Perfectionism in adolescents with depression

抑郁症青少年的完美主义

• 批准号: 7113523
• 负责人: RACHEL H JACOBS
• 金额: $ 3.94万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7113523
• 关键词: adolescence (12-20); antidepressants; attitude; behavioral /social science research tag; child psychology; clinical trials; cognitive behavior therapy; combination therapy; disease /disorder proneness /risk; fluoxetine; human subject; human therapy evaluation; longitudinal human study; major depression; mental disorder chemotherapy; mental health epidemiology; patient oriented research; placebos; predoctoral investigator; psychopharmacology; relapse /recurrence; serotonin inhibitor; suicide

DESCRIPTION (provided by applicant): The Treatment for Adolescents with Depression Study (TADS) is a randomized controlled trial funded by the National Institute of Mental Health and conducted at 14 sites. A sample of 439 adolescents between 12 and 17 years of age with a diagnosis of major depressive disorder participated in TADS. Participants were randomly assigned to 1 of 4 treatments: cognitive behavior therapy (CBT), fluoxetine (FIX), cognitive behavior therapy in combination with fluoxetine (Combo), or pill placebo (PBO). In addition to primary outcome measures, several additional measures were included in the TADS dataset and will be available for secondary analyses. My research will look at the role of dysfunctional attitudes in the development of adolescent depression. Specifically, I will explore perfectionism as a possible predictor, moderator, and/or mediator of treatment response in terms of depression symptoms and suicidality. Longitudinal data will be available in approximately 1 year and will allow for the testing of models of relations between perfectionism, dysfunctional attitudes, and depression. These findings will contribute to the understanding of cognitive vulnerability for depression and mechanisms of treatment response in depressed adolescents.

描述（由申请人提供）：青少年抑郁症治疗研究 (TADS) 是一项由美国国家心理健康研究所资助并在 14 个地点进行的随机对照试验。 439 名 12 至 17 岁之间被诊断患有重度抑郁症的青少年样本参与了 TADS。参与者被随机分配接受 4 种治疗中的一种：认知行为疗法 (CBT)、氟西汀 (FIX)、认知行为疗法联合氟西汀 (Combo) 或安慰剂安慰剂 (PBO)。除了主要结果指标外，TADS 数据集中还包含一些其他指标，可用于二次分析。我的研究将探讨功能失调的态度在青少年抑郁症发展中的作用。具体来说，我将探讨完美主义作为抑郁症状和自杀倾向治疗反应的可能预测因素、调节因素和/或中介因素。纵向数据将在大约一年内提供，并将允许测试完美主义、功能失调的态度和抑郁之间的关系模型。这些发现将有助于了解抑郁症的认知脆弱性以及抑郁症青少年的治疗反应机制。