The ecology of evolution: the role of environmental heterogeneity in evolutionary dynamics.

进化生态学：环境异质性在进化动力学中的作用。

基本信息

批准号：
NE/G004390/1
负责人：
Tim Coulson
金额：
$ 7.47万
依托单位：
Imperial College London
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2010
资助国家：
英国
起止时间：
2010 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=NE%2FG004390%2F1
关键词：
ecology evolution role environmental heterogeneity

项目摘要

Although we have a good general understanding of how evolution operates, we have only limited insight into its detailed workings in natural populations. A prominent challenge is to understand the extent to which variation in environmental conditions affects evolutionary change within natural populations. Improved knowledge in this area will greatly advance our understanding of how genetic diversity is maintained in natural populations and of how populations are likely to respond to predicted changes in climate. The characteristics of individuals in a population are a consequence of their genes, the environment in which they live and the evolution that has occurred up to that point. So much is clear, but this simple statement conceals much complexity. Specifically, the consequences of carrying particular genes can vary with environmental conditions; it is possible (but not generally proven) that organisms express more of their genetic potential under good rather than bad environmental conditions. Similarly, the strength of natural selection, whereby some individuals have higher survival or reproductive success than others, may vary with environmental conditions. Since evolutionary change occurs when natural selection acts on inherited characters, environmental fluctuations can therefore have a substantial impact on evolution. Finally, because some of the genes underlying a particular character (e.g. body size) may be the same as, or associated with, the genes underlying another character (e.g. parasite resistance), characters are not free to evolve independently of one another. Instead the effect of natural selection on one character will be constrained by any selection that is also occurring on other characters to which it is genetically tied. Recent research suggests that these constraints also vary with environmental conditions. Currently, we have very little understanding of how these various processes interact to shape evolution in natural populations. In this study we will investigate the effect of environmental conditions on evolutionary processes using data from an unmanaged study population of Soay sheep on the island of St Kilda, NW Scotland. The data set is particularly useful for this study because, firstly, we have records on the individual life histories of several thousand sheep measured across 23 years. DNA profiling has been used to determine paternity and provide a family tree suitable for the kind of genetic analyses proposed here. Secondly, our previous research has demonstrated that there are four kinds environmental variation which show strong temporal variation affecting sheep performance, and we will be investigating all four kinds of variation in this study: the weather, sheep population density, food availability and parasite abundance. We will address the effect of the environmental conditions described above on the expression of genetic variation, the strength of natural selection and the genetic relationships between characters. Specifically we will ask how the environmental affects first, the expression of genetic variation in single characters like body weight: is more genetic variation always expressed when conditions are good? Second does environmental variation affect genetic relationships between characters? For example, are body size and parasite resistance freer to evolve separately under good or bad conditions? Third, is selection stronger or weaker under good environmental conditions? Together these analyses will allow us to predict the course of evolution under specific time series of environmental conditions - for example systematic climate change. Long-term studies of individually-recognised wild animals such as these are an important source of information on many aspects of ecology and evolutionary biology, and the proposed grant would guarantee continuity of data collection for one of the UK's most valuable ecological and evolutionary field data sets.

尽管我们对进化的运作方式有很好的总体了解，但我们对其在自然群体中的详细运作方式了解有限。一个突出的挑战是了解环境条件的变化在多大程度上影响自然种群内的进化变化。提高这一领域的知识将极大地增进我们对自然种群中如何维持遗传多样性以及种群如何应对预测的气候变化的理解。种群中个体的特征是其基因、生存环境以及迄今为止发生的进化的结果。事情已经很清楚了，但是这个简单的陈述掩盖了很多复杂性。具体来说，携带特定基因的后果可能会因环境条件而异。有可能（但尚未普遍证明）生物体在良好的环境条件下而不是恶劣的环境条件下表现出更多的遗传潜力。同样，自然选择的强度（即某些个体比其他个体具有更高的生存或繁殖成功率）可能会随环境条件而变化。由于当自然选择作用于遗传特征时就会发生进化变化，因此环境波动会对进化产生重大影响。最后，由于某一特定特征（例如体型）的某些基因可能与另一特征（例如寄生虫抗性）的基因相同或相关，因此特征不能自由地彼此独立地进化。相反，自然选择对一个角色的影响将受到在与其基因相关的其他角色上也发生的任何选择的限制。最近的研究表明，这些限制也随着环境条件的变化而变化。目前，我们对这些不同过程如何相互作用以塑造自然种群的进化知之甚少。在这项研究中，我们将使用来自苏格兰西北部圣基尔达岛上不受管理的索伊羊研究群体的数据来调查环境条件对进化过程的影响。该数据集对于本研究特别有用，因为首先，我们记录了 23 年中数千只羊的个体生活史。 DNA 分析已用于确定亲子关系并提供适合此处提出的遗传分析类型的家谱。其次，我们之前的研究表明，有四种环境变化表现出强烈的时间变化影响羊的生产性能，我们将在本研究中调查所有四种变化：天气、羊群密度、食物供应和寄生虫丰度。我们将讨论上述环境条件对遗传变异表达、自然选择强度以及性状之间遗传关系的影响。具体来说，我们首先会问环境如何影响体重等单一性状的遗传变异的表达：当条件好的时候，是否总是会表达更多的遗传变异？其次，环境变化是否会影响性状之间的遗传关系？例如，在良好或恶劣的条件下，身体大小和寄生虫抗性是否更自由地分别进化？第三，在良好的环境条件下，选择是更强还是更弱？这些分析将使我们能够预测特定时间序列的环境条件下的进化过程——例如系统性气候变化。对此类单独认可的野生动物的长期研究是生态学和进化生物学许多方面的重要信息来源，拟议的拨款将保证英国最有价值的生态和进化现场数据之一的数据收集的连续性套。