RESEARCH TRAINING IN TRANSLATIONAL TUMOR IMMUNOLOGY

转化肿瘤免疫学研究培训

• 批准号: 6874548
• 负责人: ALFRED E CHANG
• 金额: $ 25.98万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6874548
• 关键词: RESEARCH; TRAINING; TRANSLATIONAL; TUMOR; IMMUNOLOGY; RESEARCH; TRAINING; TRANSLATIONAL; TUMOR; IMMUNOLOGY

DESCRIPTION (Applicant's Description): This application represents a new proposal for an NCI-sponsored program of "Research Training in Translational Tumor Immunology" at the University of Michigan. Faculty preceptors with interests in translational immunology have been selected from their primary D e p artments of Surgery, Medicine, Microbiology, Chemistry, Pathology, Radiation Oncology, and Laboratory Animal Medicine. These preceptors are also members of the new Graduate Program in Immunology and/or the Comprehensive Cancer Center's (CCC's) Tumor Immunology Program. Each of the 17 investiga- tors directs an active laboratory with a record of securing extramural support. Dr. James J. Mule will serve as the Program Director, and he will work closely with a Steering Committee to select trainees and formulate program policy. Predoctoral trainees will be enrolled in the Graduate Program in Immunology, which combines the resources of the Medical School, Graduate School, and CCC. The students will take courses in biochemistry, genetics, and immunology to prepare them for dissertation research with any of the preceptors. Postdoctoral trainees will devote their effort to full-time research. The proposed training program, through the Graduate Program in Immunology and the Tumor Immunology Program, will co-sponsor four major activities: a) a biweekly journal club at which trainees and preceptors meet for guided explorations of recent immunology papers; b) a monthly seminar series at which invited speakers from other universities, research institutes, and industry present research data and spend a day meeting with trainees and faculty; c) a Research Colloquium course, whose topic and instructor varies each semester; it allows graduate students (and postdoctoral auditors) to read about, and discuss in depth, a series of important topics in modern basic and translational immunology; and d) a scientific retreat held quarterly by the Tumor Immunology Program, at which faculty members present topic-related research data and collaborative efforts are established. Graduate students and postdoctoral fellows attend these retreats also. The program includes plans for training in research responsibility and for recruitment of underrepresented minority groups. Support is requested for four predoctoral and four postdoctoral trainees each year. Predoctoral and postdoctoral trainees should leave the program well prepared for academic careers focused on translational aspects of immunologic research as it pertains to the development of new strategies for the treatment of cancer.

描述（申请人的描述）：此申请代表一个新的 NCI赞助计划的“翻译研究培训”计划 密歇根大学的肿瘤免疫学。 对转化免疫学的兴趣是从其主要的 D E P手术，医学，微生物学，化学，病理学， 辐射肿瘤学和实验室动物医学。 这些受体也是 免疫学新研究生课程和/或综合研究生课程的成员 癌症中心（CCC）的肿瘤免疫学计划。 17个调查中的每一个 TOR指导一个活跃的实验室，并具有确保壁外的记录 支持。 James J. Mule博士将担任该计划主任，他将 与指导委员会紧密合作，以选择受训者并配制 计划政策。 托管前学员将入学研究生课程 在结合医学院资源的免疫学上 学校和CCC。 学生将参加生物化学，遗传学， 和免疫学，以准备与任何一个 受体。 博士后学员将致力于全职 研究。 拟议的培训计划，通过研究生课程 免疫学和肿瘤免疫学计划将共同赞助四个主要 活动：a）每两周的期刊俱乐部，在该俱乐部会议 为了探索最近的免疫学论文； b）每月研讨会 系列邀请了其他大学，研究机构的演讲者， 行业介绍研究数据，并与受训者和 学院; c）研究座谈会课程，其主题和讲师各不相同 每个学期；它允许研究生（和博士后审核员）阅读 关于现代基础和 翻译免疫学； d）由 肿瘤免疫学计划，教职员工与主题有关 建立了研究数据和协作工作。 研究生 博士后研究员也参加了这些务虚会。 该程序包括 研究责任培训的计划和招募 代表性不足的少数群体。 请求四个冠军的支持 每年有四名博士后学员。 杂物和博士后 学员应为专注于学术职业做好准备 关于免疫研究的翻译方面，因为它与 制定癌症治疗的新策略。