DOUBLE BLIND GCSF TO PRETERM NEUTROPENIA NEONATES

双盲 GCSF 治疗早产中性粒细胞减少症新生儿

• 批准号: 6304920
• 负责人: KURT R SCHIBLER
• 金额: $ 0.16万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2001-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6304920
• 关键词: blood disorder chemotherapy; blood toxicology; clinical research; colitis; colony stimulating factor; drug screening /evaluation; granulocytopenia; human subject; human therapy evaluation; immunotherapy; neutrophil; newborn human (0-6 weeks); pediatric pharmacology; placebos; pregnancy toxemia /hypertension; premature infant human; blood disorder chemotherapy; blood toxicology; clinical research; colitis; colony stimulating factor; drug screening /evaluation; granulocytopenia; human subject; human therapy evaluation; immunotherapy; neutrophil; newborn human (0-6 weeks); pediatric pharmacology; placebos; pregnancy toxemia /hypertension; premature infant human

Many premature newborn infants have difficulty manufacturing a sufficient number of white blood cells to protect them from infection. This results in a high incidence of infectious complications mary: affecting premature newborns in newborn intensive care units. This study was designed to determine if a factor that stimulates the bone marrow to make more white blood cells (granulocyte colony-stimulating factor or G-CSF) could be effective in raising the white blood cell count of premature neonates, and thereby protecting them from infectious disorders.

许多过早的新生婴儿难以生产足够数量的白细胞来保护他们免受感染。这导致了玛丽的感染并发症的高发：影响新生儿重症监护病房的早产新生儿。 这项研究旨在确定刺激骨髓以使更多的白细胞（颗粒细胞菌落刺激因子或G-CSF）的因素有效地提高过早新生儿的白细胞计数，从而保护它们免受感染性疾病的侵害。