Kettering Lab Renovation to enhance PHS-supported environmental health research

凯特林实验室改造以加强 PHS 支持的环境健康研究

• 批准号: 7839524
• 负责人: Shuk-Mei Ho
• 金额: $ 481.95万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-07 至 2015-01-06
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7839524
• 关键词: Age; American; Area; Bioinformatics; Biometry; Caliber; Capital; Carbon; Communities; Computer Simulation; Consumption; Discipline; Disease susceptibility; Employment; Environment; Environmental Health; Epidemiology; Epigenetic Process; Faculty; Floor; Funding; Heart Atrium; Home environment; Housing; Human Resources; Interdisciplinary Study; Kentucky; Life; Link; Maintenance; Mentors; Occupational Health; Ohio; Performance; Phase; Population; Positioning Attribute; Recovery; Recruitment Activity; Research; Research Training; Scientist; Time; Toxicology; Training Programs; Translating; Universities; Wing; Work; base; community based participatory research; comparative; graduate student; human disease; improved; meetings; operation; public health relevance; repaired; research facility; square foot

DESCRIPTION (provided by applicant): The Department of Environmental Health at the University of Cincinnati is a world leader in environmental and occupational health, with over $22M in external research in 2008. The building that houses this department is showing its age, with one wing already beyond repair. This project will renovate the 3rd floor Kehoe wing and Atrium space of Kettering Lab, to improve research facilities, and meet the following specific aims: 1. Contribute to the American Recovery and Reinvestment Act of 2009 with a "shovel ready" renovation project, which will establish the equivalent of full-time employment for 30 new construction-related positions each year of the project duration-estimated at 24 months. Completion of this work will expand our research capacity to accommodate up to twelve (12) new faculty positions and 60 - 80 support personnel, beyond the construction phase. 2. Renovate the of the 3rd floor Kehoe wing of Kettering Lab (8,910 gross square feet), and transform the under-utilized atrium into useful interdisciplinary research space (4,355 gross square feet), which will meet the physical needs of modern, trans-disciplinary research, with optimization of energy performance, improve energy efficiency, maintenance, and operations to extend the life of Kettering Lab for several decades. 3. Provide a research and training platform as a basis for Comparative Effective Research based on our successful mentoring and training programs, with a focus on epigenetic contributions to human disease. 4. Increase our ability to recruit exemplary scientists to the Ohio-Kentucky region by increasing our allure-to new faculty, staff, postdocs and graduate students. 5. Develop a physical home for transdisciplinary research in a yet-to-be-established Center for Epigenetic Epidemiology, which will house expertise in basic toxicology, computational modeling, bioinformatics, epidemiology, biostatistics, and community based participatory research. This team will focus on understanding how epigenetics links the environment to disease susceptibility in populations, translate research findings to the community, and increase scientific capital. PUBLIC HEALTH RELEVANCE (provided by applicant): The UC Department of Environmental Health is requesting funds to renovate and transform our research space from outdated facilities to modern areas that will bring together scientists from different disciplines. This will increase cooperation among our scientists, help us recruit high-caliber people to the Ohio- Kentucky region, and create an area where we can connect scientists with the community. These improvements will also reduce energy consumption and our carbon footprint.

描述（由申请人提供）：辛辛那提大学环境卫生系是环境和职业卫生的世界领导者，2008年在外部研究中超过2200万美元。该部门的建筑物正在显示其年龄，其中一个机翼已经无法修复。该项目将翻新Kettering Lab的三楼Kehoe机翼和中庭空间，以改善研究设施，并符合以下特定目标： 1。通过一个“铲子就绪”翻新项目为2009年的《美国恢复与再投资法》做出了贡献，该项目将在每年24个月的项目期限内每年建立相当于30个与新建筑有关的职位的全职工作。这项工作的完成将扩大我们的研究能力，以容纳十二（12）个新的教师职位和60-80个支持人员，超出了建筑阶段。 2. Renovate the of the 3rd floor Kehoe wing of Kettering Lab (8,910 gross square feet), and transform the under-utilized atrium into useful interdisciplinary research space (4,355 gross square feet), which will meet the physical needs of modern, trans-disciplinary research, with optimization of energy performance, improve energy efficiency, maintenance, and operations to extend the life of Kettering Lab for several decades. 3.提供研究和培训平台，作为基于我们成功的指导和培训计划的比较有效研究的基础，重点是对人类疾病的表观遗传学贡献。 4。通过增加我们对新的教职员工，员工，博士后和研究生，提高我们将典范科学家招募到俄亥俄州肯塔基州地区的能力。 5。在尚未建立的表观遗传流行病学中心中开发跨学科研究的物理住所，该研究将容纳基本毒理学，计算建模，生物信息学，流行病学，生物统计学和社区参与性研究方面的专业知识。该团队将专注于了解表观遗传学如何将环境与人群中的疾病敏感性联系起来，将研究结果转化为社区并增加科学资本。 公共卫生相关性（由申请人提供）：UC环境卫生部要求资金翻新和将我们的研究空间从过时的设施转变为现代领域，这些设施将使来自不同学科的科学家聚集在一起。这将增加我们的科学家之间的合作，帮助我们招募高质量人员到俄亥俄州地区，并创建一个可以将科学家与社区联系起来的领域。这些改进还将减少能耗和我们的碳足迹。