CORE--CLINICAL

核心--临床

• 批准号: 6410533
• 负责人: CRAIG R WEINERT
• 金额: $ 24.55万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-12-01 至 2001-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6410533
• 关键词: adult respiratory distress syndrome; biomedical facility; data collection; data management; human subject; lung injury; patient /disease registry

The objective of the Clinical Core is to facilitate the transfer of clinical data and specimens to the Project Directors' laboratories and to speed the application of basic science discoveries to critically ill patients with acute lung injury. The SCOR Acute Lung Injury Database which is currently enrolling 70 patients per year will continue as a comprehensive of clinical information on the etiology, management and long-term outcome of patients with lung injury. The Database will also link patients' clinical information with tissue specimens obtained through Core B protocols and examined in SCOR investigators' laboratories. As promising new therapies for lung injury are ready to be tested on patient populations, then the clinical core's expertise in human subjects protection and consent procedures; patient recruitment and follow-up; and standardized data collection will permit rapid assessment of clinical efficacy.

临床核心的目标是促进转移 向项目主管实验室提供临床数据和样本 加速基础科学发现在危重疾病中的应用 急性肺损伤患者。 SCOR 急性肺损伤数据库 目前每年招募 70 名患者，并将继续作为 有关病因、治疗和治疗的全面临床信息 肺损伤患者的长期结果。数据库还将 将患者的临床信息与通过以下方式获得的组织标本联系起来 核心 B 协议并在 SCOR 研究人员实验室进行检查。作为 有前途的肺损伤新疗法已准备好在患者身上进行测试 人群，然后是临床核心在人类受试者方面的专业知识 保护和同意程序；患者招募和随访；和 标准化数据收集将允许快速评估临床 功效。