Exploring the emergence of psychotic experiences using multimodal neuroimaging and mathematical modelling

使用多模式神经影像和数学建模探索精神病经历的出现

• 批准号: 2119709
• 金额: --
• 依托单位: CARDIFF UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2119709
• 关键词: Exploring; emergence; psychotic; experiences; using

The overall aim is to understand the computational and neurocognitive processes underlying the emergence of psychosis, and neurocognitive contributions to psychopathological risk. Psychotic disorders such as schizophrenia are among the most devastating mental health conditions and leading contributors to the global burden of disease. Psychotic symptoms involve a loss of contact with reality in the form delusions (false beliefs) and hallucinations (perceptual experiences in the absence of stimuli). Given the complexity of the processes underlying these symptoms, recent advances have often been driven by integrated, cross-disciplinary approaches using mathematical models, behavioural testing, and neuroimaging (1).

总体目的是了解精神病出现的基础的计算和神经认知过程以及对精神病理学风险的神经认知贡献。精神分裂症（例如精神分裂症）是最具毁灭性的心理健康状况之一，也是造成全球疾病负担的主要贡献者。精神病症状涉及与现实的失去与现实的接触形式（错误的信念）和幻觉（在没有刺激的情况下的感知经历）。考虑到这些症状基础的过程的复杂性，最近进步通常是由使用数学模型，行为测试和神经影像学的综合，跨学科方法驱动的（1）。