UK-Further development of droplet microfluidic based chemical sensors for rapid measurement of nutrients in water

英国-进一步开发基于液滴微流体的化学传感器，用于快速测量水中的营养物质

基本信息

批准号：
NE/S013458/1
负责人：
Xize Niu
金额：
$ 15.91万
依托单位：
University of Southampton
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2019
资助国家：
英国
起止时间：
2019 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=NE%2FS013458%2F1
关键词：
UK Further development droplet microfluidic

项目摘要

Traditionally chemicals in the aquatic environment (e.g. nitrate, phosphate) are measured by manual collection and laboratory analysis of discrete water samples. Microfluidic sensors offer an attractive alternative: by taking and analysing samples autonomously in the environment, they remove the need for manual sampling and allow real-time monitoring of water composition and quality.The current state-of-the-art sensors are not widespread due to a range of issues, most notably complicated fluidic control and their inefficient use of chemical reagent. This increases the size of the sensor and its power consumption, limits the frequency that measurements can be taken and duration the sensor can be deployed each time.Droplet microfluidics (in which nanolitre water samples are taken and subsequently operated on as droplets within an immiscible oil) is a novel microfluidic method that, in addition to other advantages, crucially offers higher analytical throughput and much more efficient use of consumables (reagent consumption being orders of magnitude lower). We have previously developed and demonstrated the first-ever droplet microfluidic sensor prototype for measuring nitrate and nitrite that uses drastically lower reagent consumption relative to the current state of the art. In this project we will mature the technology and demonstrate it in real-world operation in partnership with end users, including a UK public body and Chinese water company. These demonstrations will help us to refine the sensor, demonstrate its effectiveness, and ready it for commercial exploitation.

传统上，水生环境中的化学物质（例如硝酸盐，磷酸盐）是通过对离散水样品的手动收集和实验室分析来测量的。微流体传感器提供了一种有吸引力的替代方法：通过在环境中自动进行样品，它们消除了对手动采样的需求，并允许对水成分和质量进行实时监控。当前的最新传感器并不广泛，这是由于一系列问题而广泛的，最明显的问题，最明显的是复杂的液体控制及其对化学探测器的无效使用。这增加了传感器的大小及其功耗，限制了可以进行测量的频率，并且可以每次都可以部署传感器的持续时间。DROPLET微流体（其中采集纳米列列列型水样品，然后随后在不可能的用途中进行了更高的较高的用途，并且在其他较高的用途中可以通过较高的方法进行了较高的绘制方法，并提供了更多的较高的层次，而不是其他较高的层次，而不是其他较高的层次。（试剂消耗是低数量级）。我们以前已经开发并证明了有史以来第一个液滴微流体传感器原型，用于测量相对于当前技术状态的硝酸盐和亚硝酸盐的测量硝酸盐和亚硝酸盐的原型。在这个项目中，我们将与最终用户（包括英国公共机构和中国水公司）合作，将技术成熟，并在现实世界中进行演示。这些演示将有助于我们完善传感器，证明其有效性，并为商业剥削做好准备。