SPECIAL RURAL POPULATIONS

特殊农村人口

• 批准号: 3790450
• 负责人: ROBERT B WALLACE
• 金额: --
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3790450
• 关键词: Native Americans; blood chemistry; blood glucose; cognition; cognition disorders; depression; frail elderly; glucose tolerance test; human middle age (35-64); human old age (65+); human subject; hypertension; interview; medical records; noninsulin dependent diabetes mellitus; questionnaires; rural area; socioeconomics; statistics /biometry

The long-term goal of this research is to investigate the reasons for lack of compliance with medical regimens in a rural Native American population with a high incidence of type II diabetes mellitus, so that diabetes- associated morbidity and mortality may be decreased. To address that issue, this pilot study will compare the cognitive function of two groups of older rural Native Americans: those with and without type II diabetes mellitus, to determine whether type II diabetes is associated with decreased cognitive function. In people isolated from health care, cognitive dysfunction may lead to an inability to follow treatment plans, maintain self-care, and determine appropriately when to seek health care, all of which may lead to poorer outcomes. The specific aims are (1) to develop and administer a tool to assess cognitive function in an older population of Native Americans, and (2) to determine if type II diabetes mellitus is related to a diminished level of cognitive function. Participants, community-dwelling elders aged 45 to 74 years, will be identified for each group from one reservation within the Aberdeen Area of the Indian Health Service in South Dakota. They will be interviewed to obtain measures of psychobehavioral function; information about demographic and socioeconomic variables, other risk factors for cognitive alteration, and diabetes history (in the diabetic group); and hematologic measures of glucose control. Medical record review will be conducted to validate this data and to obtain additional information about the history of chronic illnesses and conditions and recent physiological parameters. Comparisons between and within the two groups will be made using correlation, multiple regression analysis, multivariate analysis of variance, and analysis of covariance techniques.

这项研究的长期目标是调查缺乏的原因 在美国土著人口中遵守医疗方案 II型糖尿病的发生率很高，因此糖尿病 - 相关的发病率和死亡率可能会降低。 解决这个问题 问题，该试点研究将比较两组的认知功能 较老的美国原住民：患有和没有II型糖尿病的人 Mellitus，确定II型糖尿病是否与 认知功能降低。 在与医疗保健隔离的人中 认知功能障碍可能导致无法遵循治疗计划， 保持自我保健，并适当确定何时寻求医疗保健， 所有这些都可能导致较差的结果。 具体目的是（1）开发和管理一种工具来评估 美国原住民的认知功能，（2） 确定II型糖尿病是否与降低的水平有关 认知功能。 参与者，45至74岁的社区居民长老 几年，将从一组中的一个保留中确定 南达科他州印度卫生服务局的阿伯丁地区。 他们会的 接受采访以获得心理界功能的衡量；信息 关于人口和社会经济变量，其他风险因素 认知改变和糖尿病病史（在糖尿病组中）；和 葡萄糖控制的血液学测量。 病历审查将是 进行验证这些数据并获得有关此数据的其他信息 慢性疾病和疾病的历史以及最近的生理学 参数。 两组之间和内部的比较将使用 相关性，多元回归分析，多元分析 方差和协方差技术的分析。