Midcareer Development in Nonpharmacologic Analgesia

非药物镇痛的职业中期发展

• 批准号: 6711790
• 负责人: ELVIRA Valentina LANG-ANDERSON
• 金额: $ 13.15万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6711790
• 关键词: alternative medicine; analgesia; anxiety; biopsy; blood pressure; breast neoplasm /cancer diagnosis; breast surgery; career; clinical research; cognition; cortisol; female; heart rate; human subject; hypnosis; information dissemination; mind control; pain; patient oriented research; physiologic stressor; psychological stressor; questionnaires; relaxation; saliva

Alternative medical methods enjoy broad acceptance by the public, but are rarely integrated into conventional medical practice. In the largest prospective randomized study of its kind, published by the Lancet, the candidate showed that non-pharmacologic analgesia in the form of self- hypnotic relaxation during invasive medical procedures significantly reduces patients' pain anxiety, drug use, number of complications, hemodynamic instability, and procedure time. This results in substantial resource savings. The immediate goal of the candidate is to expand and validate this concept of integrated alternative/conventional health care delivery across disciplines. The long-term goal is the successful transition from scientific investigation to general implementation of acute non-pharmacologic analgesia in clinical settings. The candidate is uniquely situated to achieve the state goals: A strong foundation in laboratory and clinical research as well as her position as Director of International Radiology provides her the necessary credibility to promote and implement mind body intervention during invasive medical procedures. Her acceptance by both conventional medical and mind-body oriented professional societies permit integration of her methods into both communities. The candidate's RO1 and DOD funding focuses on assessment on non-pharmacologic analgesia during invasive vascular procedures and during large core breast biopsy. Under the proposed mid-career award, she will (1) acquire authoritative expertise in the introduction and quality assessment of non- pharmacologic analgesia techniques in conventional clinical settings (2) assume a key role in the newly established Harvard-wide Division for Research and Education and Complementary and Integrative Medical Therapies, and (3) mentor the next generation of researchers and practitioners in this field. Towards these aims the candidate will acquire additional research skills in educational technology, quality assessment, and web-based dissemination; acquire expertise in additional complementary and alternative therapies; and will make available to other researchers data banks, ideas, experience and patients in fully monitored clinical environment. She will assume primary mentoring responsibility for a total of 15 beginning clinical researchers. Upon completion, the candidate will have established herself as an authority in the introduction and quality assessment of combined alternative/conventional medical practices. The mentoring of beginning clinical researchers will have contributed towards fostering a self- sustaining mode of integrated practice in the future.

替代医学方法享有公众的广泛接受，但很少融入常规医学实践中。在由柳叶刀出版的最大的同类前瞻性随机研究中，候选人表明，在侵入性医疗程序中以自我催眠放松形式的非药物镇痛大大减少了患者的疼痛焦虑，药物使用，并发症，并发症的数量，血液动力学不稳定和程序时间。这可以节省大量资源。候选人的直接目标是扩大和验证跨学科的综合替代/常规卫生保健提供的概念。长期目标是从科学研究中成功过渡到临床环境中急性非药物镇痛的一般实施。候选人在实现国家目标方面具有独特的位置：实验室和临床研究的强大基础以及她作为国际放射学总监的地位为她提供了在入侵性医疗程序中促进和实施身体干预的必要信誉。她对常规医学和以心身为导向的专业社会的接受允许将她的方法整合到两个社区中。候选人的RO1和DOD资金集中在侵入性血管手术期间和大型核心乳房活检期间对非药物镇痛的评估。根据拟议的中期奖，她将（1）在传统临床环境中对非药理镇痛技术的引入和质量评估中获得权威专业知识（2）在新成立的哈佛大学研究，教育和互补和互补和综合医疗疗法的新成立的部门中扮演关键角色，以及下一代研究人员和研究员，该领域的研究员和实践者和实践者。为了这些目标，候选人将获得教育技术，质量评估和基于Web的传播方面的其他研究技能；获得其他补充和替代疗法的专业知识；并将向其他受监测的临床环境中的其他研究人员提供数据库，想法，经验和患者。她将对总共15名初学者研究人员承担主要的指导责任。完成后，候选人将在对替代/常规医疗实践的介绍和质量评估中确立自己的权威。开始临床研究人员的指导将有助于促进将来的自动维持综合实践模式。