Motivation, Self-Monitoring, & Family Process in Autism

动机、自我监控、

• 批准号: 7031533
• 负责人: PETER C MUNDY
• 金额: $ 31.33万
• 依托单位: UNIVERSITY OF MIAMI CORAL GABLES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-03-15 至 2010-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7031533
• 关键词: adolescence (12-20); anxiety; autism; awareness; behavioral /social science research tag; biomarker; clinical research; comorbidity; electroencephalography; electrophysiology; emotions; evoked potentials; executive function; family structure /dynamics; human subject; middle childhood (6-11); motivation; neurobiology; parents; self concept; social behavior; social behavior disorders; socializations

DESCRIPTION (provided by applicant): This application describes an interrelated program of studies that will provide a broad and multifaceted array of data on neurobiological and family processes that contribute to the social development of higher-function children with autism (UFA children). It has been designed to provide descriptive scientific data necessary to establish an immediately useful foundation for the development of more effective diagnostic and intervention methods to meet the specific social emotional needs of higher functioning children in the elementary through high-school years. In conjunction with this applied goal, this program of studies has also been designed to test new hypotheses about the role of motivation and self-monitoring related brain systems, as well as family factors, in the social development of HFA children. In particular, this application describes research that will examine dimensions of neurobiological and family processes that theory suggests contribute to both social impairments and comorbidity in higher functioning children. Included here are: 1) motivation processes associated with anterior EEG asymmetry, 2) self-monitoring processes associated with EEG error related negativity and, 3) processes associated with parent's emotional status and family critical expressed emotion (EE). 1 aim of this research is to replicate and extend preliminary observations that anterior EEG asymmetry measures provide an important marker of subgroups of HFA children that significantly differ from each other, and controls, on measures of social impairment, comorbid anxiety and executive functions. A second aim is to test the hypotheses that HFA children will differ from controls on measures of self-monitoring, and that self-monitoring will be related to HFA sub-group differences in social impairments and comorbid anxiety. A final aim of this application is to examine the degree to which parent emotional status and/or family expressed emotion is related to individual differences in social impairments and comorbidity among HFA children. To address these specific aims this application proposes a study of 120 HFA children in 2 age groups (8-12 and 13-17 years) and 120 age, gender and IQ matched controls.

描述（由申请人提供）：本申请描述了一项相互关联的研究计划，该计划将提供有关神经生物学和家庭过程的广泛而多方面的数据，这些数据有助于自闭症儿童（UFA儿童）的社会发展。它旨在提供必要的描述性科学数据，以建立一个有用的基础，以开发更有效的诊断和干预方法，以满足基础上高中生在高中年度中较高功能的儿童的特定社会情感需求。结合了这个应用目标，该研究计划还旨在测试有关动机和自我监测相关的大脑系统以及家庭因素在HFA儿童社会发展中的作用的新假设。特别是，该应用程序描述了将研究神经生物学和家庭过程的维度的研究，理论提出，这些过程提出了较高功能较高的儿童的社会障碍和合并症。这里包括：1）与前脑电图不对称相关的动机过程，2）与EEG错误相关的消极性相关的自我监控过程，以及3）与父母的情绪状况和家庭关键表达的情绪相关的过程（EE）。 1这项研究的目的是复制和扩展初步观察，即前脑外不对称度量为HFA儿童的亚组提供了重要的标志，这些标志是彼此之间显着差异的，以及对社会障碍，合并焦虑和执行功能的措施的控制。第二个目的是检验HFA儿童将与自我监控措施的控制不同的假设，并且自我监控将与HFA子组在社会障碍和合并焦虑方面的差异有关。该应用的最终目的是检查父母的情感状况和/或家庭表达的情绪与HFA儿童的社会障碍和合并症的个体差异有关的程度。为了解决这些特定目的，该申请提出了对2个年龄组（8-12和13-17岁）和120岁，性别和智商匹配的控制的120名HFA儿童的研究。