needs for statistical collaboration on MCCC approved projects. Over the 30 year history of the Biostatistics Shared Resource, the group has undergone a natural and deliberate evolution and expansion, spurred by the expanding research activities of the MCCC. The Biostatistics Shared Resource has multiple focus areas (teams) tied together into a well-organized, efficient core. These are: (I) a Clinical Trials team responsible for cancer clinical trials, associated translational research, interventional psychosocial research, and imaging, together with patient and public education research projects, (II) a Population Science team responsible for providing statistical collaboration and data management support for cancer observational studies, including genetic and molecular epidemiology, (III) a Quality of Life team responsible for providing general and specific advice, measurement tools, and analysis for MCCC investigators who are investigating the impact of clinical and psychosocial interventions on cancer patients, families, caregivers, and others, and (IV) a Biomathematics team that provides collaborative expertise in the mathematical aspects of imaging, data processing and analysis, mathematical modeling (e.g. of tumor growth), and general mathematical or algorithmic issues. These groups work efficiently and effectively together to provide statistical and biomathematical collaboration to Mayo Clinic Cancer Center investigators across all three MCCC campuses.

30 多年来，梅奥诊所癌症中心 (MCCC) 的生物统计共享资源一直与 MCCC 研究人员提供专家统计合作。该资源的目的是为 MCCC 研究人员进行同行评审的癌症研究的开发和开展提供统计和生物数学合作。这项研究的范围从实验室到临床再到人群，涵盖基础科学、临床试验、流行病学研究以及其他转化和教育研究。 CCSG 提供给该资源的资金的主要用途是支持试点项目的统计和数学合作，协助研究人员开发未经其他资助但导致外部资助的批准研究项目。 资金，并支持 MCCC 批准项目的统计合作的意外需求。在生物统计共享资源 30 年的历史中，在 MCCC 不断扩大的研究活动的推动下，该小组经历了自然而刻意的演变和扩张。 生物统计共享资源有多个重点领域（团队），它们结合在一起形成一个组织良好、高效的核心。它们是：(I) 临床试验团队，负责癌症临床试验、相关转化研究、介入心理社会研究和成像，以及患者和公共教育研究项目，(II) 人口科学团队，负责提供统计协作和数据对癌症观察研究的管理支持，包括遗传和分子流行病学，(III) 生活质量团队，负责为正在调查临床和心理社会干预对癌症患者影响的 MCCC 研究人员提供一般和具体建议、测量工具和分析、家庭、护理人员和其他人，以及 (IV) 一个生物数学团队 提供成像、数据处理和分析、数学建模（例如肿瘤生长）以及一般数学或算法问题的数学方面的协作专业知识。这些小组高效、有效地合作，为 MCCC 所有三个校区的 Mayo Clinic 癌症中心研究人员提供统计和生物数学协作。