MONITOR HEART RATE IN MONKEYS W/NON INJURIOUS SELF DIRECTED BITINGNG

通过非伤害性自我定向咬合监测猴子的心率

• 批准号: 6591355
• 负责人: MELINDA NOVAK
• 金额: $ 11.11万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6591355
• 关键词: Mammalia; behavioral /social science research tag; carbohydrates; mental disorders; nervous system; psychology

The disorder of self-injurious behavior in monkeys is characterized with occasional bouts of wounding and frequent episodes of non-injurious biting Little is known about the functions of such behavior in rhesus monkeys; however, this disorder may persist because of some reinforcing quality such as tension reduction Evidence from human populations with this disorder (e g , prisoners who engage in cutting) provide strong support for this view To examine the tension reduction hypothesis in monkeys, we analyzed heart rate activity during episodes of non-injurious, self-directed biting (NIB) The subjects were 7 monkeys involved in heart rate testing that were observed to bite themselves (NIB) during the test The monkeys were fitted with vests containing radiotelemetry units in the afternoon and monitored for heart rate the next morning The monkeys were simultaneously videotaped to record their behavior Heart rate was analyzed in 30-second epochs We evaluat ed heart r ate in intervals prior to, during, and just after a biting episode and compared these values to the baseline heart rate Heart rate was significantly elevated during biting episodes compared to the intervals prior to and after biting Heart rate had already begun to increase in the interval prior to biting as indicated by a significant elevation compared to baseline Immediately after biting, heart rate dropped precipitously to baseline levels as would be expected according to the tension-reduction hypothesis To rule out simple locomotor explanations of the changes in heart rate, we examined a similar activity (biting the vest) and performed the same heart rate analysis Vest biting was associated with a modest, nonsignificant increase in heart rate with little change in heart rate in the following interval These results suggest that NIB can produce tension reduction which is independent of simple locomotor changes Further research will be aimed at examining stress hormone le vels in monkeys just prior to and after biting as an independent corroboration of the tension reduction hypothesis

猴子的自我伤害行为的障碍是 以偶尔的伤害和频繁发作为特征 关于这种功能，无妇人的咬人知之甚少 恒河猴的行为；但是，这种疾病可能会持续存在，因为 一些加强质量的质量，例如减少张力证据 这种疾病的人群（E G，参与的囚犯 切割）为这种观点提供了强有力的支持以检查紧张局势 减少猴子的假设，我们分析了心率活性 在非妇女，自我指导的咬人（NIB）的情节中 受试者是参与心率测试的7只猴子 在测试期间观察到自己（Nib）是 下午装有装有Radiotelemetry单元的背心， 第二天早晨，猴子是心率的监测 同时被录像以记录其行为心率是 在30秒的时期分析我们的心脏间隔 在叮咬剧集之前，之中和之后进行了比较 基线心率心率的值显着 与之前的间隔相比 咬人后，心率已经开始增加 在咬咬之前，如明显的高程所示 咬人后立即基线，心率急剧下降到 基线水平是根据 减少张力假设，排除简单的运动解释 在心率的变化中，我们检查了类似的活动（咬人 背心）并进行相同的心率分析效果是 与适度的，无显着增加心率相关的与 在以下间隔中，心率几乎没有变化 表明NIB可以减少张力，而与 简单的运动变化进一步研究将旨在检查 在咬人之前和之后，猴子的压力激素是 张力减少假设的独立佐证