The Investigation of Particulate Respiratory Matter to Inform Guidance for the Safe Distancing of Performers in a COVID-19 Pandemic (PERFORM-2)

对呼吸道颗粒物的调查，为在 COVID-19 大流行期间表演者的安全距离提供指导 (PERFORM-2)

基本信息

批准号：
EP/V050516/1
负责人：
Jonathan Reid
金额：
$ 55.5万
依托单位：
University of Bristol
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2021
资助国家：
英国
起止时间：
2021 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=EP%2FV050516%2F1
关键词：
Investigation Particulate Respiratory Matter Inform

项目摘要

Respiratory particles emitted during human exhalatory events by an individual infected with SARS-CoV-2 are known to span a wide size range, from large macroscopic droplets to small aerosol particles. Although these droplets (>5 micrometres diameter) and aerosols (<5 micrometres) are responsible for direct, indirect and airborne modes of viral transmission, the concentrations and fluxes expired during activities such as speaking, singing, playing musical instruments and exercising, are poorly quantified and, in some cases, remain completely unknown. An absence of data, essential to inform assessments of risk in restarting activities, has led to precautionary measures that severely restrict singing, musical performance and sport, across both the amateur and professional domains. Building on preliminary work with a cohort of professional musicians, we will provide a comprehensive analysis of aerosol and droplet emissions from singers covering a broad range of genres, as well as woodwind and brass instruments. Working in an orthopaedic operating theatre, an environment of "zero aerosol" background, we will extend our study to quantify respirable particles exhaled by amateur musicians and individuals undertaking exercise, explore rigorously the distance of large droplet transmission and aerosol flux, focusing on super-emitters, and work with speech and language therapists to understand the risks of aerosol generating procedures used during therapy. In a range of venue types (from a modern auditorium to an historic church), we will measure the dynamics of aerosol dispersion and clearance, informing computational fluid dynamics models of aerosol spread and assessments of exposure risk.

已知感染SARS-COV-2的个体在人类呼气事件期间发出的呼吸道颗粒跨越了较宽的范围，从大宏观液滴到小气溶胶颗粒。尽管这些液滴（> 5微米直径）和气溶胶（<5微米）负责直接，间接和空中病毒传播的模式，但在诸如演讲，演唱，演奏乐器和锻炼等活动期间的浓度和通量过期量化，在某些情况下仍然是完全未知的。缺乏数据，对于重新启动活动中的风险评估的必要条件至关重要，导致了预防措施，这些措施严重限制了业余和专业领域的唱歌，音乐表现和运动。我们将与一系列专业音乐家的初步工作建立，我们将对歌手的气溶胶和液滴排放进行全面分析，这些歌手涵盖了广泛的流派，以及木管乐器和铜管乐器。在骨科手术室，一个“零气雾剂”背景的环境中，我们将扩展研究，以量化由业余音乐家和个人进行锻炼所呼出的可吸入的颗粒，严格探索大型水滴传播和气溶胶磁通量的距离，重点是超级 - 超级 - 发射器，并与言语和语言治疗师一起了解治疗过程中使用的气溶胶生成程序的风险。在各种场地类型（从现代礼堂到历史教堂）中，我们将衡量气溶胶分散和清除的动力学，为气溶胶传播的计算流体动力学模型提供信息，并评估暴露风险。

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Aerosol and droplet generation from performing with woodwind and brass instruments

DOI：
10.1080/02786826.2021.1947470
发表时间：
2021-06-29
期刊：
AEROSOL SCIENCE AND TECHNOLOGY
影响因子：
5.2
作者：
McCarthy, Lauren P.;Orton, Christopher M.;Bzdek, Bryan R.
通讯作者：
Bzdek, Bryan R.

Comparing aerosol number and mass exhalation rates from children and adults during breathing, speaking and singing.

DOI：
10.1098/rsfs.2021.0078
发表时间：
2022-04-06
期刊：
Interface focus
影响因子：
4.4
作者：
Archer J;McCarthy LP;Symons HE;Watson NA;Orton CM;Browne WJ;Harrison J;Moseley B;Philip KEJ;Calder JD;Shah PL;Bzdek BR;Costello D;Reid JP
通讯作者：
Reid JP

A comparison of respiratory particle emission rates at rest and while speaking or exercising.

DOI：
10.1038/s43856-022-00103-w
发表时间：
2022
期刊：
COMMUNICATIONS MEDICINE
影响因子：
0
作者：
Orton, Christopher M.;Symons, Henry E.;Moseley, Benjamin;Archer, Justice;Watson, Natalie A.;Philip, Keir E. J.;Sheikh, Sadiyah;Saccente-Kennedy, Brian;Costello, Declan;Browne, William J.;Calder, James D.;Bzdek, Bryan R.;Hull, James H.;Reid, Jonathan P.;Shah, Pallav L.
通讯作者：
Shah, Pallav L.

Spatiotemporal droplet dispersion measurements demonstrate face masks reduce risks from singing: results from the COvid aNd FacEmaSkS Study (CONFESS)

时空液滴分散测量表明口罩可降低唱歌风险：COvid 和 FacEmaSkS 研究 (CONFESS) 的结果