Quasi-monochromatic X-ray Source for Mammography

用于乳腺X线摄影的准单色X射线源

• 批准号: 6669658
• 负责人: Melvin Arthur Piestrup
• 金额: $ 38.35万
• 依托单位: ADELPHI TECHNOLOGY, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2006-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6669658
• 关键词: X ray; beta radiation; bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; diagnosis design /evaluation; energy source; image enhancement; mammography; particle accelerators; particle beam; radiation dosage

Description (provided by applicant): The objective of the proposed research is to construct a prototype narrow-bandwidth x-ray source for mammography using a thin, efficient hybrid radiator driven by a relativistic electron beam of moderate energy and current. The high x-ray yield (photons/electron) of the source permits the use of modest electron-beam currents, preventing thermal damage to the radiator itself. The radiator is thin, permitting the electron beam to pass through it many times, thereby proportionally increasing the emitted x-ray flux. Since the source is inherently collimated and quasi-monochromatic, it will produce higher quality radiographic images while lowering the dose to the patient. Phase I experiments have demonstrated intense quasi-monochromatic x-rays in the range optimum for mammography (15 to 25 keV). Calculations of the x-ray yield and the average current passing through the radiator have demonstrated that there is adequate flux for imaging. The research will proceed by improving the design of the thin hybrid radiator and experimentally demonstrating its feasibility by producing images of inanimate phantoms. The potential for successful development of the prototype imaging system is very high because our Phase I research has already experimentally demonstrated, both electron recycling and narrow bandwidth, tunable x-ray generation. These results indicate that a high quality mammogram can be generated in less than 3 seconds.

描述（由申请人提供）：拟议研究的目标是 使用 由相对论电子束驱动的薄型高效混合散热器 中等能量和电流。高 X 射线产量（光子/电子） 源允许使用适度的电子束电流，防止热 损坏散热器本身。散热器很薄，允许电子 光束多次穿过它，从而按比例增加 发射的 X 射线通量。由于光源本质上是准直的并且 准单色，它将产生更高质量的射线照相图像，同时 降低患者的剂量。第一阶段的实验已经证明了强烈的 准单色 X 射线，处于乳房 X 光检查最佳范围（15 至 25 keV）。 X射线产额和通过的平均电流的计算 散热器已证明有足够的通量用于成像。这 研究将通过改进薄型混合散热器的设计来进行 通过生成无生命的图像来实验证明其可行性 幻影。成功开发原型成像的潜力 系统非常高，因为我们一期研究已经通过实验 证明了电子回收和窄带宽、可调谐 X 射线 一代。这些结果表明高质量的乳房X光检查可以 生成时间不到 3 秒。