Sorting of the IGF-II Receptor in Polarized Cells

极化细胞中 IGF-II 受体的分选

• 批准号: 6780855
• 负责人: Nancy M. Dahms
• 金额: $ 18.75万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-05-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6780855
• 关键词: apical membrane; basolateral membrane; binding proteins; carbohydrate receptor; cell differentiation; cellular polarity; gastrointestinal epithelium; growth factor receptors; insulinlike growth factor; intracellular transport; laboratory rat; lysosomes; mannose 6 phosphate; membrane activity; phosphorylation; protein transport; receptor binding; receptor expression; site directed mutagenesis; tissue /cell culture; transfection

项目成果

Basolateral sorting signal of the 300-kDa mannose 6-phosphate receptor.

300-kDa 甘露糖 6-磷酸受体的基底外侧分选信号。

• DOI: 10.1152/ajpgi.00028.2001
• 发表时间: 2002
• 期刊: American journal of physiology. Gastrointestinal and liver physiology
• 作者: Wick,DebraA;Seetharam,Bellur;Dahms,NancyM
• 通讯作者: Dahms,NancyM

Expression of insulin-like growth factor (IGF)-I receptors, IGF-II/cation-independent mannose 6-phosphate receptors (CI-MPRs), and cation-dependent MPRs in polarized human intestinal Caco-2 cells.

极化人肠道 Caco-2 细胞中胰岛素样生长因子 (IGF)-I 受体、IGF-II/阳离子非依赖性甘露糖 6-磷酸受体 (CI-MPR) 和阳离子依赖性 MPR 的表达。

• DOI: 10.1016/0005-2736(95)00234-0
• 发表时间: 1996
• 期刊: Biochimica et biophysica acta
• 作者: Dahms,NM;Seetharam,B;Wick,DA
• 通讯作者: Wick,DA

Expression of IGF-II and IGF binding proteins in differentiating human intestinal Caco-2 cells.

IGF-II 和 IGF 结合蛋白在分化人肠道 Caco-2 细胞中的表达。

• DOI: 10.1152/ajpendo.1995.269.5.e804
• 发表时间: 1995
• 期刊: The American journal of physiology
• 作者: Zhang,Y;Wick,DA;Seetharam,B;Dahms,NM
• 通讯作者: Dahms,NM

Biosynthesis and secretion of the mannose 6-phosphate receptor and its ligands in polarized Caco-2 cells.

• DOI: 10.1152/ajpgi.1999.277.3.g506
• 发表时间: 1999-09
• 期刊: American journal of physiology. Gastrointestinal and liver physiology
• 作者: D. A. Wick;B. Seetharam;N. Dahms

Regulation of lysosomal and ubiquitin degradative pathways in differentiating human intestinal Caco-2 cells.

分化人肠道 Caco-2 细胞中溶酶体和泛素降解途径的调节。

• DOI: 10.1016/0167-4889(95)00027-p
• 发表时间: 1995
• 期刊: Biochimica et biophysica acta
• 作者: Zhang,Y;Wick,DA;Haas,AL;Seetharam,B;Dahms,NM
• 通讯作者: Dahms,NM