Exotic isotope production for medical applications

用于医疗应用的奇异同位素生产

• 批准号: MR/X036561/1
• 负责人: Thomas Day Goodacre
• 金额: $ 201.25万
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FX036561%2F1
• 关键词: Exotic; isotope; production; medical; applications

Radioactive isotopes have ratio of protons and neutrons that results in their instability. This presents both a plethora of opportunities, and a challenge to obtain them due to their finite nature. This work seeks to meet the rising medical demand for these exotic isotopes, through the development of new technologies and approaches for radioactive isotope production and separation. While the use of established medical isotopes is growing, there are challenges to the supply as nuclear research reactors are decommissioned across the world. Additionally, the application of non-standard isotopes such as 225Ac have shown significant promise for the treatment of cancers, while others have applications in medical imaging. Reliable processes for the production and separation of these isotopes are required to realise the full potential of these applications and to produce pre-clinical amounts for initial studies. This work seeks to address this through ion source and electromagnetic mass separator development for exotic medical isotope production.

放射性同位素具有质子和中子的比率，从而导致其不稳定性。这既提出了很多机会，也提出了由于其有限的性质而获得的挑战。这项工作旨在通过开发新技术和放射性同位素生产和分离来满足这些异国同位素的医疗需求不断上升。尽管既定的医疗同位素的使用正在增长，但由于核研究反应堆在世界各地已退役，因此供应面临挑战。此外，非标准同位素（例如225AC）的应用对癌症的治疗显示了很大的希望，而其他同位素则在医学成像中应用。这些同位素的生产和分离的可靠过程必须实现这些应用的全部潜力，并产生临床前数量以进行初步研究。这项工作旨在通过离子源和电磁质量分离器开发来解决这一问题，以产生外来医学同位素生产。